Influence of Epidermal Growth Factor on the Maturation of Fetal Rat Brain Cells in Aggregate Culture

1989 ◽  
Vol 11 (1) ◽  
pp. 30-40 ◽  
Author(s):  
F. Monnet-Tschudi ◽  
P. Honegger
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Rat Brain ◽  
Brain Cells ◽  
Fetal Rat ◽  
Aggregate Culture ◽  
Epidermal Growth ◽  
Fetal Rat Brain

scholarly journals Epidermal Growth Factor Immunoreactive Material in the Rat Brain

1989 ◽  
Vol 264 (18) ◽  
pp. 10447-10450
Author(s):  
R P Schaudies ◽  
E L Christian ◽  
C R Savage
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Rat Brain ◽  
Immunoreactive Material ◽  
Epidermal Growth

Development of Monoamine Oxidase and Aldehyde Dehydrogenase in Reaggregating Cultures of Fetal Rat Brain Cells

1989 ◽  
Vol 16 (3) ◽  
pp. 281-286
Author(s):  
Olof Tottmar ◽  
Maria Söderbäck ◽  
Anders Aspberg
Keyword(s):  
Monoamine Oxidase ◽  
Rat Brain ◽  
Aldehyde Dehydrogenase ◽  
Brain Cells ◽  
Mao B ◽  
Adult Rat ◽  
Fetal Rat ◽  
Adult Rat Brain ◽  
Mao A ◽  
Fetal Rat Brain

The development of monoamine oxidase (MAO) and aldehyde dehydrogenase (ALDH) in reaggregation cultures of fetal rat brain cells was compared with that of enzymatic markers for glial and neuronal cells. Only MAO-A was detected in the cultures during the first week, but, during the following three weeks, the activity of MAO-B increased more rapidly than that of MAO-A. The ratio MAO-A/MAO-B in four-week aggregates was close to that found in the adult rat brain. The activity of ALDH started to increase rapidly after 15 days, and the developmental pattern was intermediate to those of the glial and neuronal markers. The activity after four weeks was close to that found in the adult rat brain. Epidermal growth factor (EGF) caused a slight decrease in the activities of the low-Km ALDH (after four weeks) and the neuronal marker, choline acetyltransferase (after two weeks), whereas the other markers were not affected. By contrast, the activities of MAO-A and MAO-B were greatly increased during almost the entire culture period. It is suggested that this effect of EGF was the result of increased mitotic activity and/or biochemical differentiation of other cell types present in the cell aggregates, e.g. capillary endothelial cells.

scholarly journals Influence of Epidermal Growth Factor on Fetal Rat Lung Development in Vitro

1986 ◽  
Vol 20 (5) ◽  
pp. 473-477 ◽  
Author(s):  
Lan Gross ◽  
Diane W Dynia ◽  
Seamus A Rooney ◽  
Douglas A Smart ◽  
Joseph B Warshaw ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Lung Development ◽  
Rat Lung ◽  
Fetal Rat ◽  
Fetal Rat Lung ◽  
Epidermal Growth ◽  
Development In Vitro

Expression of FcIgG Receptors on Cultured Fetal Rat Brain Cells

1983 ◽  
Vol 70 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Sylvi Aanderud ◽  
Johan Lillehaug ◽  
Olav Tønder ◽  
Ole Didrik Laerum
Keyword(s):  
Rat Brain ◽  
Brain Cells ◽  
Fetal Rat ◽  
Fetal Rat Brain
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