scholarly journals Osteoporosis: An Age-Related and Gender-Specific Disease – A Mini-Review

Gerontology ◽  
2008 ◽  
Vol 55 (1) ◽  
pp. 3-12 ◽  
Author(s):  
Peter Pietschmann ◽  
Martina Rauner ◽  
Wolfgang Sipos ◽  
Katharina Kerschan-Schindl
Keyword(s):  
Specific Disease ◽  
Age Related ◽  
And Gender ◽  
Gender Specific

Computer-Aided Joint Space Analysis (CAJSA) of the Proximal-Interphalangeal Joint—Normative Age-Related and Gender Specific Data

2007 ◽  
Vol 14 (5) ◽  
pp. 594-602 ◽  
Author(s):  
Alexander Pfeil ◽  
Joachim Böttcher ◽  
Bettina E. Seidl ◽  
Max L. Schäfer ◽  
Andreas Hansch ◽  
...  
Keyword(s):  
Joint Space ◽  
Proximal Interphalangeal Joint ◽  
Interphalangeal Joint ◽  
Specific Data ◽  
Space Analysis ◽  
Age Related ◽  
Computer Aided ◽  
And Gender ◽  
Gender Specific

Distinct phenotypic features and gender-specific disease manifestations in a Spanish family with desmin L370P mutation

2006 ◽  
Vol 16 (8) ◽  
pp. 498-503 ◽  
Author(s):  
Manuel Arias ◽  
Julio Pardo ◽  
Patricia Blanco-Arias ◽  
María-Jesús Sobrido ◽  
Susana Arias ◽  
...  
Keyword(s):  
Specific Disease ◽  
Spanish Family ◽  
Phenotypic Features ◽  
And Gender ◽  
Gender Specific

Abstract 708: Age and Gender Specific Changes in Tissue Doppler Derived Diastolic Index: A Doppler Echocardiographic Study in Healthy Individuals and Hypertensive Patients

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Hiroyuki Okura ◽  
Yuko Takada ◽  
Azusa Yamabe ◽  
Iku Toda ◽  
Minoru Yoshiyama ◽  
...  
Keyword(s):  
Diastolic Function ◽  
Diastolic Heart Failure ◽  
Female Gender ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Age And Gender ◽  
Male And Female ◽  
Age Related ◽  
And Gender ◽  
Gender Specific

Although left ventricular diastolic function has been shown to deteriorate with advancing age, its gender specific change is unknown. The aim of this study was to investigate age and gender specific changes in tissue Doppler derived left ventrisular diastolic index. A total of 1,333 healthy individual without known heart disease (mean age 55 years, range 10–89) and 138 patients with hypertension (mean 65 years, range 50–89) were enrolled and studied. Using Doppler echocardiography, peak early mitral annular velocity (E′) was recorded and measured from apical 4 chamber view. E′ value was compared between male and female in each age group. (Figure ) Among those aged between 10–19, E′ was similar between male and female. E′ progressively decline with advancing age in both gender, but more so in male than in female until age 50. In subjects with age 50–59 years (mean 55 years), E′ become identical in male and female. After 50 years, E′ decline more so in female than in male. Similarly, E′ was significantly lower in elderly women among hypertensive population. Age-related changes in diastolic indices were gender specific. In the elderly population diastolic function deteliorate more significantly in female gender than in male. These results may explaine the relatively higher incidence in elderly female among patients with diastolic heart failure and higher cardiovascular mortality in female gender.

scholarly journals Physiological matrix metalloproteinase concentrations in serum during childhood and adolescence, using Luminex® Multiplex technology

2005 ◽  
Vol 43 (12) ◽  
Author(s):  
Kathryn M. Thrailkill ◽  
Cindy S. Moreau ◽  
Gael Cockrell ◽  
Pippa Simpson ◽  
Rajiv Goel ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinase ◽  
Tissue Growth ◽  
Childhood And Adolescence ◽  
Serum Samples ◽  
Age Related ◽  
Gender Specific Differences ◽  
And Gender ◽  
Remodeling Of Extracellular Matrix ◽  
Gender Specific

AbstractMatrix metalloproteinases are a family of zinc-dependent proteinases which are involved in the breakdown and remodeling of extracellular matrix. As children grow and adolescents reach pubescence, their bodies undergo changes that require age-related morphogenesis of the extracellular matrix, possibly requiring unique patterns of matrix metalloproteinase (MMP) expression during periods of rapid tissue growth (i.e., childhood) or accelerated tissue remodeling and expansion (i.e., adolescence). Therefore, we have characterized age-specific and gender-specific differences in circulating concentrations of MMPs (specifically MMP-1, -2, -3, -8 and -9) in 189 serum samples obtained from healthy subjects, aged 2–18 years. MMP concentrations were measured using Fluorokine

Computer-aided joint space analysis of the metacarpal-phalangeal and proximal-interphalangeal finger joint: normative age-related and gender-specific data

2007 ◽  
Vol 36 (9) ◽  
pp. 853-864 ◽  
Author(s):  
Alexander Pfeil ◽  
Joachim Böttcher ◽  
Bettina E. Seidl ◽  
Jens-Peter Heyne ◽  
Alexander Petrovitch ◽  
...  
Keyword(s):  
Joint Space ◽  
Finger Joint ◽  
Specific Data ◽  
Space Analysis ◽  
Age Related ◽  
Computer Aided ◽  
And Gender ◽  
Gender Specific

scholarly journals The Bone-Muscle Relationship in Men and Women

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Thomas F. Lang
Keyword(s):  
Bone Structure ◽  
Molecular Signaling ◽  
Muscle Forces ◽  
Age Related ◽  
Muscle Tissues ◽  
Large Growth ◽  
And Gender ◽  
Gender Specific ◽  
Reduce Bone Loss ◽  
Bone Dimensions

Muscle forces are a strong determinant of bone structure, particularly during the process of growth and development. The gender divergence in the bone-muscle relationship becomes strongly evident during adolescence. In females, growth is characterized by increased estrogen levels and increased mass and strength of bone relative to that of muscle, whereas in men, increases in testosterone fuel large increases in muscle, resulting in muscle forces that coincide with a large growth in bone dimensions and strength. In adulthood, significant age-related losses are observed for both bone and muscle tissues. Large decrease in estrogen levels in women appears to diminish the skeleton's responsiveness to exercise more than in men. In contrast, the aging of the muscle-bone axis in men is a function of age related declines in both hormones. In addition to the well-known age related changes in the mechanical loading of bone by muscle, newer studies appear to provide evidence of age- and gender-related variations in molecular signaling between bone and muscle that are independent of purely mechanical interactions. In summary, gender differences in the acquisition and age-related loss in bone and muscle tissues may be important for developing gender-specific strategies for using exercise to reduce bone loss with aging.

Age-specific and gender-specific radiation risks in paediatric angiography and interventional cardiology: conversion coefficients and risk reference values

2020 ◽  
Vol 93 (1110) ◽  
pp. 20190869
Author(s):  
Angeliki Karambatsakidou ◽  
Kristoffer Steiner ◽  
Annette Fransson ◽  
Gavin Poludniowski
Keyword(s):  
Cancer Risk ◽  
Reference Values ◽  
Radiation Risk ◽  
Age Groups ◽  
Cancer Death ◽  
Age Related ◽  
Conversion Coefficients ◽  
And Gender ◽  
Cardiac Catheterizations ◽  
Gender Specific

Objectives: To estimate risk for exposure-induced cancer death (REID), organ-specific risks of exposure-induced cancer death (REIDHT) and associated conversion coefficients (CCREID:KAP=REID/kerma-area product (KAP), CCREIDHT:KAP=REIDHT/KAP) in paediatric cardiac catheterizations using data from radiation dose structured reports (RDSR). A novel risk surveillance tool consisting of age-specific and gender-specific risk reference values (RRVs) related to population cancer risk is suggested. Methods: The PCXMC v.2.0 code is used together with exposure-related information from RDSR from a cohort of 238 children to assess cancer risks and related conversion coefficients. The KAP corresponding to 1 in 1000 of increased REID is used to define age-specific and gender-specific KAP values to monitor risk in such patient cohorts, here denoted as RRVs. Results: The REID estimates ranged from below 1 up to 300 in 100,000, and the RRVs for the different age groups and gender ranged from 0.77 Gycm2 and 2.1 Gycm2 for neonates (female, male) to 11 Gycm2 and 25 Gycm2 for 15-year-olds (female, male). The CCREID:KAP and CCREIDHT:KAP decreased biexponentially with increased age, being notably higher for female patients. Conclusions: Prominent risk contributing organs were the lungs and the (female) breast. The concept of age-specific and gender-specific RRVs related to population cancer risk is introduced and is intended to be used as a supporting tool for physicians performing such interventions. Advances in knowledge: Age-related and gender-related conversion coefficients for radiation risk, CCREID:KAP and CCREIDHT:KAP, are introduced and a novel risk surveillance concept, the RRV, is suggested for paediatric cardiac catheterizations.

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