Antisera to Vasoactive Intestinal Polypeptide Inhibit Basal Prolactin Release from Dispersed Anterior Pituitary Cells

1986 ◽  
Vol 43 (6) ◽  
pp. 641-645 ◽  
Author(s):  
Thad C. Hagen ◽  
Mohammed A. Arnaout ◽  
Wendy J. Scherzer ◽  
Donald R. Martinson ◽  
Thomas L. Garthwaite
1991 ◽  
Vol 12 (2) ◽  
pp. 071-075 ◽  
Author(s):  
FERNANDO SANCHEZ ◽  
JOSE I. LARA ◽  
LUCINDA CACICEDO ◽  
FRANCO SANCHEZ-FRANCO ◽  
JOSE CARRETERO ◽  
...  

1988 ◽  
Vol 118 (2) ◽  
pp. 179-NP ◽  
Author(s):  
T. Noguchi ◽  
T. Sugisaki ◽  
T. Kanamatsu ◽  
I. Satoh ◽  
N. Nishikawa

ABSTRACT The prolactin-producing cells of the bovine anterior pituitary were found to contain a vasoactive intestinal polypeptide (VIP) immunoreactive substance, thus suggesting a role for VIP in the regulation of prolactin release. The pituitaries of the dw and lit strains of mutant mice, congenitally deficient in prolactin-producing cells, and hyt mice, which were found to have reduced numbers of prolactin-producing cells, showed a markedly reduced VIP immunoreactivity. Hypothalamic VIP immunoreactivity, however, was found to be unchanged in the three strains of mutant mice, indicating that the high concentration of VIP in the hypothalamus does not derive from the adenohypophysis through retrograde flow. The deficiency in the mutant mice seems to be due to the lack of prolactin target cells in the pituitary. J. Endocr. (1988) 118, 179–185


Life Sciences ◽  
1983 ◽  
Vol 32 (11) ◽  
pp. 1263-1269 ◽  
Author(s):  
Norio Matsushita ◽  
Yuzuru Kato ◽  
Akira Shimatsu ◽  
Hideki Katakami ◽  
Noboru Yanaihara ◽  
...  

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