Regional mapping of the human platelet-activating factor receptor gene (PTAFR) to 1 p35→p34.3 by fluorescence in situ hybridization

1996 ◽  
Vol 72 (2-3) ◽  
pp. 205-207 ◽  
Author(s):  
P.B. Chase ◽  
J.-M. Yang ◽  
F.H. Thompson ◽  
M. Halonen ◽  
J.W. Regan
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Human Platelet ◽  
Receptor Gene ◽  
Platelet Activating Factor ◽  
Regional Mapping ◽  
Platelet Activating Factor Receptor

Assignment of the human ubiquitous receptor gene (UNR) to 19q13.3 using fluorescence in situ hybridization

Genomics ◽  
1995 ◽  
Vol 26 (1) ◽  
pp. 166-168 ◽  
Author(s):  
Michelle M. Le Beau ◽  
Ching Song ◽  
Elizabeth M. Davis ◽  
Richard A. Hiipakka ◽  
John M. Kokontis ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Receptor Gene

scholarly journals A murine platelet-activating factor receptor gene: cloning, chromosomal localization and up-regulation of expression by lipopolysaccharide in peritoneal resident macrophages

1996 ◽  
Vol 314 (2) ◽  
pp. 671-678 ◽  
Author(s):  
Satoshi ISHII ◽  
Yoichi MATSUDA ◽  
Motonao NAKAMURA ◽  
Iwao WAGA ◽  
Kazuhiko KUME ◽  
...  
Keyword(s):  
Lipid A ◽  
Receptor Gene ◽  
Platelet Activating Factor ◽  
Peritoneal Macrophages ◽  
Regulation Of Expression ◽  
Gene Encoding ◽  
Platelet Activating Factor Receptor ◽  
Factor Α ◽  
Necrosis Factor

A murine gene encoding a platelet-activating factor receptor (PAFR) was cloned. The gene was mapped to a region of the D2.2 band of chromosome 4 both by fluorescence in situ hybridization and by molecular linkage analysis. Northern blot analysis showed a high expression of the PAFR message in peritoneal macrophages. When C3H/HeN macrophages were treated with bacterial lipopolysaccharide (LPS) or synthetic lipid A, the PAFR gene expression was induced. Bacterial LPS, but not lipid A, induced the level of PAFR mRNA in LPS-unresponsive C3H/HeJ macrophages. These induction patterns were parallel to those of tumour necrosis factor-α mRNA. Thus the PAFR in macrophages is important in LPS-induced pathologies.

Regional mapping of the human NSP gene to chromosome region 14q21→q22 by fluorescence in situ hybridization analysis

1994 ◽  
Vol 66 (1) ◽  
pp. 48-50 ◽  
Author(s):  
P.F.J. Kools ◽  
A.J.M. Roebroek ◽  
H.J.K. Van deVelde ◽  
P. Marynen ◽  
J. Bullerdiek ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Chromosome Region ◽  
Hybridization Analysis ◽  
Regional Mapping
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