scholarly journals Thirteen-Year Disease-Free Survival after Surgery for Cystic Duct Carcinoma: A Case Report

2008 ◽  
Vol 2 (3) ◽  
pp. 428-432 ◽  
Author(s):  
Zine Abedine Benchellal ◽  
Kountélé Gona Soro ◽  
Isabelle Orain ◽  
Hélène Poret ◽  
Abd Hak Ferhi ◽  
...  
2018 ◽  
Vol 158 (6) ◽  
pp. 1035-1041 ◽  
Author(s):  
Phillip Huyett ◽  
Umamaheswar Duvvuri ◽  
Robert L. Ferris ◽  
Jonas T. Johnson ◽  
Barry M. Schaitkin ◽  
...  

Objectives To investigate the clinical predictors and survival implications of perineural invasion (PNI) in parotid gland malignancies. Study Design Case series with chart review. Setting Tertiary care medical center. Subjects and Methods Patients with parotid gland malignancies treated surgically from 2000 to 2015 were retrospectively identified in the Head and Neck Cancer Registry at a single institution. Data points were extracted from the medical record and original pathology reports. Results In total, 186 patients with parotid gland malignancies were identified with a mean follow-up of 5.2 years. Salivary duct carcinoma (45), mucoepidermoid carcinoma (44), and acinic cell carcinoma (26) were the most common histologic types. A total of 46.2% of tumors were found to have PNI. At the time of presentation, facial nerve paresis (odds ratio [OR], 64.7; P < .001) and facial pain (OR, 3.7; P = .002) but not facial paresthesia or anesthesia (OR, 2.8, P = .085) were predictive of PNI. Malignancies with PNI were significantly more likely to be of advanced T and N classification, be high-risk pathologic types, and have positive margins and angiolymphatic invasion. PNI positivity was associated with worse overall (hazard ratio, 2.62; P = .001) and disease-free survival (4.18; P < .001) on univariate Cox regression analysis. However, when controlling for other negative prognosticators, age, and adjuvant therapy, PNI did not have a statistically significant effect on disease-free or overall survival. Conclusions PNI is strongly correlated with more aggressive parotid gland malignancies but is not an independent predictor of worse survival. Facial paresis and pain were predictive of PNI positivity, and facial paresis correlated with worse overall and disease-free survival.


2011 ◽  
Vol 99 ◽  
pp. S368
Author(s):  
A. Parisi ◽  
S. Takanen ◽  
V. Graziano ◽  
B. Resuli ◽  
S. Fouraki ◽  
...  

2014 ◽  
Vol 158 (3) ◽  
pp. 474-478 ◽  
Author(s):  
Martin Straka ◽  
Renata Soumarova ◽  
Jan Bulejcik ◽  
Martin Banik ◽  
Mikulas Pura ◽  
...  

2020 ◽  
Vol 6 (2) ◽  
pp. 29
Author(s):  
Madison N Crank ◽  
Arslan Iqbal ◽  
Michael Abdelmasseh ◽  
Mohamed Alsharedi ◽  
Doreen Griswold ◽  
...  

2014 ◽  
Vol 20 (Supplement) ◽  
pp. 470-473
Author(s):  
Alberto Testori ◽  
Stefano Meroni ◽  
Umberto Cariboni ◽  
Valentina Errico ◽  
Emanuele Voulaz ◽  
...  

2018 ◽  
Vol 12 (1) ◽  
Author(s):  
Francesco D’Amico ◽  
Alessandra Bertacco ◽  
Maurizio Cesari ◽  
Claudia Mescoli ◽  
Giorgio Caturegli ◽  
...  

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