Localization of the human myelin basic protein gene (MBP) to region 18q22→qter by in situ hybridization

1985 ◽  
Vol 39 (4) ◽  
pp. 246-249 ◽  
Author(s):  
D.F. Saxe ◽  
N. Takahashi ◽  
L. Hood ◽  
M.I. Simon
Keyword(s):  
In Situ Hybridization ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Protein Gene ◽  
Myelin Basic Protein Gene

scholarly journals Expression of myelin basic protein gene in the developing rat brain as revealed by in situ hybridization.

1986 ◽  
Vol 34 (4) ◽  
pp. 467-473 ◽  
Author(s):  
K Kristensson ◽  
N K Zeller ◽  
M E Dubois-Dalcq ◽  
R A Lazzarini
Keyword(s):  
In Situ Hybridization ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Seventh Cranial Nerve ◽  
Myelin Basic Protein Gene ◽  
Old Rats ◽  
Developing Rat ◽  
The Brain ◽  
Specific Mrna

The developmental program controlling the expression of myelin basic protein (MBP) gene was studied in the rat using the technique of in situ hybridization. A 35S-labeled cDNA clone of mouse MBP encoding an amino acid sequence present in all four of the major forms of rodent MBP was used. The probe hybridized to the tracts of white matter with different intensities, depending on the age of the animal and the region of the brain examined. In the medulla oblongata, maximal hybridization was found in 5- and 7-day-old rats and was confined to the tectospinal tracts, fibers of the seventh cranial nerve, and the spinocerebellar tracts. By 12 days the amount of MBP mRNA had decreased in these areas. In the cerebrum, the greatest amount of MBP mRNA was observed in 17-day-old rats in the radiations of the corpus callosum. Thereafter, the levels decreased but could still be observed in the adult animals. Thus, using this technique, we have been able to demonstrate that the level of MBP-specific mRNA correlates closely with the development of myelin in different regions of the brain.

Myelin basic protein gene-related protein (MGRP)

1992 ◽  
Vol 17 ◽  
pp. 139
Author(s):  
Mitsuko Sugano ◽  
Tatsunori Seki ◽  
Hiroki Nakae
Keyword(s):  
Myelin Basic Protein ◽  
Basic Protein ◽  
Protein Gene ◽  
Related Protein ◽  
Myelin Basic Protein Gene

Linkage mapping of the porcine myelin basic protein gene to chromosome 11

2005 ◽  
Vol 36 (2) ◽  
pp. 163-164
Author(s):  
J. G. Kim ◽  
D. Nonneman ◽  
J. L. Vallet ◽  
G. A. Rohrer ◽  
R. K. Christenson
Keyword(s):  
Myelin Basic Protein ◽  
Linkage Mapping ◽  
Basic Protein ◽  
Protein Gene ◽  
Chromosome 11 ◽  
Myelin Basic Protein Gene

Expression of the Myelin Basic Protein Gene in Transgenic Mice Expressing Human Neurotropic Virus, JCV, Early Protein

Virology ◽  
1994 ◽  
Vol 202 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Susan Haas ◽  
Nasreen S. Haque ◽  
Alan H. Beggs ◽  
Kamel Khalili ◽  
Robert L. Knobler ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Protein Gene ◽  
Neurotropic Virus ◽  
Early Protein ◽  
Myelin Basic Protein Gene
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