Bone Mineral Content of Limb Bones of Male Weanling Rats Subjected to 30 and 60 Days of Simulated Increases in Body Weight

1985 ◽  
Vol 121 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Mark R.S. Simon ◽  
Kenneth R. Holmes ◽  
Aart M. Olsen
Keyword(s):  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Limb Bones ◽  
Weanling Rats

scholarly journals Explore Upper Limits of Bone Mineral Content And Density In Humans: A Study On Japanese Collegiate Sumo Wrestlers

2021 ◽  
Author(s):  
Taishi Midorikawa ◽  
Suguru Torii ◽  
Megumi Ohta ◽  
Shizuo Sakamoto
Keyword(s):  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Mineral Content ◽  
Mineral Density ◽  
Tissue Mass ◽  
X Ray ◽  
Upper Limit ◽  
Upper Limits

Abstract The purpose of this study was to explore the upper limit of total bone mineral content (BMC, kg) and bone mineral density (BMD, g/cm2) in humans by estimating body composition of Sumo wrestlers. A total of 54 male college Sumo wrestlers were recruited for the study and assigned to 2 groups according to body weight (middleweight, 85-115 kg, n = 23 and heavyweight, >115 kg, n = 31). BMC, BMD, fat mass and lean soft tissue mass (LSTM) were measured using dual-energy X-ray absorptiometry (DXA) for the total and appendicular regions. Heavyweight Sumo wrestlers had significantly greater body weight, fat mass, and LSTM compared to middleweight Sumo wrestlers. Mean total BMC was significantly larger in heavyweight than middleweight Sumo wrestlers, respectively (The highest value was 4.16 kg.). Total BMD was significantly higher in heavyweight compared to middleweight Sumo wrestlers (The highest value was 1.59 g/cm2.), and was significantly correlated with body weight, but not with fat mass and LSTM. Based on the present and previous studies, the upper limit of total BMC and BMD in humans with 150 kg bodyweight might be around 5.0 kg and 1.60 g/cm2.

Children with myelomeningocele have shorter stature, greater body weight, and lower bone mineral content than healthy children

1995 ◽  
Vol 15 (11) ◽  
pp. 1605-1611 ◽  
Author(s):  
Cesare Polito ◽  
Donatella Del Gaizo ◽  
Gaetano Di Manso ◽  
Donatella Stabile ◽  
Roberto Del Gado
Keyword(s):  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Healthy Children

scholarly journals The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats

2000 ◽  
Vol 165 (3) ◽  
pp. 569-577 ◽  
Author(s):  
J Svensson ◽  
S Lall ◽  
SL Dickson ◽  
BA Bengtsson ◽  
J Romer ◽  
...  
Keyword(s):  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Adult Female ◽  
Mineral Content ◽  
Female Rats ◽  
Volumetric Bmd ◽  
Ash Weight

Growth hormone (GH) is of importance for normal bone remodelling. A recent clinical study demonstrated that MK-677, a member of a class of GH secretagogues (GHSs), increases serum concentrations of biochemical markers of bone formation and bone resorption. The aim of the present study was to investigate whether the GHSs, ipamorelin (IPA) and GH-releasing peptide-6 (GHRP-6), increase bone mineral content (BMC) in young adult female rats. Thirteen-week-old female Sprague-Dawley rats were given IPA (0.5 mg/kg per day; n=7), GHRP-6 (0.5 mg/kg per day; n=8), GH (3.5 mg/kg per day; n=7), or vehicle administered continuously s.c. via osmotic minipumps for 12 weeks. The animals were followed in vivo by dual X-ray absorptiometry (DXA) measurements every 4th week. After the animals were killed, femurs were analysed in vitro by mid-diaphyseal peripheral quantitative computed tomography (pQCT) scans. After this, excised femurs and vertebrae L6 were analysed by the use of Archimedes' principle and by determinations of ash weights. All treatments increased body weight and total tibial and vertebral BMC measured by DXA in vivo compared with vehicle-treated controls. However, total BMC corrected for the increase in body weight (total BMC:body weight ratio) was unaffected. Tibial area bone mineral density (BMD, BMC/area) was increased, but total and vertebral area BMDs were unchanged. The pQCT measurements in vitro revealed that the increase in the cortical BMC was due to an increased cross-sectional bone area, whereas the cortical volumetric BMD was unchanged. Femur and vertebra L6 volumes were increased but no effect was seen on the volumetric BMDs as measured by Archimedes' principle. Ash weight was increased by all treatments, but the mineral concentration was unchanged. We conclude that treatment of adult female rats with the GHSs ipamorelin and GHRP-6 increases BMC as measured by DXA in vivo. The results of in vitro measurements using pQCT and Archimedes' principle, in addition to ash weight determinations, show that the increases in cortical and total BMC were due to an increased growth of the bones with increased bone dimensions, whereas the volumetric BMD was unchanged.

scholarly journals Body composition of piglets exhibiting different growth rates

2012 ◽  
Vol 55 (4) ◽  
pp. 356-363 ◽  
Author(s):  
A. D. Mitchell ◽  
T. G. Ramsay ◽  
T. J. Caperna ◽  
A. M. Scholz
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Growing Pigs ◽  
The Body ◽  
Body Composition Measurement ◽  
Total Body ◽  
Highly Correlated

Abstract. The growth and composition of the neonatal pig is of interest because of potential impact on subsequent growth and finally, composition at market weight. The purpose of this study was to compare at weaning the growth and body composition of the largest and smallest pigs from each of 38 litters. At weaning (27±1.7 d) the largest (9.3±1.1 kg) and smallest (6.2±1.5 kg) pigs were selected for body composition measurement by dual energy X-ray absorptiometry (DXA). The body composition of the largest pigs consisted of 38 % more fat, 32 % more lean, and 29 % more bone mineral content (P<0.001). However, when expressed as a percentage of body weight, there was no difference in the fat, lean or bone mineral content content of the two groups of pigs (P>0.05). A second study consisted of 12 pairs of pigs from 8 litters that were selected on the basis of having the same birth weight, but one pig out gaining the other by at least 50 g/day. At 21 days of age the selected pigs were scanned by DXA. For both groups combined, the correlation (r) between body weight and lean mass was 0.99, between body weight and fat mass it was 0.87, and between body weight at birth and body weight at weaning it was 0.56. The results of these studies revealed that, at weaning, the fastest and slowest growing pigs had similar proportions of fat, lean and bone mineral and, consistent with previous results, the rates of both fat and lean deposition were highly correlated (P<0.001) with total body growth rate.

Signalment differences in bone mineral content and bone mineral density in canine appendicular bones

2008 ◽  
Vol 21 (02) ◽  
pp. 147-151 ◽  
Author(s):  
S. Loebcke ◽  
M. Skalicky ◽  
S. Grampp ◽  
D. Lorinson ◽  
K. Lorinson
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Regions Of Interest ◽  
Middle Aged ◽  
Mineral Density ◽  
Fracture Development

SummaryThe objective was to determine signalment-related differences in bone mineral content (BMC) and bone mineral density (BMD) in dogs. Unilateral appendicular bones were harvested from 62 canine cadavers. Middiaphyseal regions of interest (ROIs) were scanned using a Hologic® DXA device Braincon, Vienna, Austria). BMC and BMD were calculated within this region. Middle-aged dogs (3 . 10 years) revealed the highest BMC and BMD levels. Mean BMC and BMD were higher in males compared to females. Furthermore, bodyweight of the male dogs was significantly higher compared to the females (P<0.0001). Body weight and bone length were significantly associated with BMC and BMD (P.0.023) in all bones but the radius. These data suggest that BMC and BMD appear to be highest in male large-breed dogs with a body weight greater than 30 kg. These results may help determine risk factors in fracture development and healing.

Influence of anthropometric parameters on assessment of paediatric bone mineral density and bone mineral content

2013 ◽  
Author(s):  
N Hangartner Thomas ◽  
F Short David ◽  
Gilsanz Vicente ◽  
J Kalkwarf Heidi ◽  
M Lappe Joan ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Mineral Density ◽  
Anthropometric Parameters
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