Isolation and regional localization of 25 anonymous DNA probes on a chromosome 13 hybrid panel

1991 ◽  
Vol 57 (2-3) ◽  
pp. 87-90 ◽  
Author(s):  
R.H.J. Houwen ◽  
S.E. Pautler ◽  
J.A. Barwell ◽  
K. Arden ◽  
J.A. Buchanan ◽  
...  
Keyword(s):  
Dna Probes ◽  
Regional Localization ◽  
Chromosome 13

An Integrated Map of Human Chromosome 13 Allowing Regional Localization of Genetic Markers

1995 ◽  
Vol 3 (3) ◽  
pp. 180-187 ◽  
Author(s):  
R. Frank Kooy ◽  
Albert Wijngaard ◽  
Edwin Verlind ◽  
Hans Scheffer ◽  
Charles Buys
Keyword(s):  
Human Chromosome ◽  
Genetic Markers ◽  
Regional Localization ◽  
Integrated Map ◽  
Chromosome 13

Mapping the Y chromosome

Development ◽  
1987 ◽  
Vol 101 (Supplement) ◽  
pp. 39-39
Author(s):  
P. N. Goodfellow
Keyword(s):  
Sex Determination ◽  
Y Chromosome ◽  
X Chromosome ◽  
Dna Probes ◽  
Genetic Maps ◽  
Variable Amount ◽  
Regional Localization ◽  
Y Chromosomes ◽  
Xx Males ◽  
Human Y Chromosome

DNA probes isolated from the human Y chromosome have been used to resolve two fundamental problems concerning the biology of sex determination in man. Coincidentally, resolution of these problems has generated genetic maps of the short arm of the human Y chromosome and has allowed the regional localization of TDF. The first problem to be solved was the origin of XX males (de la Chapelle, this symposium): the majority of XX males are caused by a telomeric exchange between the X and Y chromosomes that results in TDF and a variable amount of Y-derived material being transferred to the X chromosome. The differing amounts of Y-derived material present in XX males has been used as the basis of a ‘deletion’ map of the Y chromosome (Müller; Ferguson-Smith & Affara; this symposium).

Regional Localization of 32 NotI-HindIII Fragments from a Human Chromosome 13 Library by a Somatic Cell Hybrid Panel and in Situ Hybridization

Genomics ◽  
1993 ◽  
Vol 16 (2) ◽  
pp. 355-360 ◽  
Author(s):  
Dorothy Warburton ◽  
Ming-Tsung Yu ◽  
Umadevi Tantravahi ◽  
Carolyn Lee ◽  
Eftihia Cayanis ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Human Chromosome ◽  
Somatic Cell ◽  
Cell Hybrid ◽  
Somatic Cell Hybrid ◽  
Somatic Cell Hybrid Panel ◽  
Regional Localization ◽  
Chromosome 13

scholarly journals Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma

Blood ◽  
2005 ◽  
Vol 106 (10) ◽  
pp. 3553-3558 ◽  
Author(s):  
Gordon W. Dewald ◽  
Terry Therneau ◽  
Dirk Larson ◽  
You Kyoung Lee ◽  
Stephanie Fink ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Patient Survival ◽  
Dna Probes ◽  
Poor Survival ◽  
Interphase Nuclei ◽  
Chromosome Anomalies ◽  
Chromosome 13 ◽  
Interphase Cells ◽  
Conventional Cytogenetics ◽  
Relationship Of

AbstractThe clinical efficacy of evaluating genetic anomalies in metaphase cells versus interphase nuclei for multiple myeloma (MM) is poorly understood. Therefore, survival for 154 patients with newly diagnosed untreated MM was compared with results from analysis of metaphase and interphase cells. Metaphases were studied by conventional cytogenetics and fluorescent-labeled DNA probes (fluorescence in situ hybridization [FISH]), whereas inter-phase nuclei were evaluated only by FISH. All FISH studies were done using DNA probes to detect t(4;14)(p16;q32), t(11;14)(q13;q32), t(14;16)(q32;q23), del(17) (p13.1), and chromosome 13 anomalies. Metaphases were abnormal by cytogenetics and/or metaphase FISH in 61 (40%) patients. Abnormal interphase nuclei were observed in 133 (86%) patients, including each patient with abnormal metaphases. FISH was a necessary adjunct to cytogenetics to detect t(4;14) and t(14;16) in metaphase cells. Patient survival was especially poor for patients with greater than 50% abnormal interphase nuclei, although this result was more likely due to level of plasma cells than specific chromosome anomalies. For metaphase data, patients with t(4;14), t(14;16), del(17) (p13.1), and/or chromosome 13 anomalies (primarily monosomy 13) had poor survival. A different outcome was observed for interphase data as patients with t(4;14) or t(14;16) had poor survival, whereas patients with chromosome 13 anomalies had intermediate survival: interphase FISH did not substitute for metaphase analysis.

The porcine intestinal receptor forEscherichia coliK88ab, K88ac: regional localization on chromosome 13 and influence of IgG response to the K88 antigen

1995 ◽  
Vol 26 (4) ◽  
pp. 237-242 ◽  
Author(s):  
I Edfors-Lilja ◽  
U Gustafsson ◽  
Y Duval-Iflah ◽  
H Ellergren ◽  
M Johansson ◽  
...  
Keyword(s):  
Regional Localization ◽  
Chromosome 13

Regional localization of DNA probes on the short arm of chromosome 11 using aniridia-Wilms' tumor-associated deletions

1987 ◽  
Vol 75 (2) ◽  
pp. 180-187 ◽  
Author(s):  
M. Mannens ◽  
R. M. Slater ◽  
C. Heyting ◽  
A. Geurts van Kessel ◽  
E. Goedde-Salz ◽  
...  
Keyword(s):  
Wilms Tumor ◽  
Dna Probes ◽  
Chromosome 11 ◽  
Regional Localization

Development of pattern recognition based on the nanosheet-DNA probes and an extendible DNA library

The Analyst ◽  
2021 ◽  
Author(s):  
Jiawei Qi ◽  
Pinhua Rao ◽  
Lele Wang ◽  
Li Xu ◽  
Yanli Wen ◽  
...  
Keyword(s):  
Pattern Recognition ◽  
High Throughput ◽  
Analysis Data ◽  
Dna Probes ◽  
High Throughput Analysis ◽  
Throughput Analysis ◽  
Dna Library ◽  
Array Sensing

Pattern recognition, also called “array sensing” is a recognition strategy with a wide and expandable analysis range, based on the high-throughput analysis data. In this work, we constructed a sensor...

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