Brilliant Blue in Vitreoretinal Surgery

Author(s):  
Hiroshi Enaida ◽  
Tatsuro Ishibashi
2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Takahiko Hayashi ◽  
Kentaro Yuda ◽  
Itaru Oyakawa ◽  
Naoko Kato

Vital staining of the endothelial graft is essential during Descemet’s membrane endothelial keratoplasty (DMEK) to ensure surgical success. DMEK surgeons worldwide commonly use trypan blue (TB) to this end. However, TB may exert toxic effects on both the cornea and retina. Recently, Brilliant Blue G (BBG) has become recognized as an alternative stain for use during vitreoretinal surgery; BBG is associated with lower levels of toxicity. We retrospectively analyzed the utility of BBG staining during DMEK. We used 0.1% (w/v) BBG to stain the DMEK grafts of 12 patients. We evaluated the best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), and endothelial cell density (ECD) before and 3 and 6 months after surgery. BBG was effective in terms of graft visualization during DMEK. The BSCVA (log  MAR) improved from0.99±0.57to0.01±0.07(p<0.05). The CCT decreased from720.3±58.1 μm preoperatively to511.5±50.6 μm at 6 months postoperatively (p=0.0001). The ECD decreased from2,754±296 cells/mm2to1,708±426 cells/mm2at 6 months postoperatively (p<0.001). The ECD loss was37.9±16.3%. The outcomes using BBG were comparable to those of earlier reports that employed TB; thus, BBG may be a viable alternative to TB.


2020 ◽  
Vol Volume 14 ◽  
pp. 2307-2309
Author(s):  
Fares Antaki ◽  
Daniel Milad ◽  
Simon Javidi ◽  
Ali Dirani

Soft Matter ◽  
2021 ◽  
Vol 17 (6) ◽  
pp. 1463-1467
Author(s):  
Xinxian Ma ◽  
Bo Qiao ◽  
Yingshan Lai ◽  
Yutao Geng ◽  
Jinlong Le ◽  
...  

Gelator (G1) solution reveals brilliant blue light upon mixing with Mg2+; this blue light can be erased using saliva or CO32−. Based on this characteristic, a smart erasable writable material was prepared.


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