Current Guidelines for the Diagnosis and Treatment of Celiac Disease

Author(s):  
Ricardo A. Caicedo ◽  
Ivor D. Hill
Author(s):  
Luke Cielonko ◽  
Tyler Hamby ◽  
John S. Dallas ◽  
Luke Hamilton ◽  
Don P. Wilson

AbstractBackground:Early diagnosis and expeditious treatment of newborns with congenital hypothyroidism (CH) is necessary to avoid mental retardation.Methods:A survey of 44 practitioners in the southern US was conducted to better understand common practices regarding neonatal CH and the findings were compared with current guidelines in the US and Europe.Results:Responses indicated some consensus that 10–15 μg of thyroid hormone/kg/day was the appropriate dosage. However, despite guidelines advocating their use, practitioners reported that they did not commonly use imaging or laboratory tests, though experienced providers apparently used them more often.Conclusions:Together, these results show moderate adherence to published guidelines for treating and diagnosing CH. Further research is needed to determine why providers deviate from these guidelines and to generalize these results to other populations.


2021 ◽  
pp. 100-100
Author(s):  
Biljana Vuletic ◽  
Aleksandar Kocovic ◽  
Marija Mladenovic ◽  
Zoran Lekovic ◽  
Vladimir Radlovic ◽  
...  

Gluten-related disorders are a heterogeneous group of clinical entities caused by intolerance of wheat, rye, and barley flour components. They occur in 3-5% of genetically predisposed persons and based on pathogenic and clinical features are classified into celiac disease, non-celiac gluten sensitivity, and wheat allergy. There are also specific entities such as dermatitis herpetiformis or gluten ataxia, which can occur either within the celiac disease or independently. This article based on the current knowledge shows the basic details of the pathogenesis, clinical expression, diagnosis, and treatment of these disorders.


2021 ◽  
Vol 17 (16) ◽  
pp. 92-100
Author(s):  
S.V. Bykova ◽  
◽  
E.A. Sabelnikova ◽  
E.I. Zadiran ◽  
A.I. Parfenov ◽  
...  

The aim is to assess the awareness of general practitioners, gastroenterologists and other specialists on the methods of celiac disease diagnosis and treatment. Materials and methods. A single-stage continuous cross-sectional study of celiac disease awareness among general practitioners, gastroenterologists and other specialists was conducted. The level of doctors’ awareness was determined by the anonymous voluntary questionnaire using the questionnaire of 23 items developed on the basis of the Department of Non-Inflammatory Bowel Pathology (supplement). According to the answers to the questionnaire items, the knowledge of doctors in the field of diagnosis, therapy, and tactics of managing patients with celiac disease was evaluated. The study involved 197 doctors of medical organizations in Moscow and the Moscow Region. Statistical processing was performed with the use of Microsoft Excel 2016 software (Microsoft, USA) and the use of descriptive statistics methods. The data is presented in the form of absolute numbers and their fractions. Results. The survey revealed gaps in the doctors’ knowledge on the methods of celiac disease diagnosis and clinical manifestations,the definition of risk groups of patients to be examined to exclude celiac disease, the criteria for prescribing the gluten-free diet, as well as some social aspects. These studies indicate the lack of understanding of the methods of correct diagnosis and the need to improve the knowledge of doctors, the introduction of educational programs, schools for doctors and patients. Conclusion. It is necessary to improve the skills of doctors in celiac disease diagnosis and treatment in order to improve the screening and early diagnosis of celiac disease and related complications


JPRAS Open ◽  
2020 ◽  
Vol 26 ◽  
pp. 76-79
Author(s):  
Jessica Garner ◽  
Katia Sindali ◽  
Professor Barry W.E.M. Powell

2019 ◽  
Vol 69 (9) ◽  
pp. 1605-1612 ◽  
Author(s):  
Raphaël Lecomte ◽  
Nahéma Issa ◽  
Benjamin Gaborit ◽  
Paul Le Turnier ◽  
Colin Deschanvres ◽  
...  

Abstract Background In the management of infective endocarditis (IE), the presence of extracardiac complications has an influence on both diagnosis and treatment. Current guidelines suggest that systematic thoracoabdominal-pelvic computed tomography (TAP-CT) may be helpful. Our objective was to describe how systematic TAP-CT affects the diagnosis and the management of IE. Methods In this multicenter cohort study, between January 2013 and July 2016 we included consecutive patients who had definite or possible IE according to the Duke modified criteria, validated by endocarditis teams. We analyzed whether the Duke classification and therapeutic management were modified regarding the presence or the absence of IE-related lesion on CT and investigated the tolerance of this examination. Results Of the 522 patients included in this study, 217 (41.6%) had 1 or more IE-related lesions. On the basis of CT results in asymptomatic patients, diagnostic classification was upgraded from possible endocarditis to definite endocarditis for only 4 cases (0.8%). The presence of IE-related lesions on CT did not modify the duration of antibiotic treatment (P = .55), nor the decision of surgical treatment (P = .39). Specific treatment of the lesion was necessary in 42 patients (8.0%), but only 9 of these lesions (1.9%) were asymptomatic and diagnosed only on the TAP-CT. Acute kidney injury (AKI) within 5 days of CT was observed in 78 patients (14.9%). Conclusions The TAP-CT findings slightly affected diagnosis and treatment of IE in a very small proportion of asymptomatic patients. Furthermore, contrast media should be used with caution because of the high risk of AKI.


1950 ◽  
Vol 7 (4) ◽  
pp. 239-250 ◽  
Author(s):  
Sidney V. Haas ◽  
Merrill P. Haas

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