Observations on the Interhemispheric Transmission of Information in 9 Patients with Corpus callosum Defect

1970 ◽  
Vol 4 (3) ◽  
pp. 129-147 ◽  
Author(s):  
H.J. Lehmann ◽  
H. Lampe
Keyword(s):  
Corpus Callosum ◽  
Transmission Of Information ◽  
Interhemispheric Transmission

Interhemispheric Transmission of Visuomotor Information in Humans: fMRI Evidence

2002 ◽  
Vol 88 (2) ◽  
pp. 1051-1058 ◽  
Author(s):  
M. Tettamanti ◽  
E. Paulesu ◽  
P. Scifo ◽  
A. Maravita ◽  
F. Fazio ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Visual Information ◽  
Human Subjects ◽  
Conduction Time ◽  
Clear Cut ◽  
Cortical Areas ◽  
Poffenberger Paradigm ◽  
Interhemispheric Transmission ◽  
Hemispheric Activation ◽  
Normal Human

Normal human subjects underwent functional magnetic resonance imaging (fMRI) while performing a simple visual manual reaction-time (RT) task with lateralized brief stimuli, the so-called Poffenberger's paradigm. This paradigm was employed to measure interhemispheric transmission (IT) time by subtracting mean RT for the uncrossed hemifield-hand conditions, that is, those conditions not requiring an IT, from the crossed hemifield-hand conditions, that is, those conditions requiring an IT to relay visual information from the hemisphere of entry to the hemisphere subserving the response. The obtained difference is widely believed to reflect callosal conduction time, but so far there is no direct physiological evidence in humans. The aim of our experiment was twofold: first, to test the hypothesis that IT of visuomotor information requires the corpus callosum and to identify the cortical areas specifically activated during IT. Second, we sought to discover whether IT occurs mainly at premotor or perceptual stages of information processing. We found significant activations in a number of frontal, parietal, and temporal cortical areas and in the genu of the corpus callosum. These activations were present only in the crossed conditions and therefore were specifically related to IT. No selective activation was present in the uncrossed conditions. The location of the activated callosal and cortical areas suggests that IT occurs mainly, but not exclusively, at premotor level. These results provide clear cut evidence in favor of the hypothesis that the crossed-uncrossed difference in the Poffenberger paradigm depends on IT rather than on a differential hemispheric activation.

Changes in Alpha Band Eeg Activity in the Frontal Area after Stimulation with Music of Different Affective Content

1997 ◽  
Vol 84 (2) ◽  
pp. 515-526 ◽  
Author(s):  
Tatsuya Iwaki ◽  
Mitsuo Hayashi ◽  
Tadao Hori
Keyword(s):  
Close Relationships ◽  
Frontal Area ◽  
Alpha Band ◽  
Baseline Session ◽  
Eeg Activity ◽  
Affective Content ◽  
Interhemispheric Coherence ◽  
Transmission Of Information ◽  
Interhemispheric Transmission

This study investigated the stimulating effects of music. Twelve-channel EEGs (Fp1, Fp2, F7, F8, Fz, C3, C4, Pz, T5, T6, O1, O2) were recorded on 10 students during periods of baseline, premusic rest, music (stimulating or calming), and postmusic rest. The amplitude of the alpha-2 (9.6 to 11.4 Hz) band was lower during the rest session than that during the baseline session. In the music period the amplitude of alpha-2 band increased during both the stimulating and calm music. The frontal interhemispheric coherence values (F7-F8) of the alpha-2 band increased during the stimulating music session, while the coherence values did not change during the calm music. These findings implied close relationships between the interhemispheric transmission of information in the frontal areas and positive attention to stimulating music.

Sensory and Motor Interhemispheric Integration after Section of Different Portions of the Anterior Corpus Callosum in Nonepileptic Patients

Neurosurgery ◽  
2005 ◽  
Vol 57 (1) ◽  
pp. 50-59 ◽  
Author(s):  
Stéphanie Caillé ◽  
Hannelore C. Sauerwein ◽  
Alessandra Schiavetto ◽  
Jean-Guy Villemure ◽  
Maryse Lassonde
Keyword(s):  
Corpus Callosum ◽  
Bimanual Coordination ◽  
Motor Coordination ◽  
Response Times ◽  
Motor Planning ◽  
The Body ◽  
Anterior Portion ◽  
Interhemispheric Transmission ◽  
Intraventricular Cyst ◽  
Anterior Body

Abstract OBJECTIVE: We evaluated somatosensory and motor interhemispheric integration in four patients who underwent transection of different portions of the anterior corpus callosum (CC) for removal of an intraventricular cyst. The study goal was to relate their performances to the topographical organization of the CC. METHODS: Experimental tasks included bimanual coordination, tactile cross-localization, and intermanual and interfield comparisons of somesthetic information. Response accuracy and response times were measured. In addition, interhemispheric transmission times were obtained in the somesthetic modality. RESULTS: Section of the middle portion of the genu caused a deficit in motor coordination, which was absent in patients with more posteriorly located lesions, whereas section of more rostral portions of the genu seemed to interfere with motor planning. The most posterior section in our sample, including the anterior portion of the body of the corpus, abolished interhemispheric transfer of simple somesthetic information (perception of touch) but not tactile discrimination (intermanual comparisons of shapes). We speculate that more complex somesthetic information is transferred through the caudal region of the body of the CC, which was spared in all patients. Thus, it seems that section of different portions of the anterior CC (genu and anterior body) produces specific deficits in interhemispheric integration in the motor and somesthetic modalities. These deficits are consistent with the anteroposterior topography of anterior callosal fibers. CONCLUSION: The specific disconnections deficits observed in this study may provide the surgeon with information regarding the consequences of anterior callosotomy and allow for remedial measures to be implemented if required.

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