Comparative Study of Cluster and Conventional Immunotherapy Schedules with Dermatophagoides pteronyssinus in the Treatment of Persistent Allergic Rhinitis

2009 ◽  
Vol 148 (2) ◽  
pp. 161-169 ◽  
Author(s):  
Luo Zhang ◽  
Chengshuo Wang ◽  
Demin Han ◽  
Xiangdong Wang ◽  
Yan Zhao ◽  
...  
2018 ◽  
Vol 23 (2) ◽  
pp. 206
Author(s):  
Erhan ZEYTUN ◽  
Salih DOĞAN ◽  
Edhem Ünver ◽  
Fatih ÖZÇÜÇEK

This study was conducted to determine the sensitivity to Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes with skin prick tests (SPT) and serologic tests in patients with allergic rhinitis (AR), and to specifically search for those mites in homes of patients. A total of 51 participants, (23 patients and 28 controls) were utilized. Skin-prick tests with D. pteronyssinus and D. farinae allergens were performed on all participants, and serum levels of allergen-specific lgE and total IgE were also measured. Dust samples were collected from homes of all participants and examined under a stereo microscope. 977 D. pteronyssinus (mean 44.4/g) and 24 D. farinae (mean 4.0/g) were isolated from the homes of patients, whereas 35 D. pteronyssinus (mean 4.4/g), and four D. farinae (mean 2.0/g) were isolated from the homes of the controls. Patients with D. pteronyssinus in their homes had 95.5% sensitivity to the species according to SPT and 27.3 according to IgE. Patients with D. farinae in their homes had 83.3% sensitivity to the species according to SPT, and 50% according to IgE. Dermatophagoides pteronyssinus sensitivity in the controls was detected as 12.5% according to SPT; however, D. farinae sensitivity was not detected according to both SPT and mite-specific IgE. Differences between patients and controls utilizing SPT results was statistically significant, but not when using mite-specific IgE results. As a result, it was determined that patients with AR in Erzincan province were sensitized to D. pteronyssinus and D. farinae, and that their homes contained those species. It may be helpful to consider these findings in clinical assessment of patients with AR, and also in treatment utilizing immunotherapy techniques.


2020 ◽  
Vol 34 ◽  
pp. 205873842090718
Author(s):  
Natalia Ukleja-Sokołowska ◽  
Ewa Gawrońska-Ukleja ◽  
Kinga Lis ◽  
Magdalena Żbikowska-Gotz ◽  
Rafał Adamczak ◽  
...  

Shrimp tropomyosin has a similar structure to house dust mite (HDM) tropomyosin. In this research, 232 adult patients with symptoms of persistent allergic rhinitis were randomly selected. In the group, 59% were sensitized to Dermatophagoides pteronyssinus and 57.8% to Dermatophagoides farinae. In total, 128 (55.2%) patients were sensitized to both HDM species and 143 (61.6%) to at least one. Slightly over a quarter (25.4%) of patients were sensitized to shrimp. Of the 35 shrimp-sensitized patients, the sensitization to Der p 10 and Pen a 1 was found in 11 cases (31.4%). There was a strong correlation between IgE Pen a 1 and IgE Der p 10 concentrations. The results indicate that there are other allergens responsible for a high incidence of shrimp sensitization in HDM-sensitized patients. A high convergence of Der p 10 and Pen a 1 levels may indicate that the determination of just one of the above is reasonable.


2018 ◽  
Vol 141 (2) ◽  
pp. AB129 ◽  
Author(s):  
Fernando Pineda ◽  
Ruperto Gonzalez-Perez ◽  
Paloma Poza-Guedes ◽  
Miriam Castillo ◽  
Inmaculada Sanchez-Machin ◽  
...  

2018 ◽  
Vol 23 (2) ◽  
pp. 404
Author(s):  
ERHAN ZEYTUN ◽  
SALİH DOĞAN ◽  
EDHEM ÜNVER ◽  
FATİH ÖZÇİÇEK

The authors are sorry that they made a mistake in spelling the family name of the first author on line 4 of page 206 in Zeytun et al. (2018): EYTUN should be ZEYTUN.


Author(s):  
E Ocak ◽  
S Mulazimoglu ◽  
D Kocaoz ◽  
E Mirici ◽  
E Dagli ◽  
...  

Abstract Objective To investigate the effects of nasal irrigation with sodium hyaluronate and surfactant solutions on mucociliary clearance time in patients with mild persistent allergic rhinitis. Methods A total of 120 patients diagnosed with mild persistent allergic rhinitis were enrolled in this prospective study. The patients were allocated randomly to the surfactant, sodium hyaluronate or isotonic saline (as a control) nasal irrigation group. The mucociliary clearance times and improvements in mucociliary clearance times were compared. Results Improvements in mean mucociliary clearance time were significantly greater in the surfactant and sodium hyaluronate groups than in the control group (p < 0.01). The mean post-treatment mucociliary clearance time of the surfactant group was significantly lower than that of the control (p < 0.001) and sodium hyaluronate groups (p = 0.03). Conclusion Surfactant and sodium hyaluronate nasal irrigation solutions may both be used as adjunctive treatments for allergic rhinitis. Surfactant nasal irrigation resulted in better mucociliary clearance times.


2020 ◽  
Vol 129 (6) ◽  
pp. 542-547
Author(s):  
Su Il Kim ◽  
Oh Eun Kwon ◽  
Jung Min Park ◽  
Jeon Gang Doo ◽  
Seok Hyun Kim ◽  
...  

Objectives: This study investigated whether the biomarkers present in nasal fluid reflect the severity of symptoms in patients with persistent allergic rhinitis (PAR). Methods: We enrolled 29 PAR patients complaining of nasal symptoms and testing positive to skin prick test. Patients’ total nasal symptom score (TNSS) was measured and their nasal lavage fluid (NALF) was collected. The levels of biomarkers including Clara cell protein 16 (CC16), tryptase, and interleukin 5 (IL-5) in NALF were determined via enzyme-linked immunosorbent assay (ELISA). Results: PAR patients were classified into persistent mild and persistent moderate-to-severe groups according to the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines. The CC16 alone was significantly negatively correlated with TNSS ( P < .05). Further, the CC16 level was significantly lower in persistent moderate-to-severe group than persistent mild group of patients ( P < .05). Conclusions: The levels of CC16 alone among several NALF biomarkers showed an inverse correlation with symptoms of PAR patients.


PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0133162 ◽  
Author(s):  
Hui-Qin Tian ◽  
Xin-Yuan Chen ◽  
Ying Lu ◽  
Wen-Min Lu ◽  
Mei-Lin Wang ◽  
...  

2011 ◽  
Vol 155 (1) ◽  
pp. 57-62 ◽  
Author(s):  
J. Meng ◽  
J. Xuan ◽  
X. Qiao ◽  
X. Li ◽  
S. Liu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document