Simultaneous Determination of the Capacity of the Vascular Bed and Capillary Blood Flow in the Normal Myocardium of the Rat and in Two Types of Experimental Necrosis

Cardiology ◽  
1968 ◽  
Vol 52 (3) ◽  
pp. 138-144
Author(s):  
K. Raicušan ◽  
V. Aschenbrenner ◽  
J. Měšcan ◽  
Z. Turek
1961 ◽  
Vol 9 (4) ◽  
pp. 945-962 ◽  
Author(s):  
MARIO RIGATTO ◽  
GERARD M. RIGATTO ◽  
ALFRED P. FISHMAN

2020 ◽  
Vol 19 (4) ◽  
pp. 87-91
Author(s):  
A. A. Fedorovich ◽  
A. Yu. Gorshkov ◽  
O. M. Drapkina

A brief review is dedicated to the latest advances in the field of non-invasive studies of capillary blood flow in humans based on the developments of Russian scientists. Modern computer technologies have significantly expanded the capabilities of researchers and make it possible to obtain information about fundamental processes at the level of the metabolic link of the vascular bed not only in a hospital setting, but also in a remote access mode, which is extremely important in the context of a pandemic caused by the SARS-CoV-2 virus.


Pharmacology ◽  
1967 ◽  
Vol 17 (2) ◽  
pp. 119-128
Author(s):  
K. Rakusan ◽  
W. Du Mesnil De Rochemont ◽  
J. Hanlon ◽  
W. Braasch ◽  
H. Tschopp ◽  
...  

1962 ◽  
Vol 17 (1) ◽  
pp. 135-141 ◽  
Author(s):  
Håkan Linderholm ◽  
Philip Kimbel ◽  
David H. Lewis ◽  
Arthur B. Dubois

Methods for the measurement of mean and instantaneous pulmonary capillary blood flow by means of a horizontal body plethysmograph have been described. Methods of calibration were described for the determination of the rate with which N2O was taken up by the blood from the recorded plethysmographic pressure. They included a correction factor for leaks, and for changes from mainly adiabatic to more isothermal conditions. Duplicate determinations with the plethysmographic N2O uptake method of mean pulmonary capillary blood flow showed a good reproducibility and comparison with the direct Fick method during cardiac catheterization on six patients did not show any statistically significant difference. Examples illustrating the use of the method for comparison between the pulmonary vascular pressure gradient and the pulmonary capillary pulse flow curves are presented. Submitted on June 26, 1961


2019 ◽  
Vol 89 (1-2) ◽  
pp. 5-12
Author(s):  
Alon Harris ◽  
Brent Siesky ◽  
Amelia Huang ◽  
Thai Do ◽  
Sunu Mathew ◽  
...  

Abstract. Introduction: To investigate the effects of a lutein complex supplementation on ocular blood flow in healthy subjects. Materials and Methods: Sixteen healthy female patients (mean age 36.8 ± 12.1 years) were enrolled in this randomized, placebo-controlled, double-blinded, two-period crossover study. Subjects received daily an oral dose of the lutein with synergistic phytochemicals complex (lutein (10 mg), ascorbic acid (500 mg), tocopherols (364 mg), carnosic acid (2.5 mg), zeaxanthin (2 mg), copper (2 mg), with synergistic effects in reducing pro-inflammatory mediators and cytokines when administered together in combination) and placebo during administration periods. Measurements were taken before and after three-week supplementation periods, with crossover visits separated by a three-week washout period. Data analysis included blood pressure, heart rate, intraocular pressure, visual acuity, contrast sensitivity detection, ocular perfusion pressure, confocal scanning laser Doppler imaging of retinal capillary blood flow, and Doppler imaging of the retrobulbar blood vessels. Results: Lutein complex supplementation produced a statistically significant increase in mean superior retinal capillary blood flow, measured in arbitrary units (60, p = 0.0466) and a decrease in the percentage of avascular area in the superior (−0.029, p = 0.0491) and inferior (−0.023, p = 0.0477) retina, as well as reduced systolic (−4.06, p = 0.0295) and diastolic (−3.69, p = 0.0441) blood pressure measured in mmHg from baseline. Data comparison between the two supplement groups revealed a significant decrease in systemic diastolic blood pressure (change from pre- to post-treatment with lutein supplement (mean (SE)): −3.69 (1.68); change from pre- to post-treatment with placebo: 0.31 (2.57); p = 0.0357) and a significant increase in the peak systolic velocity (measured in cm/sec) in the central retinal artery (change from pre- to post-treatment with lutein supplement: 0.36 (0.19); change from pre- to post-treatment with placebo: −0.33 (0.21); p = 0.0384) with lutein complex supplement; data analyses from the placebo group were all non-significant. Discussion: In healthy participants, oral administration of a lutein phytochemicals complex for three weeks produced increased ocular blood flow biomarkers within retinal vascular beds and reduced diastolic blood pressure compared to placebo.


Sign in / Sign up

Export Citation Format

Share Document