The 1918 Influenza Pandemic: Lessons from the Past Raise Questions for the Future

2008 ◽  
pp. 272-286 ◽  
Author(s):  
John Steel ◽  
Peter Palese
2021 ◽  
Vol 111 (3) ◽  
pp. 430-437
Author(s):  
Siddharth Chandra ◽  
Julia Christensen ◽  
Madhur Chandra ◽  
Nigel Paneth

The global influenza pandemic that emerged in 1918 has become the event of reference for a broad spectrum of policymakers seeking to learn from the past. This article sheds light on multiple waves of excess mortality that occurred in the US state of Michigan at the time with insights into how epidemics might evolve and propagate across space and time. We analyzed original monthly data on all-cause deaths by county for the 83 counties of Michigan and interpreted the results in the context of what is known about the pandemic. Counties in Michigan experienced up to four waves of excess mortality over a span of two years, including a severe one in early 1920. Some counties experienced two waves in late 1918 while others had only one. The 1920 wave propagated across the state in a different manner than the fall and winter 1918 waves. The twin waves in late 1918 were likely related to the timing of the statewide imposition of a three-week social distancing order. Michigan’s experience holds sobering lessons for those who wish to understand how immunologically naïve populations encounter novel viral pathogens.


2010 ◽  
Vol 38 ◽  
pp. e10-e20 ◽  
Author(s):  
David M. Morens ◽  
Jeffery K. Taubenberger ◽  
Hillery A. Harvey ◽  
Matthew J. Memoli

Author(s):  
Sharon DeWitte ◽  
Amanda Wissler

The ongoing COVID-19 pandemic has justifiably captured the attention of people around the world since late 2019. It has produced in many people a new perspective on or, indeed, a new realization about our potential vulnerability to emerging infectious diseases. However, our species has experienced numerous catastrophic disease pandemics in the past, and in addition to concerns about the harm being produced during the pandemic and the potential long-term sequelae of the disease, what has been frustrating for many public health experts, anthropologists, and historians is awareness that many of the outcomes of COVID-19 are not inevitable and might have been preventable had we actually heeded lessons from the past. We are currently witnessing variation in exposure risk, symptoms, and mortality from COVID-19, but these patterns are not surprising given what we know about past pandemics. We review here the literature on the demographic and evolutionary consequences of the Second Pandemic of Plague (ca. fourteenth–nineteenth centuries C.E.) and the 1918 influenza pandemic, two of the most devastating pandemics in recorded human history. These both provide case studies of the ways in which sociocultural and environmental contexts shape the experiences and outcomes of pandemic disease. Many of the factors at work during these past pandemics continue to be reproduced in modern contexts, and ultimately our hope is that by highlighting the outcomes that are at least theoretically preventable, we can leverage our knowledge about past experiences to prepare for and respond to disease today.


2021 ◽  
Author(s):  
Kaspar Staub

In many places the current coronavirus pandemic is the most severe pandemic since the 1918 influenza pandemic (“Spanish flu”). In many European countries before 2020, past experiences with pandemics had not been sufficiently studied and were no longer present in the minds of the general public or authorities. This article highlights scenarios from the past that may offer guidance as we move towards autumn and winter 2021. High quality morbidity data from the Swiss canton of Bern 1918-1930 is re-used here and complemented with similar data from 1957, SARS-CoV-2 data from 2020, as well as temperature series for all three years. A first possible scenario that emerges from experiences in all three pandemic years is that the onset of the fall waves at the beginning of October, occurred 0-2 weeks after the first drop in temperatures at the end of September (calendar week 39). This temporal coincidence can also be coincidental, and does not imply causality. However, this risk is also present for the coming autumn of 2021, all the more so if the case numbers will not be low everywhere then because of the delta variant. When temperatures start to fall, people will stay indoors more, which will increase the risk of infection for the unprotected or only partially protected subgroups of the population. In the winter of 1920, the influenza virus returned in the form of a relatively strong “echo” wave probably due to incomplete immunization of the population and/or virus mutations, and thereafter in the form of milder seasonal waves. This is a second scenario that many experts also consider possible for SARS-CoV-2. We do not know yet what will happen in autumn/winter 2021 and in the years to come. However, the past at least provides some scenarios of what happened in partly comparable situations in 1918 and thereafter. To not at least consider these possible scenarios in pandemic planning for the coming period would be a missed opportunity.


Open Health ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 40-49
Author(s):  
Madiha Asghar ◽  
Misbahud Din ◽  
Abdul Waris ◽  
Muhammad Talha Yaseen ◽  
Tanzeel Zohra ◽  
...  

Abstract The coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was first reported in December, 2019, in Wuhan, China. Even the public health sector experts could not anticipate that the virus would spread rapidly to create the worst worldwide crisis in more than a century. The World Health Organization (WHO) declared COVID-19 a public health emergency on January 30, 2020, but it was not until March 11, 2020 that the WHO declared it a global pandemic. The epidemiology of SARS-CoV-2 is different from the SARS coronavirus outbreak in 2002 and the Middle East Respiratory Syndrome (MERS) in 2012; therefore, neither SARS nor MERS could be used as a suitable model for foreseeing the future of the current pandemic. The influenza pandemic of 1918 could be referred to in order to understand and control the COVID-19 pandemic. Although influenza and the SARS-CoV-2 are from different families of viruses, they are similar in that both silently attacked the world and the societal and political responses to both pandemics have been very much alike. Previously, the 1918 influenza pandemic and unpredictability of the second wave caused distress among people as the first wave of that outbreak (so-called Spanish flu) proved to be relatively mild compared to a much worse second wave, followed by smaller waves. As of April, 2021, the second wave of COVID-19 has occurred around the globe, and future waves may also be expected, if the total population of the world is not vaccinated. This article aims to highlight the key similarities and differences in both pandemics. Similarly, lessons from the previous pan-demics and various possibilities for the future course of COVID-19 are also highlighted.


mBio ◽  
2012 ◽  
Vol 3 (5) ◽  
Author(s):  
Jeffery K. Taubenberger ◽  
David Baltimore ◽  
Peter C. Doherty ◽  
Howard Markel ◽  
David M. Morens ◽  
...  

ABSTRACTThe influenza pandemic of 1918–1919 killed approximately 50 million people. The unusually severe morbidity and mortality associated with the pandemic spurred physicians and scientists to isolate the etiologic agent, but the virus was not isolated in 1918. In 1996, it became possible to recover and sequence highly degraded fragments of influenza viral RNA retained in preserved tissues from several 1918 victims. These viral RNA sequences eventually permitted reconstruction of the complete 1918 virus, which has yielded, almost a century after the deaths of its victims, novel insights into influenza virus biology and pathogenesis and has provided important information about how to prevent and control future pandemics.


CHANCE ◽  
2008 ◽  
Vol 21 (2) ◽  
pp. 55-60
Author(s):  
Mark Glickman ◽  
Gerardo Chowell ◽  
N. W. Hengartner ◽  
Catherine Ammon ◽  
Mac Hyman

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