Simple Stratification of Survival Using Bone Scan and Serum C-Reactive Protein in Prostate Cancer Patients with Metastases

2008 ◽  
Vol 80 (2) ◽  
pp. 129-133 ◽  
Author(s):  
Jun Nakashima ◽  
Eiji Kikuchi ◽  
Akira Miyajima ◽  
Ken Nakagawa ◽  
Mototsugu Oya ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Bone Scan ◽  
C Reactive Protein ◽  
Reactive Protein

1020: Simple Stratification of Survival Using Bone Scan and Serum C-Reactive Protein in Prostate Cancer Patients with Metastases

2007 ◽  
Vol 177 (4S) ◽  
pp. 336-337
Author(s):  
Jun Nakashima ◽  
Eiji Kikuchi ◽  
Akira Miyajima ◽  
Ken Nakagawa ◽  
Mototsugu Oya ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Bone Scan ◽  
C Reactive Protein ◽  
Reactive Protein

Relationship between biological and self-reported measures of stress among informal caregivers of patients with prostate cancer

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 18506-18506
Author(s):  
W. P. Witt ◽  
S. Pickard ◽  
T. Kuzel ◽  
T. McDade ◽  
S. Perry ◽  
...  
Keyword(s):  
Mental Health ◽  
Prostate Cancer ◽  
Cancer Patients ◽  
Epstein Barr Virus ◽  
Informal Caregivers ◽  
C Reactive Protein ◽  
Barr Virus ◽  
Reactive Protein ◽  
Biological Stress ◽  
Epstein Barr

18506 Background: Informal caregivers of prostate cancer patients often experience chronic psychological stress that may adversely impact their physical and mental health, and their ability to care for their families and the patient. This study aims to determine the association between perceived and biological stress among informal caregivers of prostate cancer patients. Methods: A total of 24 informal caregivers of prostate cancer patients were recruited from both the Jesse Brown VA Center (Lakeside and Westside, Chicago) and the Robert H. Lurie Comprehensive Cancer Center at Northwestern University. Caregivers completed self-reported measures of stress, somatization, life events, burden, health status (SF-36) and mental health. Capillary blood spot samples from caregivers were used to examine two measures of biological stress, Epstein-Barr virus antibody titer and C-reactive protein. Results: Informal caregivers had a mean age of 63 years and were mostly female and spouses of patients with prostate cancer. Many had preexisting co-morbidities, including 45.8% with hypertension, 45.8% with arthritis, and 33.3% with diabetes. Nearly 30% had been hospitalized in the last 12 months. 33.3% of caregivers experienced at least one major life event in the last year and 62.5% had symptoms of somatization illness. Caregivers with symptoms of somatization illness had higher mean Epstein-Barr antibody titers as compared with those without symptoms (Mean EBV antibody titer: 198.3 versus 141.8, respectively (p < 0.05)). Caregiver-reported measures were not correlated with C-reactive protein levels. Caregivers with higher levels of strain perceived more stress in their lives (p < 0.05), but showed relatively high self-esteem (mean = 30.6, SD = 2.8, on a 7–35 scale). Conclusions: These preliminary findings suggest that informal caregivers who report symptoms of somatization illness exhibit signs of relative suppression of the cell-mediated immune processes as a result of the reactivation of the Epstein-Barr virus. Final analyses will be conducted that control for potential confounders and will further elucidate if caregiver stress is associated with suppression of the immune system. No significant financial relationships to disclose.

scholarly journals Pooled Analysis of C-Reactive Protein Levels and Mortality in Prostate Cancer Patients

2015 ◽  
Vol 13 (4) ◽  
pp. e217-e221 ◽  
Author(s):  
Julie N. Graff ◽  
Tomasz M. Beer ◽  
Bian Liu ◽  
Guru Sonpavde ◽  
Emanuela Taioli
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Pooled Analysis ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

The elevated C-reactive protein level is associated with poor prognosis in prostate cancer patients treated with radiotherapy

2015 ◽  
Vol 51 (5) ◽  
pp. 610-619 ◽  
Author(s):  
Eva-Maria Thurner ◽  
Sabine Krenn-Pilko ◽  
Uwe Langsenlehner ◽  
Tatjana Stojakovic ◽  
Martin Pichler ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Protein Level ◽  
Poor Prognosis ◽  
C Reactive Protein ◽  
Reactive Protein

PD-0303: Elevated C-reactive protein level predicts poor prognosis in prostate cancer patients treated with radiotherapy

2014 ◽  
Vol 111 ◽  
pp. S118
Author(s):  
E. Thurner ◽  
S. Krenn-Pilko ◽  
M. Pichler ◽  
A. Gerger ◽  
U. Langsenlehner ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Protein Level ◽  
Poor Prognosis ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Changes in the rate of PSA progression and the level of alkaline phosphatase during high dose vitamin C treatment of patients with prostate cancer

2017 ◽  
Vol 7 (7) ◽  
pp. 511
Author(s):  
Nina Mikirova ◽  
Ronald Hunninghake
Keyword(s):  
Prostate Cancer ◽  
Alkaline Phosphatase ◽  
Vitamin C ◽  
Cancer Patients ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
High Dose ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
High Dose Vitamin

Introduction: Intravenously administered vitamin C (IVC) may have anti-cancer and anti-inflammatory properties. Many studies demonstrated evidence of a good safety profile of IVC treatments and improvement of the quality of life in cancer patients. IVC has been proposed as a treatment for cancer as an adjuvant in conjunction with other therapies. To investigate high dose ascorbic acid potential in treating prostate cancer, a retrospective study was conducted using clinical data from the Riordan Clinic database (1994-2015).Methods: We collected data, when available, on the following patient characteristics at diagnosis and during the courses of IVC therapy: age, tumor stage, Gleason score, serum prostate specific antigen (PSA) and alkaline phosphatase (ALP) levels, and location of metastases. In particular, PSA, ALP, and C-reactive protein (CRP) levels are analyzed in prostate cancer patients given IVC therapy during several years. Results: We found that PSA, CRP, and ALP correlate with tumor staging as measured by Gleason scores. Moreover, peak plasma ascorbate levels attained during the patients first IVC infusions are reduced in patients with elevated PSA and CRP levels. Tracking the changes in PSA and ALP with time in patients for whom data are available indicates that the rate of increase in these variables over time can be reduced by incorporating IVC therapy and by increasing the frequency of IVC treatments.Conclusion:  There appeared to be a relation between the frequency of IVC treatments and the rate of PSA change, with PSA rate of growth decreasing as the frequency of IVC increases.  Further research into the use of IVC in prostate cancer patients is warranted.Key words: High dose vitamin C, prostate cancer, prostate specific antigen, alkaline phosphatase, C-reactive protein. 

Serum C-reactive protein acted as a prognostic biomarker for overall survival in metastatic prostate cancer patients

Tumor Biology ◽  
2014 ◽  
Vol 36 (2) ◽  
pp. 669-673 ◽  
Author(s):  
Liuyu Xu ◽  
Qingli Zhao ◽  
Shengliang Huang ◽  
Shun Li ◽  
Jin Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Overall Survival ◽  
Cancer Patients ◽  
Metastatic Prostate Cancer ◽  
Prognostic Biomarker ◽  
C Reactive Protein ◽  
Reactive Protein

Tumoral C-reactive protein and nuclear factor kappa-B expression are associated with clinical outcome in patients with prostate cancer

2012 ◽  
Vol 10 (2) ◽  
pp. 91-99 ◽  
Author(s):  
Pamela McCall ◽  
Jamie Catlow ◽  
Peter A McArdle ◽  
Donald C McMillan ◽  
Joanne Edwards
Keyword(s):  
Prostate Cancer ◽  
Clinical Outcome ◽  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Nuclear Factor Kappa

639 RISK OF PROSTATE CANCER IS NOT ASSOCIATED WITH LEVELS OF C-REACTIVE PROTEIN AND OTHER COMMONLY USED MARKERS OF INFLAMMATION

2011 ◽  
Vol 10 (2) ◽  
pp. 207
Author(s):  
Hemelrijck M.J.J. Van ◽  
I. Jugner ◽  
G. Walldius ◽  
H. Garmo ◽  
E. Binda ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Markers Of Inflammation
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