Premature death of Purkinje cells following low-level X-ray irradiation during embryonic development

1978 ◽  
Vol 101 (3) ◽  
pp. 225-233 ◽  
Author(s):  
Gopal D. Das
2020 ◽  
Vol 501 (1) ◽  
pp. 1453-1462
Author(s):  
A S Parikh ◽  
N Degenaar ◽  
J V Hernández Santisteban ◽  
R Wijnands ◽  
I Psaradaki ◽  
...  

ABSTRACT The accretion behaviour in low-mass X-ray binaries (LMXBs) at low luminosities, especially at <1034 erg s−1, is not well known. This is an important regime to study to obtain a complete understanding of the accretion process in LMXBs, and to determine if systems that host neutron stars with accretion-heated crusts can be used probe the physics of dense matter (which requires their quiescent thermal emission to be uncontaminated by residual accretion). Here, we examine ultraviolet (UV) and X-ray data obtained when EXO 0748–676, a crust-cooling source, was in quiescence. Our Hubble Space Telescope spectroscopy observations do not detect the far-UV continuum emission, but do reveal one strong emission line, C iv. The line is relatively broad (≳3500 km s−1), which could indicate that it results from an outflow such as a pulsar wind. By studying several epochs of X-ray and near-UV data obtained with XMM–Newton, we find no clear indication that the emission in the two wavebands is connected. Moreover, the luminosity ratio of LX/LUV ≳ 100 is much higher than that observed from neutron star LMXBs that exhibit low-level accretion in quiescence. Taken together, this suggests that the UV and X-ray emission of EXO 0748–676 may have different origins, and that thermal emission from crust-cooling of the neutron star, rather than ongoing low-level accretion, may be dominating the observed quiescent X-ray flux evolution of this LMXB.


Reproduction ◽  
2013 ◽  
Vol 145 (4) ◽  
pp. 421-437 ◽  
Author(s):  
Pouneh Maraghechi ◽  
László Hiripi ◽  
Gábor Tóth ◽  
Babett Bontovics ◽  
Zsuzsanna Bősze ◽  
...  

MicroRNAs (miRNAs) are small non-coding RNAs that regulate multiple biological processes. Increasing experimental evidence implies an important regulatory role of miRNAs during embryonic development and in embryonic stem (ES) cell biology. In the current study, we have described and analyzed the expression profile of pluripotency-associated miRNAs in rabbit embryos and ES-like cells. The rabbit specific ocu-miR-302 and ocu-miR-290 clusters, and three homologs of the human C19MC cluster (ocu-miR-512, ocu-miR-520e, and ocu-miR-498) were identified in rabbit preimplantation embryos and ES-like cells. The ocu-miR-302 cluster was highly similar to its human homolog, while ocu-miR-290 revealed a low level of evolutionary conservation with its mouse homologous cluster. The expression of the ocu-miR-302 cluster began at the 3.5 days post-coitum early blastocyst stage and they stayed highly expressed in rabbit ES-like cells. In contrast, a high expression level of the ocu-miR-290 cluster was detected during preimplantation embryonic development, but a low level of expression was found in rabbit ES-like cells. Differential expression of the ocu-miR-302 cluster and ocu-miR-512 miRNA was detected in rabbit trophoblast and embryoblast. We also found that Lefty has two potential target sites in its 3′UTR for ocu-miR-302a and its expression level increased upon ocu-miR-302a inhibition. We suggest that the expression of the ocu-miR-302 cluster is characteristic of the rabbit ES-like cell, while the ocu-miR-290 cluster may play a crucial role during early embryonic development. This study presents the first identification, to our knowledge, of pluripotency-associated miRNAs in rabbit preimplantation embryos and ES-like cells, which can open up new avenues to investigate the regulatory function of ocu-miRNAs in embryonic development and stem cell biology.


1988 ◽  
Vol 32 ◽  
pp. 251-253 ◽  
Author(s):  
F. Hegedüs ◽  
P. Winkler

A special measurement technique has been developed to measure very low level iodine concentrations. The gas and water samples to be analysed are taken from the POSEIDON facility at PSI where retention of iodine in water pools in conjunction with light water reactor safety analysis is under investigation. The amount of iodine was measured by means of a Total Reflectance X-Ray Spectrometer (TXRF).


1994 ◽  
Vol 46 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Jyotirmoy Chatterjee ◽  
Kuntala De ◽  
S. K. Basu ◽  
A. K. Das
Keyword(s):  
Rat Skin ◽  
X Ray ◽  

1987 ◽  
Vol 65 ◽  
pp. 273 ◽  
Author(s):  
Carol W. Ambruster ◽  
Salvatore Sciortino ◽  
L. Golub
Keyword(s):  
X Ray ◽  

1991 ◽  
Vol 35 (B) ◽  
pp. 965-967
Author(s):  
F. Hegedus ◽  
P. Winkler

AbstractThe Total Reflection X-Ray Fluorescence method was used to detect low level (ppb) uranium concentration in water.


1995 ◽  
Author(s):  
Marc Nantel ◽  
Annie Klisnick ◽  
Gerard Jamelot ◽  
P. B. Holden ◽  
Pierre Jaegle ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document