From Molecular Biology to Targeted Therapies for Hepatocellular Carcinoma: The Future Is Now

Oncology ◽  
2007 ◽  
Vol 72 (1) ◽  
pp. 30-44 ◽  
Author(s):  
Roberta W.C. Pang ◽  
Ronnie T.P. Poon
Keyword(s):  
Hepatocellular Carcinoma ◽  
Molecular Biology ◽  
Targeted Therapies ◽  
The Future

Targeted Therapies in Hepatocellular Carcinoma

2014 ◽  
Vol 21 (8) ◽  
pp. 966-974 ◽  
Author(s):  
F. Bronte ◽  
G. Bronte ◽  
S. Cusenza ◽  
E. Fiorentino ◽  
C. Rolfo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Targeted Therapies

Molecular Oncology for the Head and Neck Surgeon

1995 ◽  
Vol 112 (5) ◽  
pp. P88-P89
Author(s):  
Norris K. Lee
Keyword(s):  
Head And Neck Cancer ◽  
Molecular Biology ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Cancer Model ◽  
Educational Objectives ◽  
Molecular Oncology ◽  
The Future ◽  
Biological Concepts

Educational objectives: To understand basic molecular biological concepts and breakthroughs as they apply to the head and neck cancer model and to envision the future of head and neck cancer treatment, within the context of molecular biology.

scholarly journals Genomic Biomarkers of Meningioma: A Focused Review

2021 ◽  
Vol 22 (19) ◽  
pp. 10222
Author(s):  
Jacob A. Pawloski ◽  
Hassan A. Fadel ◽  
Yi-Wen Huang ◽  
Ian Y. Lee
Keyword(s):  
Targeted Therapies ◽  
Recurrence Risk ◽  
Tumor Location ◽  
Genetic Mutations ◽  
Low Grade ◽  
Diverse Group ◽  
The Future ◽  
Genetic Landscape ◽  
The Impact ◽  
The Way

Meningiomas represent a phenotypically and genetically diverse group of tumors which often behave in ways that are not simply explained by their pathologic grade. The genetic landscape of meningiomas has become a target of investigation as tumor genomics have been found to impact tumor location, recurrence risk, and malignant potential. Additionally, targeted therapies are being developed that in the future may provide patients with personalized chemotherapy based on the genetic aberrations within their tumor. This review focuses on the most common genetic mutations found in meningiomas of all grades, with an emphasis on the impact on tumor location and clinically relevant tumor characteristics. NF-2 and the non-NF-2 family of genetic mutations are summarized in the context of low-grade and high-grade tumors, followed by a comprehensive discussion regarding the genetic and embryologic basis for meningioma location and phenotypic heterogeneity. Finally, targeted therapies based on tumor genomics currently in use and under investigation are reviewed and future avenues for research are suggested. The field of meningioma genomics has broad implications on the way meningiomas will be treated in the future, and is gradually shifting the way clinicians approach this diverse group of tumors.

Life as It Could Be

2020 ◽  
pp. 101-114
Author(s):  
Luis Campos
Keyword(s):  
Synthetic Biology ◽  
Molecular Biology ◽  
The Future ◽  
Forms Of Life ◽  
Life On Earth ◽  
The Universe

This chapter explores the intersection between two related fields: synthetic biology and astrobiology. Pushing the engineering of life past traditional limits in molecular biology and expanding the envelope of life to forms never before extant, synthetic biologists are now beginning to design experimental ways of getting at what astrobiologists have long suspected: that the life known here on Earth is but a subset of vast combinatorial possibilities in the universe. The resonances between the future engineered possibilities of this world and speculations about possible biologies on habitable others are not merely happenstance. Indeed, there is a curious and compelling deeper history interlinking scientific speculation about new forms of life elsewhere in the universe with visions for the human-directed engineering of new forms of life on Earth. For decades, the astrobiological and the synthetic biological have mutually inspired each other and overlapped in powerful genealogical ways.

192 New targeted therapies strategies in hepatocellular carcinoma - In vitro studies

2010 ◽  
Vol 8 (7) ◽  
pp. 64-65
Author(s):  
A.M. Araújo ◽  
S. Sousa Neves ◽  
A.L. Ferreira ◽  
J.D. Branco ◽  
A.B. Sarmento Ribeiro ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Targeted Therapies ◽  
In Vitro Studies
Sign in / Sign up

Export Citation Format

Share Document