Responsiveness of Immature versus Adult Male Rat Hypothalami to Dibutyryl Cyclic AMP- and Forskolin-Induced LHRH Release in vitro

1985 ◽  
Vol 40 (6) ◽  
pp. 476-482 ◽  
Author(s):  
Daryl E. Hartter ◽  
Victor D. Ramirez
Nature ◽  
1974 ◽  
Vol 248 (5446) ◽  
pp. 343-344 ◽  
Author(s):  
NORMAN H. BELL ◽  
SHERRY QUEENER

1979 ◽  
Vol 44 (5) ◽  
pp. 1651-1656 ◽  
Author(s):  
Sixtus Hynie ◽  
Jiří Smrt

3'-Oleolyl-2,3-dihydroxypropyl-AMP, 3'-stearoyl-2,3-dihydroxypropyl-AMP, octadecyl-AMP and palmitamidoethyl-AMP inhibited in comparison with adenosine or fatty acids much stronger the lipolysis in rat epididymal fat pads in vitro stimulated by isoproterenol, theophylline and dibutyryl cyclic AMP. The inhibition of the effects of the two latter drugs suggest that the described effect is caused not only by the inhibition of the cyclic AMP production but also by the inhibition of its effect on the following steps in process of lipolysis.


2014 ◽  
Vol 76 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Erin K. Zinkhan ◽  
Brook Y. Lang ◽  
Baifeng Yu ◽  
Yan Wang ◽  
Chengshe Jiang ◽  
...  

2016 ◽  
Vol 258 ◽  
pp. S308-S309 ◽  
Author(s):  
M. Kemény ◽  
H.A. Marxfeld ◽  
R. Buesen ◽  
A. Chukwudebe ◽  
B. Van Ravenzwaay ◽  
...  
Keyword(s):  
Male Rat ◽  

1976 ◽  
Vol 71 (2) ◽  
pp. 231-238 ◽  
Author(s):  
RÉGINE PICON

SUMMARY Testosterone secretion by foetal rat testes (13½–21½ days of gestation) explanted for 3 days in a synthetic medium was measured every 24 h by radioimmunoassay. During the first day of explantation, the foetal testis produced, respectively, 1013 ± 132, 8734 ± 1118, 9179 ± 2185 and 3886 ± 309 (s.e.m.) pg/testis when explanted at 14½, 16½, 18½ and 21½ days respectively. Testosterone production by 13½-day-old testes was not detectable on the first day of culture, but appeared on subsequent days. Daily testosterone secretion increased on the 2nd and 3rd days of culture in 14½-day-old testes and decreased in older stages. These results suggest that the functional differentiation of the testis is independent of stimulatory factors like gonadotrophins. Dibutyryl cyclic AMP was found to stimulate testosterone production significantly from 14½ days of gestation onwards.


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