Value of Morning Home Blood Pressure as a Predictor of Decline in Renal Function in Patients with Chronic Kidney Disease

2008 ◽  
Vol 28 (6) ◽  
pp. 982-989 ◽  
Author(s):  
Tomonari Okada ◽  
Toshiyuki Nakao ◽  
Hiroshi Matsumoto ◽  
Yume Nagaoka
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Home Blood Pressure

Histomorphometry of Feline Chronic Kidney Disease and Correlation With Markers of Renal Dysfunction

2012 ◽  
Vol 50 (1) ◽  
pp. 147-155 ◽  
Author(s):  
S. Chakrabarti ◽  
H. M. Syme ◽  
C. A. Brown ◽  
J. Elliott
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Image Analysis ◽  
Renal Function ◽  
Kidney Disease ◽  
Renal Dysfunction ◽  
Interstitial Fibrosis ◽  
Glomerular Hypertrophy ◽  
Renal Lesions ◽  
Postmortem Examinations

Chronic kidney disease is common in geriatric cats, but most cases have nonspecific renal lesions, and few studies have correlated these lesions with clinicopathological markers of renal dysfunction. The aim of this study was to identify the lesions best correlated with renal function and likely mediators of disease progression in cats with chronic kidney disease. Cats were recruited through 2 first-opinion practices between 1992 and 2010. When postmortem examinations were authorized, renal tissues were preserved in formalin. Sections were evaluated by a pathologist masked to all clinicopathological data. They were scored semiquantitatively for the severity of glomerulosclerosis, interstitial inflammation, and fibrosis. Glomerular volume was measured using image analysis; the percentage of glomeruli that were obsolescent was recorded. Sections were assessed for hyperplastic arteriolosclerosis and tubular mineralization. Kidneys from 80 cats with plasma biochemical data from the last 2 months of life were included in the study. Multivariable linear regression ( P < .05) was used to assess the association of lesions with clinicopathological data obtained close to death. Interstitial fibrosis was the lesion best correlated with the severity of azotemia, hyperphosphatemia, and anemia. Proteinuria was associated with interstitial fibrosis and glomerular hypertrophy, whereas higher time-averaged systolic blood pressure was associated with glomerulosclerosis and hyperplastic arteriolosclerosis.

Abstract P258: What Clinic Blood Pressure Best Protects Renal Function in Children With Chronic Kidney Disease?

Hypertension ◽  
2018 ◽  
Vol 72 (Suppl_1) ◽  
Author(s):  
Joseph T Flynn ◽  
Megan Carroll ◽  
Derek Ng ◽  
Brad Warady ◽  
Susan Furth
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Clinic Blood Pressure

Acute changes in home blood pressure after the Great East Japan Earthquake among patients with chronic kidney disease in Fukushima City

2012 ◽  
Vol 17 (5) ◽  
pp. 718-724 ◽  
Author(s):  
Kimio Watanabe ◽  
Yoshihiro Tani ◽  
Kenichi Tanaka ◽  
Yoshimitsu Hayashi ◽  
Koichi Asahi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Home Blood Pressure ◽  
Great East Japan Earthquake ◽  
Acute Changes

scholarly journals Progression of anemia and its relationship with renal function, blood pressure, and erythropoietin in rats with chronic kidney disease

2015 ◽  
Vol 44 (3) ◽  
pp. 342-354 ◽  
Author(s):  
Jacqueline K. Phillips ◽  
Rochelle Boyd ◽  
Mark B. Krockenberger ◽  
Gaetan Burgio
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease

scholarly journals Effects of renal denervation with a standard irrigated cardiac ablation catheter on blood pressure and renal function in patients with chronic kidney disease and resistant hypertension

2013 ◽  
Vol 34 (28) ◽  
pp. 2114-2121 ◽  
Author(s):  
Márcio Galindo Kiuchi ◽  
George Luiz Marques Maia ◽  
Maria Angela Magalhães de Queiroz Carreira ◽  
Tetsuaki Kiuchi ◽  
Shaojie Chen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Renal Denervation ◽  
Ablation Catheter ◽  
Cardiac Ablation

Association of home blood pressure variability with progression of chronic kidney disease

2012 ◽  
Vol 17 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Tomonari Okada ◽  
Hiroshi Matsumoto ◽  
Yume Nagaoka ◽  
Toshiyuki Nakao
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Blood Pressure Variability ◽  
Home Blood Pressure

scholarly journals Contribution of the Renal Nerves to Hypertension in a Rabbit Model of Chronic Kidney Disease

Hypertension ◽  
2020 ◽  
Vol 76 (5) ◽  
pp. 1470-1479
Author(s):  
Yusuke Sata ◽  
Sandra L. Burke ◽  
Cindy Gueguen ◽  
Kyungjoon Lim ◽  
Anna M.D. Watson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Rabbit Model ◽  
Renal Nerves ◽  
Monocyte Chemoattractant Protein 1 ◽  
Stage Renal Disease ◽  
Normalized Units ◽  
Renal Sympathetic

Overactivity of the sympathetic nervous system and high blood pressure are implicated in the development and progression of chronic kidney disease (CKD) and independently predict cardiovascular events in end-stage renal disease. To assess the role of renal nerves, we determined whether renal denervation (RDN) altered the hypertension and sympathoexcitation associated with a rabbit model of CKD. The model involves glomerular layer lesioning and uninephrectomy, resulting in renal function reduced by one-third and diuresis. After 3-week CKD, blood pressure was 13±2 mm Hg higher than at baseline ( P <0.001), and compared with sham control rabbits, renal sympathetic nerve activity was 1.2±0.5 normalized units greater ( P =0.01). The depressor response to ganglion blockade was also +8.0±3 mm Hg greater, but total norepinephrine spillover was 8.7±3.7 ng/min lower (both P <0.05). RDN CKD rabbits only increased blood pressure by 8.0±1.5 mm Hg. Renal sympathetic activity, the response to ganglion blockade and diuresis were similar to sham denervated rabbits (non-CKD). CKD rabbits had intact renal sympathetic baroreflex gain and range, as well as normal sympathetic responses to airjet stress. However, hypoxia-induced sympathoexcitation was reduced by −9±0.4 normalized units. RDN did not alter the sympathetic response to hypoxia or airjet stress. CKD increased oxidative stress markers Nox5 and MCP-1 (monocyte chemoattractant protein-1) in the kidney, but RDN had no effect on these measures. Thus, RDN is an effective treatment for hypertension in this model of CKD without further impairing renal function or altering the normal sympathetic reflex responses to various environmental stimuli.

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