Growth Hormone Pulsatility and the Endocrine Milieu during Sexual Maturation in Male and Female Rats

1992 ◽  
Vol 56 (5) ◽  
pp. 619-628 ◽  
Author(s):  
Steven M. Gabriel ◽  
Jaime R. Roncancio ◽  
Nancy S. Ruiz
Keyword(s):  
Growth Hormone ◽  
Sexual Maturation ◽  
Female Rats ◽  
Male And Female ◽  
Male And Female Rats

scholarly journals The influence of psychological stress in early life on sexual maturation and sexual behavior in male and female rats

2020 ◽  
Vol 19 (2) ◽  
pp. 135-141
Author(s):  
Kiyohito Yano ◽  
Toshiya Matsuzaki ◽  
Takeshi Iwasa ◽  
Yiliyasi Mayila ◽  
Rie Yanagihara ◽  
...  
Keyword(s):  
Sexual Behavior ◽  
Psychological Stress ◽  
Sexual Maturation ◽  
Early Life ◽  
Female Rats ◽  
Male And Female ◽  
Male And Female Rats

Significance of the Secretory Pattern of Growth Hormone

Physiology ◽  
1986 ◽  
Vol 1 (2) ◽  
pp. 44-47
Author(s):  
OGP Isakkson ◽  
J-O Jansson ◽  
RG Clark ◽  
I Robinson
Keyword(s):  
Growth Hormone ◽  
Plasma Concentration ◽  
High Amplitude ◽  
Female Rats ◽  
Healthy Children ◽  
Male And Female ◽  
Male And Female Rats ◽  
Low Concentrations ◽  
Lower Amplitude ◽  
Secretory Pattern

The plasma concentration of growth hormone fluctuates widely with pronounced peaks at intervals of a few hours and troughs of nearly vanishingly low concentrations in between. The pattern of secretion varies, and different patterns affect growth differently. Tall children usually have frequent growth hormone peaks of a high amplitude, whereas short, healthy children usually have fewer peaks of a lower amplitude. Male and female rats have different patterns, and a "masculine" pattern promotes growth more than a "feminine" pattern. If the same amount of growth hormone is administered in several pulses rather than continuously, the effect on growth is much greater.

Growth hormone responses to multiple injections of a fragment of human growth hormone-releasing factor in conscious male and female rats

1985 ◽  
Vol 106 (3) ◽  
pp. 281-289 ◽  
Author(s):  
R. G. Clark ◽  
I. C. A. F. Robinson
Keyword(s):  
Growth Hormone ◽  
Human Growth ◽  
Female Rats ◽  
Male Rats ◽  
Normal Male ◽  
Male And Female ◽  
Gh Secretion ◽  
Male And Female Rats ◽  
Hormone Responses ◽  
Males And Females

ABSTRACT The GH responses to single i.v. injections of GH-releasing factor (GRF) in conscious male rats are highly variable. Although normal male rats show a pulsatile secretory pattern of GH with pulses occurring at intervals of 3–3·5 h, the peaks occur at different times in individual animals. We have compared the GH responses of young conscious male and female rats to multiple i.v. injections of 1 μg human (h) GRF1-29NH2. The peak GH responses occurred 3–5 min after hGRF1-29NH2 injection and were lower in female than in male rats. Both males and females responded uniformly to hGRF1-29NH2 injections given 180 min apart and the GH responses became entrained with no endogenous GH pulsing. Female rats produced consistent GH peaks in response to hGRF1-29NH2 injections at 90-min intervals, whereas male rats responded only to alternate injections, so that GH peaks occurred only every 180 min despite giving GRF every 90 min. When the frequency of hGRF1-29NH2 administration was increased to once every 40 min female rats again responded consistently to each injection. Male rats responded intermittently, being able to respond to two injections 40 min apart, after which they became refractory to hGRF1-29NH2. This cycle of varying sensitivity to GRF in male rats probably underlies their 3-hourly endogenous GH secretory rhythm. Female rats can respond uniformly to repeated GRF injections, consistent with their more continuous pattern of endogenous GH secretion. Introducing a pulse of 10 μg rat GH into a series of hGRF1-29NH2 injections did not induce refractoriness to hGRF1-29NH2, suggesting that GH does not itself desensitize the pituitary to GRF. Whether the different patterns of GH secretion in males and females result from different patterns of GRF and/or somatostatin secretion remains to be determined. J. Endocr. (1985) 106, 281–289

Changes in the growth hormone axis due to exercise training in male and female rats: secretory and molecular responses.

Endocrinology ◽  
1995 ◽  
Vol 136 (6) ◽  
pp. 2664-2670 ◽  
Author(s):  
J A Butkus ◽  
R S Brogan ◽  
A Giustina ◽  
G Kastello ◽  
M Sothmann ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Exercise Training ◽  
Female Rats ◽  
Molecular Responses ◽  
Male And Female ◽  
Male And Female Rats

PHYSIOLOGIC SECRETION OF GROWTH HORMONE AND PROLACTIN IN MALE AND FEMALE RATS

1977 ◽  
Vol 6 (s1) ◽  
pp. 19-28 ◽  
Author(s):  
LEON C. TERRY ◽  
ADAH SAUNDERS ◽  
JUDY AUDET ◽  
JOHN O. WILLOUGHBY ◽  
PAUL BRAZEAU ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Female Rats ◽  
Male And Female ◽  
Male And Female Rats

Orphanin FQ stimulates prolactin and growth hormone release in male and female rats

1998 ◽  
Vol 807 (1-2) ◽  
pp. 228-233 ◽  
Author(s):  
Winnifred Bryant ◽  
James Janik ◽  
Michael Baumann ◽  
Phyllis Callahan
Keyword(s):  
Growth Hormone ◽  
Female Rats ◽  
Hormone Release ◽  
Growth Hormone Release ◽  
Orphanin Fq ◽  
Male And Female ◽  
Male And Female Rats
Sign in / Sign up

Export Citation Format

Share Document