Imatinib Mesylate Treatment for Advanced Gastrointestinal Stromal Tumor: A Pilot Study Focusing on Patients Experiencing Sole Liver Metastasis after a Prior Radical Resection

Oncology ◽  
2007 ◽  
Vol 73 (5-6) ◽  
pp. 324-327 ◽  
Author(s):  
Jiang Zhu ◽  
Yan Wang ◽  
Mei Hou ◽  
Hui Yan Li ◽  
Jie Zhang
Keyword(s):  
Pilot Study ◽  
Liver Metastasis ◽  
Gastrointestinal Stromal Tumor ◽  
Imatinib Mesylate ◽  
Radical Resection ◽  
Stromal Tumor

scholarly journals A Case of Liver Metastasis from Small Intestinal Gastrointestinal Stromal Tumor 25 Years after Surgery including Autopsy Findings

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yuichi Takano ◽  
Masataka Yamawaki ◽  
Jun Noda ◽  
Tetsushi Azami ◽  
Takahiro Kobayashi ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Gastrointestinal Stromal Tumor ◽  
Liver Tumors ◽  
Lung Metastases ◽  
Epigastric Pain ◽  
Percutaneous Biopsy ◽  
Radical Resection ◽  
Multiple Organ ◽  
Massive Hemorrhage ◽  
Stromal Tumor

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the digestive tract. Recurrences may occur even after radical resection; however, recurrence later than 10 years after surgery is rare. We report a case of GIST with recurrence of liver metastasis 25 years after surgery. A 56-year-old man complained of sudden epigastric pain and was transferred to the emergency department. He had undergone partial resection of the small intestine for leiomyosarcoma 25 years previously. Abdominal computed tomography showed multiple liver tumors with massive hemorrhage. Ultrasound-guided percutaneous biopsy was performed for the 15-mm hepatic tumor in segment 2. Pathological findings revealed proliferation of spindle-shaped atypical cells, and immunostaining for c-kit and CD34 was both positive; the patient was therefore diagnosed with GIST. He then underwent chemotherapy for 7 years but died of multiple organ failure due to GIST. Autopsy revealed GIST occupying the entire liver with peritoneal dissemination, and minute lung metastases that could not be identified by CT were also detected. This case is interesting in considering the recurrence of GIST, and we will report it together with the literature review.

scholarly journals Hepatectomy for liver metastasis from gastrointestinal stromal tumor in the era of imatinib mesylate: a case series study

2017 ◽  
Vol 6 (3) ◽  
pp. 121-125
Author(s):  
Norio Kawamura ◽  
Toshiya Kamiyama ◽  
Hideki Yokoo ◽  
Tatsuhiko Kakisaka ◽  
Tatsuya Orimo ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Gastrointestinal Stromal Tumor ◽  
Imatinib Mesylate ◽  
Case Series ◽  
Stromal Tumor ◽  
Case Series Study ◽  
Series Study

scholarly journals A liver metastasis 7 years after resection of a low-risk duodenal gastrointestinal stromal tumor

2021 ◽  
Author(s):  
Masashi Inoue ◽  
Masayuki Shishida ◽  
Atsuhiro Watanabe ◽  
Ryujiro Kajikawa ◽  
Ryotaro Kajiwara ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Gastrointestinal Stromal Tumor ◽  
Low Risk ◽  
Stromal Tumor

scholarly journals The Merendino procedure following preoperative imatinib mesylate for locally advanced gastrointestinal stromal tumor of the esophagogastric junction

2008 ◽  
Vol 6 (1) ◽  
pp. 37 ◽  
Author(s):  
Wilko I Staiger ◽  
Ulrich Ronellenfitsch ◽  
Georg Kaehler ◽  
Hans Schildhaus ◽  
Antonia Dimitrakopoulou-Strauss ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Imatinib Mesylate ◽  
Esophagogastric Junction ◽  
Locally Advanced ◽  
Stromal Tumor ◽  
Merendino Procedure

scholarly journals A Hemodialysis Patient with Primary Extra-gastrointestinal Stromal Tumor: Favorable Outcome with Imatinib Mesylate

2012 ◽  
Vol 51 (12) ◽  
pp. 1561-1565 ◽  
Author(s):  
Yukihiro Wada ◽  
Hiroaki Ogata ◽  
Shiho Misawa ◽  
Akira Shimada ◽  
Eriko Kinugasa
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Imatinib Mesylate ◽  
Hemodialysis Patient ◽  
Stromal Tumor ◽  
Favorable Outcome
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