Influence of Pancreatic Duct Occlusion on Islet Hormones in Peripheral and Portal Plasma and in the Pancreas of the Mini-Pig

1985 ◽  
Vol 17 (1) ◽  
pp. 17-24 ◽  
Author(s):  
P.O. Schwille ◽  
W. Engelhardt ◽  
H. Volkholz ◽  
C. Gebhardt ◽  
H. ZimgïbV ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Duct Occlusion ◽  
Islet Hormones ◽  
Duct Occlusion ◽  
Portal Plasma

scholarly journals Postoperative Outcomes Analysis After Pancreatic Duct Occlusion: A Safe Option to Treat the Pancreatic Stump After Pancreaticoduodenectomy in Low-Volume Centers

2021 ◽  
Vol 8 ◽  
Author(s):  
Antonio Giuliani ◽  
Pasquale Avella ◽  
Anna Lucia Segreto ◽  
Maria Lucia Izzo ◽  
Antonio Buondonno ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Postoperative Outcomes ◽  
Cyanoacrylate Glue ◽  
Pancreatic Anastomosis ◽  
Pancreatic Stump ◽  
Pancreatic Duct Occlusion ◽  
Duct Occlusion ◽  
Whipple’S Procedure ◽  
The Mean

Background: Surgical resection is the only possible choice of treatment in several pancreatic disorders that included periampullar neoplasms. The development of a postoperative pancreatic fistula (POPF) is the main complication. Despite three different surgical strategies that have been proposed–pancreatojejunostomy (PJ), pancreatogastrostomy (PG), and pancreatic duct occlusion (DO)–none of them has been clearly validated to be superior. The aim of this study was to analyse the postoperative outcomes after DO.Methods: We retrospectively reviewed 56 consecutive patients who underwent Whipple's procedure from January 2007 to December 2014 in a tertiary Hepatobiliary Surgery and Liver Transplant Unit. After pancreatic resection in open surgery, we performed DO of the Wirsung duct with Cyanoacrylate glue independently from the stump characteristics. The mean follow-up was 24.5 months.Results: In total, 29 (60.4%) were men and 19 were (39.6%) women with a mean age of 62.79 (SD ± 10.02) years. Surgical indications were in 95% of cases malignant diseases. The incidence of POPF after DO was 31 (64.5%): 10 (20.8%) patients had a Grade A fistula, 18 (37.5%) Grade B fistula, and 3 (6.2%) Grade C fistula. No statistical differences were demonstrated in the development of POPF according to pancreatic duct diameter groups (p = 0.2145). Nevertheless, the POPF rate was significantly higher in the soft pancreatic group (p = 0.0164). The mean operative time was 358.12 min (SD ± 77.03, range: 221–480 min). Hospital stay was significantly longer in patients who developed POPF (p < 0.001). According to the Clavien-Dindo (CD) classification, seven of 48 (14.58%) patients were classified as CD III–IV. At the last follow-up, 27 of the 31 (87%) patients were alive.Conclusions: Duct occlusion could be proposed as a safe alternative to pancreatic anastomosis especially in low-/medium-volume centers in selected cases at higher risk of clinically relevant POPF.

Intestinal Disaccharidase Activity Following Pancreatic Duct Occlusion in the Rat

Pancreas ◽  
1987 ◽  
Vol 2 (3) ◽  
pp. 295-302 ◽  
Author(s):  
M. Hauer-Jensen ◽  
K. Christensen ◽  
H. D. Wilson ◽  
H. P. Schedl
Keyword(s):  
Pancreatic Duct ◽  
Disaccharidase Activity ◽  
Pancreatic Duct Occlusion ◽  
Duct Occlusion

Role of Cholecystokinin-A (CCK-A) Receptor in Pancreatic Regeneration After Pancreatic Duct Occlusion

Pancreas ◽  
1998 ◽  
Vol 16 (2) ◽  
pp. 114-123 ◽  
Author(s):  
Kyoko Miyasaka ◽  
Minoru Ohta ◽  
Kayoko Tateishi ◽  
Atsuo Jimi ◽  
Akihiro Funakoshi
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Regeneration ◽  
Pancreatic Duct Occlusion ◽  
Duct Occlusion

Temporary Pancreatic Duct Occlusion by Ethibloc: Cause of Microcirculatory Shutdown, Acute Inflammation, and Pancreas Necrosis

2001 ◽  
Vol 25 (4) ◽  
pp. 432-437 ◽  
Author(s):  
Thorsten Plusczyk ◽  
Simone Westermann ◽  
Björn Bersal ◽  
Michael Menger ◽  
Gernot Feifel
Keyword(s):  
Pancreatic Duct ◽  
Acute Inflammation ◽  
Pancreatic Duct Occlusion ◽  
Duct Occlusion ◽  
Pancreas Necrosis

Long-term pancreatic duct occlusion impairs the entero-insular axis in the dog—Failure of plasma VIP to respond as “incretin”

Peptides ◽  
1984 ◽  
Vol 5 (2) ◽  
pp. 445-450 ◽  
Author(s):  
P.O. Schwille ◽  
W. Engelhardt ◽  
E. Gumbert ◽  
C. Gebhardt ◽  
F.P. Gall
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Duct Occlusion ◽  
Duct Occlusion
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