Adenosine Deaminase Genetic Polymorphism and Coronary Artery Disease

Cardiology ◽  
2009 ◽  
Vol 112 (1) ◽  
pp. 74-75 ◽  
Author(s):  
Maria Banci ◽  
Patrizia Saccucci ◽  
Federica D’Annibale ◽  
Alessandro Dofcaci ◽  
Gianfranco Trionfera ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Genetic Polymorphism ◽  
Adenosine Deaminase ◽  
Artery Disease

scholarly journals e0055 Relationship between Genetic polymorphism of cytochrome P4502C19 and coronary artery disease in Xinjiang Uigur population

Heart ◽  
2010 ◽  
Vol 96 (Suppl 3) ◽  
pp. A18-A18
Author(s):  
Y. Yining ◽  
M. Yitong ◽  
W. Xinlei ◽  
L. Fen ◽  
X. Xie
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Genetic Polymorphism ◽  
Artery Disease

P40 Genetic polymorphism g455a on fibrinogen chain B gene is not a risk factor for women with coronary artery disease: effects on pre-thrombotic state

2009 ◽  
Vol 123 ◽  
pp. S151
Author(s):  
M. Kozanitou ◽  
N. Papageorgiou ◽  
A. Vlachopoulou ◽  
D. Tousoulis ◽  
C. Antoniadis ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Genetic Polymorphism ◽  
Artery Disease

Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene

2014 ◽  
Vol 69 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Patrizia Saccucci ◽  
Agnieszka Binczak-Kuleta ◽  
Maria Banci ◽  
Maja Krzysztalowska ◽  
Alessandro Dofcaci ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Adenosine Deaminase ◽  
Artery Disease

Genetic polymorphism of methylenetetrahydrofolate reductase (MTHFR) and coronary artery disease

2011 ◽  
Vol 9 (04) ◽  
pp. 205-207
Author(s):  
Fausi Rassoul ◽  
Volker Richter ◽  
Thomas Kuntze ◽  
Friedrich-Wilhelm Mohr ◽  
Jürgen Geisel ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Genetic Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Artery Disease

scholarly journals Serum adenosine deaminase activity and coronary artery disease: a retrospective case-control study based on 9929 participants

2019 ◽  
Vol 10 ◽  
pp. 204062231989153
Author(s):  
Chao Xuan ◽  
Qing-Wu Tian ◽  
Shao-Yan Zhang ◽  
Hui Li ◽  
Ting-Ting Tian ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Adenosine Deaminase ◽  
Case Control Study ◽  
Case Control ◽  
The Body ◽  
Retrospective Case ◽  
Adenosine Deaminase Activity ◽  
Artery Disease ◽  
Control Study

Background: Adenosine deaminase (ADA) regulates purine metabolism through the conversion of adenosine to uric acid (UA). Adenosine and UA are closely associated with cardiovascular events, but the correlation between serum ADA activity and coronary artery disease (CAD) has not been defined. Methods: We performed a hospital-based retrospective case-control study that included a total of 5212 patients with CAD and 4717 sex- and age-matched controls. The serum activity of ADA was determined by peroxidase assays in an automatic biochemistry analyzer. Results: Serum ADA activity in the CAD group (10.08 ± 3.57 U/l) was significantly lower than that of the control group (11.71 ± 4.20 U/l, p < 0.001). After adjusting for conventional factors, serum ADA activity negatively correlated with the presence of CAD (odds ratio = 0.852, 95% confidence interval: 0.839–0.865, p < 0.001). Among the patients with CAD, serum ADA activity was lowest in patients with myocardial infarction (MI; 9.77 ± 3.80 U/l). Diabetes mellitus and hypertension increased the serum ADA activity in CAD patients. Conclusions: Serum ADA activity is significantly attenuated in patients with CAD, particularly in MI. We propose a mechanism by which the body maintains adenosine levels to protect the cardiovascular system in the event of CAD.

scholarly journals A Genetic Polymorphism in RBP4 Is Associated with Coronary Artery Disease

2014 ◽  
Vol 15 (12) ◽  
pp. 22309-22319 ◽  
Author(s):  
Ke Wan ◽  
Jianxun Zhao ◽  
Ying Deng ◽  
Xi Chen ◽  
Qing Zhang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Genetic Polymorphism ◽  
Artery Disease
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