Hyperbaric Oxygen Treatment Restores Sudden Hearing Loss in a Patient with Fabry Disease

ORL ◽  
2008 ◽  
Vol 70 (3) ◽  
pp. 210-213 ◽  
Author(s):  
Markus C. Frantz ◽  
Bertram F. Pontz ◽  
Wolfgang Arnold
Keyword(s):  
Hearing Loss ◽  
Fabry Disease ◽  
Hyperbaric Oxygen ◽  
Sudden Hearing Loss ◽  
Hyperbaric Oxygen Treatment ◽  
Oxygen Treatment

scholarly journals Hyperbaric Oxygen Treatment Ameliorates Hearing Loss and Auditory Cortex Injury in Noise Exposed Mice by Repressing Local Ceramide Accumulation

2019 ◽  
Vol 20 (19) ◽  
pp. 4675 ◽  
Author(s):  
Su ◽  
Guo ◽  
Cheng ◽  
Zhang ◽  
Xie ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Auditory Cortex ◽  
Hyperbaric Oxygen ◽  
Noise Exposure ◽  
Neuronal Degeneration ◽  
Broad Band ◽  
Tunel Staining ◽  
Hyperbaric Oxygen Treatment ◽  
Oxygen Treatment ◽  
Brainstem Response

Noise-induced hearing loss (NIHL) relates closely to auditory cortex (AC) injury, so countermeasures aiming at the AC recovery would be of benefit. In this work, the effect of hyperbaric oxygen treatment on NIHL was elucidated, which was imposed on mice before (HBOP), during (HBOD) or after (HBOA) noise exposure. Morphology of neurons was assayed by hematoxylin-eosin or Nissl staining. Ceramide (Cer) level was measured through immunohistochemistry analysis. Apoptotic neurons were counted using transferase-mediated dUTP nick end labeling (TUNEL) staining. We demonstrated that the intense, broad band noise raised the threshold of auditory brainstem response, evoked neuronal degeneration or apoptosis and triggered the Cer accumulation in AC, all of which were restored significantly by HBOP, but not HBOD or HBOA. Cer over-generation reversed the advantages of HBOP significantly, while its curtailment recapitulated the effect. Next, noise exposure raised the superoxide or malondialdehyde (MDA) production which was blocked by HBOP or Cer repression. Oxidative control not only attenuated the hearing loss or neurodegeneration but, in turn, reduced the Cer formation significantly. In summary, mutual regulation between Cer and oxidative stress underlies the HBOP’s curative effect on hearing loss and neuronal damage in noise-exposed mice.

Hyperoxic myopia: a case series of four divers

2020 ◽  
pp. 261-265
Author(s):  
Jonathan W. Brügger ◽  
Glenn A. Rauscher ◽  
John P. Florian ◽  
Keyword(s):  
Hyperbaric Oxygen ◽  
Prolonged Exposure ◽  
Case Series ◽  
Oxygen Toxicity ◽  
Hyperbaric Oxygen Treatment ◽  
Subjective Data ◽  
Residual Symptoms ◽  
Oxygen Treatment ◽  
Blurry Vision ◽  
Record Review

Hyperoxic myopia is a phenomenon reported in individuals who have prolonged exposure to an increased partial pressure of oxygen (PO2) and subsequently have a myopic (nearsighted) change in their vision. To date, there are numerous accounts of hyperoxic myopia in dry hyperbaric oxygen treatment patients; however, there have been only three confirmed cases reported in wet divers. This case series adds four confirmed cases of hyperoxic myopia in wet divers using 1.35 atmospheres (ATM) PO2 at the Navy Experimental Diving Unit (NEDU). The four divers involved were the first author’s patients at NEDU. Conditions for two divers were confirmed via record review, whereas the other two divers were diagnosed by the first author. All subjects were interviewed to correlate subjective data with objective findings. Each subject completed five consecutive six-hour hyperoxic (PO2 of 1.35 ATM) dives with 18-hour surface intervals. Each individual was within the U. S. Navy Dive Manual’s standards for general health. Visual acuity was measured prior to diving. Within three to four days after diving, the individuals reported blurry vision with an associated myopic refraction shift. Each diver had spontaneous resolution of his myopia over the next two to three weeks, with no significant residual symptoms. The divers in this case series were exposed to an increased PO2 (1.35 ATM for 30 hours over five days), a lesser exposure than that in other reports of hyperoxic myopia in wet divers diagnosed with hyperoxic myopia (1.3-1.6 ATM for 45-85 hours in 12-18 days). Furthermore, this pulse of exposure was more concentrated than typically seen with traditional hyperbaric oxygen therapy. Hyperoxic myopia continues to be a risk for those conducting intensive diving with a PO2 between 1.3-1.6 ATM. Additional investigation is warranted to better define risk factors and PO2 limits regarding ocular oxygen toxicity.

Review on hyperbaric oxygen treatment in femoral head necrosis

2017 ◽  
Vol 44 (6) ◽  
pp. 497-508 ◽  
Author(s):  
Enrico Camporesi ◽  
◽  
Giuliano Vezzani ◽  
Vincenzo Zanon ◽  
Daniele Manelli ◽  
...  
Keyword(s):  
Femoral Head ◽  
Hyperbaric Oxygen ◽  
Femoral Head Necrosis ◽  
Hyperbaric Oxygen Treatment ◽  
Oxygen Treatment

The Effect of Hyperbaric Oxygen Treatment on the Healing of Burn Wounds in Nicotinized and Nonnicotinized Rats

2013 ◽  
Vol 34 (4) ◽  
pp. e237-e243 ◽  
Author(s):  
Caferi Tayyar Selçuk ◽  
Burhan Özalp ◽  
Mustafa Durgun ◽  
Alicem Tekin ◽  
Mehmet Fatih Akkoç ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Treatment ◽  
Burn Wounds ◽  
Oxygen Treatment

Effect of hyperbaric oxygen treatment on immunological parameters in multiple sclerosis

1989 ◽  
Vol 79 (4) ◽  
pp. 306-310 ◽  
Author(s):  
H. Nyland ◽  
A. Naess ◽  
S. Eidsvik ◽  
J. Glette ◽  
R. Matre ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Treatment ◽  
Immunological Parameters ◽  
Oxygen Treatment
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