Platelet Alpha-2 Adrenergic Receptor Binding and Plasma Free 3-Methoxy-4-hydroxyphenyl-ethylene Glycol in Depressed Patients before and after Treatment with Mianserin

1992 ◽  
Vol 25 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Motohisa Kaneko ◽  
Tomoyuki Kanno ◽  
Kyoichi Honda ◽  
Hirobumi Mashiko ◽  
Nobuyoshi Oosuga ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Receptor Binding ◽  
Adrenergic Receptor ◽  
Depressed Patients ◽  
Before And After

A CONTROLLED ETHOLOGICAL STUDY OF DEPRESSED PATIENTS (P) BEFORE AND AFTER FORCED WAKEFULNESS (FW)

1992 ◽  
Vol 15 ◽  
pp. 180B
Author(s):  
A. K. Dixon ◽  
L. C. Huber ◽  
H. U. Fisch ◽  
Sandoz Research Institute
Keyword(s):  
Depressed Patients ◽  
Before And After ◽  
Ethological Study

Increased alpha 1-adrenergic vascular sensitivity during development of hypertension in conscious dogs

1993 ◽  
Vol 264 (4) ◽  
pp. H1259-H1268 ◽  
Author(s):  
N. Uemura ◽  
D. E. Vatner ◽  
Y. T. Shen ◽  
J. Wang ◽  
S. F. Vatner
Keyword(s):  
Adrenergic Receptor ◽  
Peripheral Resistance ◽  
Aortic Pressure ◽  
Conscious Dogs ◽  
Aortic Tissue ◽  
Ang Ii ◽  
Receptor Density ◽  
Adrenergic Stimulation ◽  
Before And After ◽  
Vascular Responsiveness

The goal of this study was to determine whether enhanced vascular responsiveness during the development of perinephritic hypertension is selective or nonspecific. The effects of graded infusions of norepinephrine (NE), phenylephrine (PE), angiotensin II (ANG II), and vasopressin (VP) were examined on mean arterial pressure, total peripheral resistance (TPR), and aortic pressure-diameter relationships in conscious dogs. NE increased TPR significantly greater (P < 0.01) in hypertension than normotension, as did PE infusion, whereas ANG II and VP increased TPR similarly before and after hypertension. Analysis of aortic pressure-diameter relationships also demonstrated significant (P < 0.05) shifts in response to NE and PE, but not ANG II and VP, during the development of hypertension. In normotensive dogs, low doses of ANG II infusion also enhanced the vasoconstrictor response not only to NE and PE but also to VP. In contrast to what was observed in hypertension, in the presence of ANG II infusion after ganglionic blockade, enhanced responses to PE and NE were no longer observed. The alpha 1-adrenergic receptor density in membrane preparations from aortic tissue, as determined by [3H]prazosin binding, was higher (P < 0.05) in hypertensive dogs than control dogs. Thus the vascular responsiveness in the aorta and resistance vessels is enhanced to alpha 1-adrenergic stimulation, but not to all vasoconstrictors, during developing perinephritic hypertension. The mechanism appears to involve increased alpha 1-adrenergic receptor density.

α2-Adrenergic receptor binding in human platelets: Alterations during the menstrual cycle

1983 ◽  
Vol 34 (1) ◽  
pp. 90-96 ◽  
Author(s):  
Susan B Jones ◽  
David B Bylund ◽  
Clarice A Rieser ◽  
Walid O Shekim ◽  
John A Byer ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Receptor Binding ◽  
Adrenergic Receptor ◽  
Human Platelets

α2-Adrenergic receptor binding in canine Purkinje fibers

FEBS Letters ◽  
1996 ◽  
Vol 380 (1-2) ◽  
pp. 39-43 ◽  
Author(s):  
Hon-Chi Lee ◽  
Ricardo A. Samson ◽  
John J. Cai
Keyword(s):  
Receptor Binding ◽  
Adrenergic Receptor ◽  
Purkinje Fibers
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