Spatial and Temporal Resolution of Serotonin-Induced Changes in Intracellular Calcium in a Cultured Arterial Smooth Muscle Cell Line

1991 ◽  
Vol 28 (1-3) ◽  
pp. 252-261
Author(s):  
William F. Goldman
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Intracellular Calcium ◽  
Cell Line ◽  
Muscle Cell ◽  
Temporal Resolution ◽  
Arterial Smooth Muscle Cell ◽  
Arterial Smooth Muscle ◽  
Induced Changes ◽  
Muscle Cell Line

1429: Upregulation of Rho-Kinase in a Human Corpus Cavernosum Smooth Muscle Cell Line in Response to Hypoxia

2004 ◽  
Vol 171 (4S) ◽  
pp. 376-377
Author(s):  
Yongmu Zheng ◽  
Shaohua Chang ◽  
Alan J. Wein ◽  
Samuel Chacko ◽  
Michael E. DiSanto
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Cell Line ◽  
Muscle Cell ◽  
Corpus Cavernosum ◽  
Rho Kinase ◽  
Muscle Cell Line

Phenotypic Heterogeneity of Rat Arterial Smooth Muscle Cell Clones

1996 ◽  
Vol 16 (6) ◽  
pp. 815-820 ◽  
Author(s):  
Marie-Luce Bochaton-Piallat ◽  
Patricia Ropraz ◽  
Françoise Gabbiani ◽  
Giulio Gabbiani
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Phenotypic Heterogeneity ◽  
Arterial Smooth Muscle Cell ◽  
Arterial Smooth Muscle ◽  
Cell Clones

An In Vitro Study of Nano-fiber Polymers for Guided Vascular Regeneration

2001 ◽  
Vol 711 ◽  
Author(s):  
Derick C. Miller ◽  
Anil Thapa ◽  
Karen M. Haberstroh ◽  
Thomas J. Webster
Keyword(s):  
Smooth Muscle ◽  
Cell Adhesion ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Surrounding Tissue ◽  
Arterial Smooth Muscle Cell ◽  
Arterial Smooth Muscle ◽  
Cell Functions ◽  
Fiber Dimensions

ABSTRACTBiomaterials that successfully integrate into surrounding tissue should match not only the tissue's mechanical properties, but also the dimensions of the associated nano-structured extra-cellular matrix (ECM) components. The goal of this research was to use these ideals to develop a synthetic, nano-structured, polymeric biomaterial that has cytocompatible and mechanical behaviors similar to that of natural vascular tissue. In a novel manner, poly-lactic acid/polyglycolic acid (PLGA) (50/50 wt.% mix) and polyurethane were separately synthesized to possess a range of fiber dimensions in the micron and nanometer regime. Preliminary results indicated that decreasing fiber diameter on both PLGA and PU enhanced arterial smooth muscle cell adhesion; specifically, arterial smooth muscle cell adhesion increased 23% when PLGA fiber dimensions decreased from 500 to 50 nm and increased 76% on nano-structured, compared to conventional structured, polyurethane. However, nano-structured PLGA decreased endothelial cell adhesion by 52%, whereas adhesion of these same cells was increased by 50% on polyurethane. For these reasons, the present in vitro study provides the first evidence that polymer fiber dimensions can be used to selectively control cell functions for vascular prosthesis.

Sign in / Sign up

Export Citation Format

Share Document