Postovariectomy Decline in the in vitro Release of LH-Releasing Hormone Is Not Manifested in Aging Female Rats

1990 ◽  
Vol 52 (5) ◽  
pp. 497-502 ◽  
Author(s):  
Ayalla Barnea ◽  
Kala R. Bhasker
Keyword(s):  
In Vitro Release ◽  
Female Rats ◽  
Releasing Hormone ◽  
Lh Releasing Hormone ◽  
Vitro Release

In vitro Release of LHRH from the Hypothalamus of Female Rats during Prepubertal Development

1982 ◽  
Vol 35 (1) ◽  
pp. 8-12 ◽  
Author(s):  
P.G.A. Hompes ◽  
I. Vermes ◽  
F.J.H. Tilders ◽  
J. Schoemaker
Keyword(s):  
In Vitro Release ◽  
Female Rats ◽  
Vitro Release

Pituitary receptors for LH-releasing hormone (LHRH) and responsiveness to LHRH in adult female rats after neonatal monosodium l-glutamate treatment

1985 ◽  
Vol 107 (1) ◽  
pp. 9-13 ◽  
Author(s):  
S. E. Inkster ◽  
R. N. Clayton ◽  
S. A. Whitehead
Keyword(s):  
Adult Female ◽  
Female Rats ◽  
Serum Prolactin ◽  
Female Rat ◽  
Releasing Hormone ◽  
Old Rats ◽  
Lh Releasing Hormone ◽  
Ovarian Cyclicity ◽  
Pituitary Receptors

ABSTRACT The effects of neonatal monosodium l-glutamate (MSG) treatment on pituitary responsiveness to LH-releasing hormone (LHRH) and on pituitary LHRH receptors have been investigated in the intact adult female rat. Three- to four-month-old rats treated with MSG (4 mg/g body wt) on days 2, 4, 6, 8 and 10 after birth had significantly reduced ovarian and pituitary weights, showed an absence or disruption of ovarian cyclicity after puberty, and had significantly higher concentrations of serum prolactin despite normal levels of LH. In-vitro pituitary LH responses to LHRH were in the normal range for one group of treated animals whilst in a second group the LH responses were markedly enhanced. In contrast, the total number of pituitary LHRH receptors were significantly reduced in all MSG-treated animals showing that the increased pituitary responsiveness of MSG-treated animals is not attributable to an increase in pituitary LHRH receptors. J. Endocr. (1985) 107, 9–13

GONADOTROPHIN RELEASE IN VITRO, IN THE PRESENCE AND ABSENCE OF LUTEINIZING HORMONE RELEASING HORMONE, BY PITUITARY GLANDS FROM OVARIECTOMIZED AND SHAM-OPERATED IMMATURE FEMALE RATS OF VARIOUS AGES

1981 ◽  
Vol 88 (3) ◽  
pp. 375-379
Author(s):  
J. DULLAART
Keyword(s):  
Female Rats ◽  
Ovariectomized Rats ◽  
Immature Female ◽  
Releasing Hormone ◽  
Incubation Experiments ◽  
Immature Rats ◽  
Pituitary Glands ◽  
Lh Releasing Hormone

Hemipituitary glands of immature female rats, aged 10, 15, 20, 25, 30 and 35 days and either ovariectomized or sham-operated 5 days earlier, were incubated for 2 h in vitro with or without LH releasing hormone. Concentrations of LH and FSH were determined at the end of the incubations in the incubation media and in the hemipituitary glands, and also in the sera collected at the beginning of the incubation experiments. Results showed that in many instances gonadotrophin release was higher after incubation of glands of ovariectomized rats than with glands of control animals. However, these effects of ovariectomy were much smaller than those observed in vivo and were generally absent in rats of less than 20 days of age. It was concluded that ovariectomy may change the secretory characteristics of the gonadotrophic cells of immature rats but that such changes were largely restricted to immature rats older than 20 days.

Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain

Peptides ◽  
1987 ◽  
Vol 8 (2) ◽  
pp. 291-298 ◽  
Author(s):  
Milagros Mendez ◽  
Patricia Joseph-Bravo ◽  
Miguel Cisneros ◽  
Miguel Angel Vargas ◽  
Jean-Louis Charli
Keyword(s):  
Rat Brain ◽  
Regional Distribution ◽  
In Vitro Release ◽  
Thyrotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Vitro Release
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