Femoral segments from the metathoracic leg of the freshly molted cockroach nymph, Leucophaea maderae, were removed and were prepared for electron microscopy. The femoral cuticle with underlying epidermal cells encloses muscle, nerves, tracheae, tracheoles, and the hemocoel. In the insect open circulatory system the hemocoel contains hemolymph and hemocytes. Some of the known functions of insect hemocytes are phagocytosis, encapsulation, melanization, Wound healing, coagulation and possible transformation into other tissues. Previous studies of the agranular and granular hemocytes however lack the fine structure that is helpful in determining cellular function.The several different types of granular hemocytes have a general elliptical appearance, large nucleus, and prominent cytoplasmic granules. The most abundant type of granules are the membrane-bounded, roughly spherical, opaque inclusions which average about 1 to 2μ in diameter. These dense inclusions resemble vertebrate melanosomes. Other granules with an organized substructure are reminiscent of the vertebrate premelanosomes (Figs. 1, 2). In certain planes of section the premelanosome-like granules reveal that the internal configurations are microtubules which measure about 250A in diameter.