Effect of Therapy with Oxygen under High Pressure on Regional Cerebral Blood Flow in the Interval Form of Carbon Monoxide Poisoning: Observation from Subtraction of Technetium-99m HMPAO SPECT Brain Imaging

1991 ◽  
Vol 31 (6) ◽  
pp. 380-383 ◽  
Author(s):  
Yoshiki Maeda ◽  
Yasuhiro Kawasak ◽  
Itsuki Jibiki ◽  
Nariyoshi Yamaguchi ◽  
Hiroshi Matsuda ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
High Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Brain Imaging ◽  
Regional Cerebral Blood Flow ◽  
Carbon Monoxide Poisoning ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Effect Of Therapy

Regional cerebral blood flow of acute carbon monoxide poisoning in cats

1987 ◽  
Vol 72 (4) ◽  
pp. 389-393 ◽  
Author(s):  
R. Okeda ◽  
T. Matsuo ◽  
T. Kuroiwa ◽  
M. Nakai ◽  
T. Tajima ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Carbon Monoxide Poisoning ◽  
Regional Cerebral Blood ◽  
Acute Carbon Monoxide Poisoning

Vorläufige Ergebnisse von 99mTc-HMPAO-SPECT-Untersuchungen bei endogenen Psychosen

1989 ◽  
Vol 28 (03) ◽  
pp. 88-91
Author(s):  
J. Schröder ◽  
H. Henningsen ◽  
H. Sauer ◽  
P. Georgi ◽  
K.-R. Wilhelm
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regions Of Interest ◽  
Post Mortem ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Endogenous Psychoses ◽  
The Brain ◽  
99Mtc Hmpao

18 psychopharmacologically treated patients (7 schizophrenics, 5 schizoaffectives, 6 depressives) were studied using 99mTc-HMPAO-SPECT of the brain. The regional cerebral blood flow was measured in three transversal sections (infra-/supraventricular, ventricular) within 6 regions of interest (ROI) respectively (one frontal, one parietal and one occipital in each hemisphere). Corresponding ROIs of the same section in each hemisphere were compared. In the schizophrenics there was a significantly reduced perfusion in the left frontal region of the infraventricular and ventricular section (p < 0.02) compared with the data of the depressives. The schizoaffectives took an intermediate place. Since the patients were treated with psychopharmaca, the result must be interpreted cautiously. However, our findings seem to be in accordance with post-mortem-, CT- and PET-studies presented in the literature. Our results suggest that 99mTc-HMPAO-SPECT may be helpful in finding cerebral abnormalities in endogenous psychoses.

Tc-99m HMPAO/SPECT Determination of Regional Cerebral Blood Flow Changes in Schizophrenics

1990 ◽  
Vol 15 (12) ◽  
pp. 904-907 ◽  
Author(s):  
BELKIS ERBAS ◽  
HAKAN KUMBASAR ◽  
G??NAYDIN ERBENGI ◽  
COSKUN BEKDIK
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Flow Changes

Changes in Regional Cerebral Blood Flow Related to Line Bisection Discrimination and Visual Attention Using HMPAO-SPECT

NeuroImage ◽  
1997 ◽  
Vol 6 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Randolph S. Marshall ◽  
Ronald M. Lazar ◽  
Ronald L. Van Heertum ◽  
Peter D. Esser ◽  
Gerard M. Perera ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Visual Attention ◽  
Regional Cerebral Blood Flow ◽  
Line Bisection ◽  
Regional Cerebral Blood ◽  
Hmpao Spect

Reduced regional cerebral blood flow measured by 99mTc-HMPAO SPECT in microgravity simulated by 5-day dry immersion

2021 ◽  
Author(s):  
Laurent Guillon ◽  
Marc Kermorgant ◽  
Thomas Charvolin ◽  
Fabrice Bonneville ◽  
Marie-Pierre Bareille ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Peak Level ◽  
Emission Computed Tomography ◽  
Regional Cerebral Blood ◽  
Caudate Nuclei ◽  
Dry Immersion ◽  
Hmpao Spect ◽  
Significant Difference

Abstract Purpose Neuro-ophthalmological changes defined as spaceflight-associated neuro-ocular syndrome have been reported after long duration space flights. The pathophysiology of this syndrome remains unclear, with the possible involvement of elevated intracranial pressure. Changes in blood flow in the brain, evaluated indirectly by Doppler, have been reported in flight. However, the effects of microgravity on regional cerebral blood flow (rCBF) are not known. We therefore investigated changes in rCBF in a 5-day dry immersion (DI) model. Moreover, we tested thigh cuffs as a countermeasure to prevent potential microgravity-induced modifications in rCBF.Methods 18 healthy male participants underwent 5-day DI with or without a thigh cuffs countermeasure. They were randomly allocated to a control (n = 9) or cuffs (n = 9) group. rCBF was measured 4 days before DI (Pre-DI) and at the end of the fifth day of DI (Post-DI), using single-photon emission computed tomography (SPECT) with radiopharmaceutical 99mTc-hexamethyl propylene amine oxime (HMPAO). SPECT images were processed using statistical parametric mapping (SPM12) software.Results At DI5, we observed a significant decrease in rCBF in 32 cortical and subcortical patterns, with greater hypoperfusion in the occipital region (occipital peak level: z = 4.51, puncorr < 0.001) and basal ganglia (putamen peak level: z = 4.71, puncorr < 0.001; caudate nuclei peak level: z = 3.80, puncorr < 0.001). No significant difference was found between the control and cuffs groups on variations in rCBF at DI5.Conclusion 5-day DI induces a relative decrease in rCBF in cortical and subcortical regions. Nevertheless, the consequences of this decrease for brain function and mechanisms need further investigation.

Regional cerebral blood flow in endogenous psychoses: A Tc-99m HMPAO-SPECT pilot study

1989 ◽  
Vol 29 (3) ◽  
pp. 331-333 ◽  
Author(s):  
J. Schroeder ◽  
H. Sauer ◽  
K.-R. Wilhelm ◽  
T. Niedermeier ◽  
P. Georgi
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Pilot Study ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Endogenous Psychoses
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