Home Non-Invasive Mechanical Ventilation and Long-Term Oxygen Therapy in Stable Hypercapnic Chronic Obstructive Pulmonary Disease Patients: Comparison of Costs

Respiration ◽  
2008 ◽  
Vol 77 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Enrico M. Clini ◽  
Giovanna Magni ◽  
Ernesto Crisafulli ◽  
Stefano Viaggi ◽  
Nicolino Ambrosino
ESC CardioMed ◽  
2018 ◽  
pp. 1047-1050
Author(s):  
Anita K. Simonds

There is a well-established evidence base for prescribing long-term oxygen therapy in chronic obstructive pulmonary disease, and this has been extrapolated to management of hypoxaemia in other conditions such as interstitial lung disease and chronic pulmonary hypertension. Non-invasive ventilation reduces mortality in chronic stable hypercapnic patients with chronic obstructive pulmonary disease and those who remain persistently hypercapnic following an acute infective exacerbation. In patients with some neuromuscular disorders, non-invasive ventilation may increase survival and quality of life significantly. Few cardiovascular endpoints have been monitored systematically in these populations.


2018 ◽  
Vol 16 ◽  
pp. 147997231876772 ◽  
Author(s):  
Amélie Gauthier ◽  
Sarah Bernard ◽  
Emmanuelle Bernard ◽  
Serge Simard ◽  
François Maltais ◽  
...  

Long-term oxygen therapy (LTOT) has beneficial effects on survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia at rest. Two landmark trials suggested that these benefits depend on the time of exposure to oxygen. Patients are usually prescribed LTOT for at least 15–18 hours/day. The primary objective of this study was to determine the average daily exposure to supplemental oxygen in patients with severely hypoxemic COPD who were newly prescribed LTOT and the proportion of patients who were adherent to their prescription. The secondary objective was to identify predictors of compliance to LTOT. We performed a retrospective observational study of patients newly registered in a regional home oxygen program in Quebec, Canada, between July 1, 2013, and December 31, 2014. Daily exposure to oxygen was objectively measured from the concentrator’s counter clock. From 196 patients registered in the program during the study period, 115 contributed to the analysis. Most patients ( n = 84; 73%) were prescribed oxygen for ≥18 hours/day. Overall, the 115 patients were exposed to home oxygen for 17.8 hours/day; 60% of the patients were compliant according to our definition. Increasing age and ambulatory oxygen utilization predicted adherence to oxygen therapy. Adherence to home oxygen therapy is suboptimal. Behavioral and psychological interventions to improve compliance to LTOT should be investigated.


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