Cytological and Cyst Fluid Analysis of Small (≤3 cm) Branch Duct Intraductal Papillary Mucinous Neoplasms Adds Value to Patient Management Decisions

Pancreatology ◽  
2008 ◽  
Vol 8 (3) ◽  
pp. 277-284 ◽  
Author(s):  
Martha Bishop Pitman ◽  
Paul J. Michaels ◽  
Vikram Deshpande ◽  
William R. Brugge ◽  
Brenna C. Bounds
Keyword(s):  
Patient Management ◽  
Cyst Fluid ◽  
Management Decisions ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Fluid Analysis ◽  
Mucinous Neoplasms

scholarly journals Stratifying Intraductal Papillary Mucinous Neoplasms by Cyst Fluid Analysis: Present and Future

2020 ◽  
Vol 21 (3) ◽  
pp. 1147
Author(s):  
Scarlett Hao ◽  
Caitlin Takahashi ◽  
Rebecca A. Snyder ◽  
Alexander A. Parikh
Keyword(s):  
Significant Proportion ◽  
Cyst Fluid ◽  
Low Risk ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Radiographic Findings ◽  
Genetic Sequencing ◽  
Perioperative Morbidity ◽  
Fluid Analysis ◽  
Mucinous Neoplasms ◽  
Risk Of Malignancy

A significant proportion of patients with intraductal papillary mucinous neoplasms (IPMNs) undergo surgical resection in order to prevent or treat pancreatic cancer at the risk of significant perioperative morbidity. Efforts have been made to stratify the potential risk of malignancy based on the clinical and radiographic features of IPMN to delineate which cysts warrant resection versus observation. An analysis of the cyst fluid obtained by preoperative endoscopic examination appears to be correlative of cyst type and risk, whereas serum markers and radiographic findings have not yet reached a level of sensitivity or specificity that proves they are clinically meaningful. In this review, we investigate the current cyst fluid analysis studies and present those that have shown promise in effectively stratifying high-risk versus low-risk lesions. While new cyst fluid markers continue to be identified, additional efforts in testing panels and marker composites in conjunction with clinical algorithms have also shown promise in distinguishing dysplasia and the risk of malignancy. These should be tested prospectively in order to determine their role in guiding the surveillance of low-risk lesions and to evaluate the new markers detected by proteomics and genetic sequencing.

scholarly journals Cyst Fluid Analysis in Pancreatic Intraductal Papillary Mucinous Neoplasms

2016 ◽  
Vol 22 (20) ◽  
pp. 4966-4967 ◽  
Author(s):  
Peter J. Allen ◽  
Christine A. Iacobuzio-Donahue ◽  
David S. Klimstra
Keyword(s):  
Cyst Fluid ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Fluid Analysis ◽  
Mucinous Neoplasms

Should all branch-duct intraductal papillary mucinous neoplasms be resected?

2015 ◽  
Vol 209 (3) ◽  
pp. 478-482 ◽  
Author(s):  
Jennifer K. Plichta ◽  
Kristen Ban ◽  
Zachary Fridirici ◽  
Anjali S. Godambe ◽  
Sherri Yong ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Mucinous Neoplasms

BRANCH DUCT INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS OF THE PANCREAS (IPMNS)

Pancreas ◽  
2006 ◽  
Vol 33 (4) ◽  
pp. 493 ◽  
Author(s):  
J. R. Rodr??guez ◽  
R. Salvia ◽  
S. Crippa ◽  
C. Bassi ◽  
P. Pederzoli ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Mucinous Neoplasms

Diagnostic Accuracy of Preoperative Imaging for Differentiation of Branch Duct Versus Mixed Duct Intraductal Papillary Mucinous Neoplasms

Pancreas ◽  
2018 ◽  
Vol 47 (5) ◽  
pp. 556-560 ◽  
Author(s):  
Emmanuel E. Ugbarugba ◽  
Carmen Grieco ◽  
Phil A. Hart ◽  
Feng Li ◽  
Brett Sklaw ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Preoperative Imaging ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Mucinous Neoplasms

Progression vs Cyst Stability of Branch-Duct Intraductal Papillary Mucinous Neoplasms After Observation and Surgery

JAMA Surgery ◽  
2021 ◽  
Author(s):  
Giovanni Marchegiani ◽  
Tommaso Pollini ◽  
Stefano Andrianello ◽  
Giorgia Tomasoni ◽  
Marco Biancotto ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Mucinous Neoplasms
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