Relationship of Plasma Growth Hormone to Slow-Wave Sleep in African Sleeping Sickness

1996 ◽  
Vol 63 (4) ◽  
pp. 393-396 ◽  
Author(s):  
Manny W. Radomski ◽  
Alain Buguet ◽  
Félix Doua ◽  
Pascal Bogui ◽  
Philippe Tapie
1975 ◽  
Vol 40 (5) ◽  
pp. 812-815 ◽  
Author(s):  
U. BECK ◽  
V. BŘEZINOVÁ ◽  
W. M. HUNTER ◽  
IAN OSWALD

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S60-S61
Author(s):  
J. BORN ◽  
R. PIETROWSKY ◽  
P. PAUSCHINGER ◽  
H. L. FEHM

2012 ◽  
Vol 13 (1) ◽  
pp. 96-101 ◽  
Author(s):  
Nea Kalleinen ◽  
Arho Virkki ◽  
Olli Polo ◽  
Sari-Leena Himanen ◽  
Kerttu Irjala ◽  
...  

1993 ◽  
Vol 9 (2-3) ◽  
pp. 154
Author(s):  
K.L. Benson ◽  
K.O. Lim ◽  
J. Lauriello ◽  
V.P. Zarcone ◽  
A. Pfefferbaum

1986 ◽  
Vol 20 (11) ◽  
pp. 1188-1188
Author(s):  
J Argente ◽  
D Evain Brion ◽  
P Garnier ◽  
M Hernandez ◽  
M Donnadieu ◽  
...  

1998 ◽  
Vol 274 (5) ◽  
pp. E779-E784 ◽  
Author(s):  
Rodrigo Moreno-Reyes ◽  
Myriam Kerkhofs ◽  
Mireille L’Hermite-Balériaux ◽  
Michael O. Thorner ◽  
Eve Van Cauter ◽  
...  

A complex interrelationship exists between sleep and somatotropic activity. In humans, intravenous injections of growth hormone-releasing hormone (GHRH) given during sleep consistently stimulate slow-wave (SW) sleep, particularly when given in the latter part of the night. In the present study, the possible somnogenic effects induced under similar conditions by GH-releasing peptide (GHRP) were investigated in seven young healthy men. Bolus intravenous injections of GHRP-2 (1 μg/kg body wt) or saline, in randomized order, were given after 60 s of the third rapid-eye-movement period. All GHRP injections were immediately followed by transient prolactin elevations and by GH pulses of a magnitude within or around the upper limit of the physiological range. Except for a nonsignificant tendency to increased amounts of wakefulness during the 1st h after the injection, no effects of GHRP-2 administration on sleep were detected. There was in particular no enhancement of SW sleep. Thus, in contrast to GHRH, late-night single injections of GHRP-2 at a dosage resulting in similar GH elevations have no stimulatory effects on SW sleep. The present data provide evidence against the involvement of the GHRP axis in human SW sleep regulation.


1999 ◽  
Vol 41 (2) ◽  
pp. 192-194 ◽  
Author(s):  
Kuniaki Iyoda ◽  
Hitoshi Tobiume ◽  
Susumu Kanzaki ◽  
Syouko Takano2 And Yoshiki Seino

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