Growth Hormone Secretion Is Differently Affected in Genetically Obese Male and Female Rats

1993 ◽  
Vol 57 (5) ◽  
pp. 928-934 ◽  
Author(s):  
Daniela Cocchi ◽  
Marco Parenti ◽  
Lorena Cattaneo ◽  
V. De Gennaro Colonna ◽  
Andrea Zocchetti ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Female Rats ◽  
Male And Female ◽  
Male And Female Rats ◽  
Obese Male

PITUITARY HORMONE SECRETION IN THE GENETICALLY MALE RAT PSEUDOHERMAPHRODITE

1975 ◽  
Vol 64 (2) ◽  
pp. 249-255 ◽  
Author(s):  
A. S. GOLDMAN ◽  
A. W. ROOT ◽  
G. DUCKETT ◽  
B. H. SHAPIRO
Keyword(s):  
Growth Hormone ◽  
Follicle Stimulating Hormone ◽  
Hormone Secretion ◽  
Female Rats ◽  
Male Rat ◽  
Normal Male ◽  
Pituitary Hormone ◽  
Male And Female ◽  
Male And Female Rats ◽  
Serum Lh

SUMMARY Pituitary content or concentration of follicle-stimulating hormone (FSH), prolactin and growth hormone in the genetically androgen insensitive male rat pseudohermaphrodite is intermediate between normal male and female rats, while pituitary luteinizing hormone (LH) concentration and serum FSH levels are the same as in the normal male. The concentration of serum LH, prolactin and growth hormone indicates no sexual dimorphism. Although the pseudohermaphrodite is genetically male with a female phenotype, our results suggest some degree of masculinization of the hypothalamicpituitary system.

Significance of the Secretory Pattern of Growth Hormone

Physiology ◽  
1986 ◽  
Vol 1 (2) ◽  
pp. 44-47
Author(s):  
OGP Isakkson ◽  
J-O Jansson ◽  
RG Clark ◽  
I Robinson
Keyword(s):  
Growth Hormone ◽  
Plasma Concentration ◽  
High Amplitude ◽  
Female Rats ◽  
Healthy Children ◽  
Male And Female ◽  
Male And Female Rats ◽  
Low Concentrations ◽  
Lower Amplitude ◽  
Secretory Pattern

The plasma concentration of growth hormone fluctuates widely with pronounced peaks at intervals of a few hours and troughs of nearly vanishingly low concentrations in between. The pattern of secretion varies, and different patterns affect growth differently. Tall children usually have frequent growth hormone peaks of a high amplitude, whereas short, healthy children usually have fewer peaks of a lower amplitude. Male and female rats have different patterns, and a "masculine" pattern promotes growth more than a "feminine" pattern. If the same amount of growth hormone is administered in several pulses rather than continuously, the effect on growth is much greater.

Regulation of luteinizing hormone secretion in prepubertal male and female rats

Life Sciences ◽  
1982 ◽  
Vol 31 (20-21) ◽  
pp. 2167-2170 ◽  
Author(s):  
Rüdiger Schulz ◽  
Annemarie Wilhelm ◽  
Karl Martin Pirke ◽  
Albert Herz
Keyword(s):  
Luteinizing Hormone ◽  
Hormone Secretion ◽  
Female Rats ◽  
Luteinizing Hormone Secretion ◽  
Male And Female ◽  
Male And Female Rats

Increased hypothalamic somatostatin mRNA following dexamethasone administration in rats

1992 ◽  
Vol 127 (5) ◽  
pp. 416-419 ◽  
Author(s):  
Koji Nakagawa ◽  
Tatsuya Ishizuka ◽  
Chikara Shimizu ◽  
Yoshito Ito ◽  
Ichiji Wakabayashi
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Female Rats ◽  
Mrna Levels ◽  
Plasma Growth Hormone ◽  
Hormone Production ◽  
Blot Technique ◽  
Series Of Experiments

There is increasing evidence to suggest that supraphysiological doses of glucocorticoids suppress growth hormone secretion in vivo by augmenting somatostatin release from the hypothalamus; previously, we reported an increase in hypothalamic somatostatin content in dexamethasone-treated rats. To further examine whether the production of somatostatin really is augmented, hypothalamic somatostatin mRNA levels were determined by the Northern blot technique in female rats receiving 330 μg of dexamethasone daily for three days. In two series of experiments, hypothalamic somatostatin mRNA levels in dexamethasone-treated rats were significantly (p<0.05) increased to 133±19 (mean±sd)% and 153±38% of the controls. In the dexamethasone-treated rats, plasma growth hormone levels were markedly suppressed compared with those of the controls. These results further support the hypothesis that pharmacological doses of glucocorticoids increase the production and release of somatostatin from the hypothalamus and thus inhibit growth hormone secretion, overriding the direct stimulatory effect of glucocorticoids on growth hormone production at the pituitary level.

Microinjection of Dihydrotestosterone into the Medial Preoptic Area Produces Male-Like Pattern of Growth Hormone Secretion in Ovariectomized Female Rats

2002 ◽  
Vol 75 (6) ◽  
pp. 384-391 ◽  
Author(s):  
Reiko Tokita ◽  
Yoko Kasagi ◽  
Tomoko Nakata ◽  
Kensaku Sakae ◽  
Toshihiro Imaki ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Preoptic Area ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Medial Preoptic Area ◽  
Female Rats
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