Histochemical localization of acetylcholinesterase enzyme in the ‘limbic system’ of the brain of the cebus monkey (Cebus apella)

1973 ◽  
Vol 84 (2) ◽  
pp. 202-223 ◽  
Author(s):  
Makram Girgis
Author(s):  
Michael Trimble

This chapter discusses the clinical necessity from which the intersection of neurology and psychiatry arose, exploring different eras and their associated intellectual milestones in order to understand the historical framework of contemporary neuropsychiatry. Identifying Hippocrates’ original acknowledgement of the relation of the human brain to epilepsy as a start point, the historical development of the field is traced. This encompasses Thomas Willis and his nascent descriptions of the limbic system, the philosophical and alchemical strides of the Enlightenment, and the motivations behind the Romantic era attempts to understand the brain. It then follows the growth of the field through the turn of the twentieth century, in spite of the prominence of psychoanalysis and the idea of the brainless mind, and finally the understanding of the ‘integrated action’ of the body and nervous system, which led to the integration of psychiatry and neurology, allowing for the first neuropsychiatric examinations of epilepsy.


2010 ◽  
Vol 4 (3) ◽  
pp. 181-187 ◽  
Author(s):  
Kellen Christina Malheiros Borges ◽  
Jussara Rocha Ferreira ◽  
Leonardo Ferreira Caixeta

Abstract The organization of the prefrontal cortex can hold important clues to understanding its functioning. The Cebus apella present cerebral particularities and behavioral and cognitive flexibility, possessing abilities that demonstrate an overlap with those of big primates. Objectives: To provide evidence of correlations between anatomical particularities of the brain areas analyzed and some cognitive abilities previously described in these simians. Methods: The relative size of the cerebral hemispheres and prefrontal areas (PFA) were measured using a Universal caliper, in 24 hemispheres of C. apella fixed with 10% formaldehyde and kept in 70% alcoholic solution. Results: Data gathered allowed the calculation of the approximate volume (cm3) of the areas under study: right antimere 35.2 cm3 (±5.3), left antimere 31.3 cm3 (±5.4) and of the left PFA 6.0 cm3 (±1.5) and right PFA 6.9 cm3 (±1.7). Conclusions: We concluded that the PFA represents about 20% of the cerebral volume of this primate. No significant differences were found in the antimeres in terms of volume and area of the hemispheres and likewise for the PFA. These animals have a proportionally bigger brain than that of other neotropical primates in the literature. This allows us to infer that the frontal lobe of C. apella is also larger; possibly related to its maturity and developed cognitive functions indicative of the culture transfers characteristic of this species.


Author(s):  
C. A. Nagle ◽  
J. H. Denari
Keyword(s):  

Author(s):  
Changwon Kim ◽  
Reza Langari

This paper presents the application of a novel intelligent control strategy for lane change maneuvers in highway environment. The lateral dynamics of a vehicle with and without wind disturbance are derived and utilized to implement a neuromophic controller based on the brain limbic system. To show the robustness of the proposed controller, several disturbance conditions including wind, uncertainty in the cornering stiffness, and changes in the vehicle mass, are investigated. To demonstrate the performance of the suggested strategy, the simulation results of the proposed method were compared with the human driver model based control scheme, which has been discussed in the literature. The simulation results demonstrate the superiority of the proposed controller in energy efficiency, driving comfort, and robustness.


1972 ◽  
Vol 34 (3) ◽  
pp. 827-833 ◽  
Author(s):  
Robert J. Harmon ◽  
Robert N. Emde

A microcephalic human newborn exhibited a repertoire of spontaneous REM behaviors, including REM smiling, at rates characteristic of a normal newborn comparison group. Cyclical alternations between behavioral REM and non-REM states were also documented. A detailed post-mortem examination supported an inference that this infant had severely impaired functioning of cerebral cortex and limbic system during its brief postuterine life. The findings support a tentative conclusion that the observed spontaneous REM behaviors are mediated through the brain stem and that cerebral structures, including the limbic system, are not necessary for this mediation. The findings are also consistent with previous evidence that the seat of organization of REM and non-REM sleep is in the brain stem.


1980 ◽  
Vol 108 (2) ◽  
pp. 175-183 ◽  
Author(s):  
Wang Shih-chang ◽  
M. Girgis
Keyword(s):  

1985 ◽  
Vol 100 (4) ◽  
pp. 1333-1335 ◽  
Author(s):  
T. A. Devyatkina ◽  
L. M. Tarasenko ◽  
L. E. Bobyreva ◽  
N. G. Sergienko ◽  
O. N. Voskresenskii

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