Influence of Brain Histaminergic System on Episodic Growth Hormone Secretion in the Rat

1982 ◽  
Vol 35 (1) ◽  
pp. 43-47 ◽  
Author(s):  
C. Netti ◽  
F. Guidobono ◽  
V.R. Olgiati ◽  
V. Sibilia ◽  
F. Pagani ◽  
...  
1982 ◽  
Vol 69 (1) ◽  
pp. 104-112 ◽  
Author(s):  
L. Cass Terry ◽  
W. R. Crowley ◽  
M. D. Johnson

1986 ◽  
Vol 7 (6) ◽  
pp. 371-377 ◽  
Author(s):  
TAKASHI MORI ◽  
SHUJI INOUE ◽  
SHIRO MINAMI ◽  
MASATO EGAWA ◽  
ICHIJI WAKABAYASHI

2002 ◽  
Vol 21 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Wallace D. Berry Jr ◽  
C. Michael Moriarty ◽  
Yuen-Sum Lau

1979 ◽  
Vol 91 (3) ◽  
pp. 428-436 ◽  
Author(s):  
Ichiji Wakabayashi ◽  
Megumi Kanda ◽  
Nobuyasu Miki ◽  
Reiko Demura ◽  
Kazuo Shizume

ABSTRACT Effects of chlorpromazine (CPZ) on plasma GH and prolactin levels were observed in conscious rats provided with chronic indwelling right atrial cannulae. The administration of CPZ (200 μg/100 g b.w. iv) suppressed episodic plasma GH burst and resulted in significant elevations of plasma prolactin levels. These were also observed in rats in which two types of hypothalamic deafferentation, i.e. anterior and complete, had been carried out. The data suggest that CPZ acts within the medial basal hypothalamus and inhibits episodic plasma GH secretion. In addition, it is inferred that catecholamines are involved in the generation of episodic plasma GH burst.


1982 ◽  
Vol 94 (1) ◽  
pp. 77-81 ◽  
Author(s):  
M. Kárteszi ◽  
J. Fiók ◽  
G. B. Makara

Growth hormone secretory dynamics were studied in rats sampled through chronic indwelling right atrial cannulae at time-intervals ranging from 2 days to 2 months after placing an anterolateral cut (ALC) around the medial-basal hypothalamus (MBH). The episodic secretion normally occurring in the control animals could not be seen in the rats with an ALC. Instead of the usual high bursts and low trough levels occurring between 09.00 and 13.00 h in the controls, the operated animals had fairly constant plasma GH levels with only minor fluctuations at all postoperative time-points studied. These results suggest that (1) the isolated MBH is incapable of maintaining the episodic secretion of GH and (2) the pulsatile hormone release is dependent on neural pathways entering the MBH from an anterolateral direction.


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