Juvenile Hormone, Behavioral Maturation, and Brain Structure in the Honey Bee

1996 ◽  
Vol 18 (1-2) ◽  
pp. 102-114 ◽  
Author(s):  
Susan E. Fahrbach ◽  
Gene E. Robinson
Keyword(s):  
Juvenile Hormone ◽  
Honey Bee ◽  
Brain Structure ◽  
Behavioral Maturation

scholarly journals Juvenile hormone pathway in honey bee larvae: A source of possible signal molecules for the reproductive behavior of Varroa destructor

2020 ◽  
Author(s):  
Cristian M. Aurori ◽  
Alexandru‐Ioan Giurgiu ◽  
Benjamin H. Conlon ◽  
Chedly Kastally ◽  
Daniel S. Dezmirean ◽  
...  
Keyword(s):  
Juvenile Hormone ◽  
Honey Bee ◽  
Reproductive Behavior ◽  
Varroa Destructor ◽  
Signal Molecules ◽  
Honey Bee Larvae

Sex-specific developmental profiles of juvenile hormone synthesis in honey bee larvae

1993 ◽  
Vol 202 (3) ◽  
pp. 176-180 ◽  
Author(s):  
Klaus Hartfelder ◽  
Sibele Oliveira Tozetto ◽  
Anna Rachinsky
Keyword(s):  
Juvenile Hormone ◽  
Honey Bee ◽  
Hormone Synthesis ◽  
Developmental Profiles ◽  
Honey Bee Larvae

scholarly journals The transcriptomic signature of low aggression honey bees resembles a response to infection

2020 ◽  
Author(s):  
Clare C Rittschof ◽  
Benjamin E.R. Rubin ◽  
Joseph H. Palmer
Keyword(s):  
Health Outcomes ◽  
Honey Bee ◽  
Fat Body ◽  
Physiological State ◽  
Acute Infection ◽  
Differentially Expressed ◽  
Molecular Response ◽  
Transcriptomic Signature ◽  
Behavioral Maturation ◽  
The Brain

Abstract Background: Behavior reflects an organism's health status. Many organisms display a generalized suite of behaviors that indicate infection or predict infection susceptibility. We apply this concept to honey bee aggression, a behavior that has been associated with positive health outcomes in previous studies. We sequenced the transcriptomes of the brain, fat body, and midgut of adult sibling worker bees who developed as pre-adults in relatively high versus low aggression colonies. Previous studies showed that this pre-adult experience impacts both aggressive behavior and resilience to pesticides. We performed enrichment analyses on differentially expressed genes to determine whether variation in aggression resembles the molecular response to infection. We further assessed whether the transcriptomic signature of aggression in the brain is similar to the neuromolecular response to acute predator threat, exposure to a high-aggression environment as an adult, or adult behavioral maturation. Results: Across all three tissues assessed, genes that are differentially expressed as a function of aggression significantly overlap with genes whose expression is modulated by a variety of pathogens and parasitic feeding. In the fat body, and to some degree the midgut, our data specifically support the hypothesis that low aggression resembles a diseased or parasitized state. However, we find little evidence of active infection in individuals from the low aggression group. We also find little evidence that the brain molecular signature of aggression is enriched for genes modulated by social cues that induce aggression in adults. However, we do find evidence that genes associated with adult behavioral maturation are enriched in our brain samples. Conclusions: Results support the hypothesis that low aggression resembles a molecular state of infection. This pattern is most robust in the peripheral fat body, an immune responsive tissue in the honey bee. We find no evidence of acute infection in bees from the low aggression group, suggesting the physiological state characterizing low aggression may instead predispose bees to negative health outcomes when they are exposed to additional stressors. The similarity of molecular signatures associated with the seemingly disparate traits of aggression and disease suggests that these characteristics may, in fact, be intimately tied.

scholarly journals Transcriptional Control of Honey Bee (Apis mellifera) Major Royal Jelly Proteins by 20-Hydroxyecdysone

Insects ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 122 ◽  
Author(s):  
Paul Winkler ◽  
Frank Sieg ◽  
Anja Buttstedt
Keyword(s):  
Gene Expression ◽  
Apis Mellifera ◽  
Juvenile Hormone ◽  
Honey Bee ◽  
Honey Bees ◽  
Transcriptional Control ◽  
Royal Jelly ◽  
Adult Worker ◽  
Gene Expression Dynamics

One of the first tasks of worker honey bees (Apis mellifera) during their lifetime is to feed the larval offspring. In brief, young workers (nurse bees) secrete a special food jelly that contains a large amount of unique major royal jelly proteins (MRJPs). The regulation of mrjp gene expression is not well understood, but the large upregulation in well-fed nurse bees suggests a tight repression until, or a massive induction upon, hatching of the adult worker bees. The lipoprotein vitellogenin, the synthesis of which is regulated by the two systemic hormones 20-hydroxyecdysone and juvenile hormone, is thought to be a precursor for the production of MRJPs. Thus, the regulation of mrjp expression by the said systemic hormones is likely. This study focusses on the role of 20-hydroxyecdysone by elucidating its effect on mrjp gene expression dynamics. Specifically, we tested whether 20-hydroxyecdysone displayed differential effects on various mrjps. We found that the expression of the mrjps (mrjp1–3) that were finally secreted in large amounts into the food jelly, in particular, were down regulated by 20-hydroxyecdysone treatment, with mrjp3 showing the highest repression value.

Hormonal regulation of behavioural development in the honey bee is based on changes in the rate of juvenile hormone biosynthesis

1991 ◽  
Vol 37 (10) ◽  
pp. 733-741 ◽  
Author(s):  
Zhi-Yong Huang ◽  
Gene E. Robinson ◽  
Stephen S. Tobe ◽  
Koichiro J. Yagi ◽  
Colette Strambi ◽  
...  
Keyword(s):  
Juvenile Hormone ◽  
Honey Bee ◽  
Hormonal Regulation ◽  
Behavioural Development ◽  
Juvenile Hormone Biosynthesis ◽  
Hormone Biosynthesis

scholarly journals The transcriptomic signature of low aggression honey bees resembles a response to infection

2019 ◽  
Author(s):  
Clare C Rittschof ◽  
Benjamin E.R. Rubin ◽  
Joseph H. Palmer
Keyword(s):  
Health Outcomes ◽  
Honey Bee ◽  
Fat Body ◽  
Physiological State ◽  
Acute Infection ◽  
Differentially Expressed ◽  
Molecular Response ◽  
Transcriptomic Signature ◽  
Behavioral Maturation ◽  
The Brain

Abstract Background: Behavior reflects an organism's health status. Many organisms display a generalized suite of behaviors that indicate infection or predict infection susceptibility. We apply this concept to honey bee aggression, a behavior that has been associated with positive health outcomes in previous studies. We sequenced the transcriptomes of the brain, fat body, and midgut of adult sibling worker bees who developed as pre-adults in relatively high versus low aggression colonies. Previous studies showed that this pre-adult experience impacts both aggressive behavior and resilience to pesticides. We performed enrichment analyses on differentially expressed genes to determine whether variation in aggression resembles the molecular response to infection. We further assessed whether the transcriptomic signature of aggression in the brain is similar to the neuromolecular response to acute predator threat, exposure to a high-aggression environment as an adult, or adult behavioral maturation. Results: Across all three tissues assessed, genes that are differentially expressed as a function of aggression significantly overlap with genes whose expression is modulated by a variety of pathogens and parasitic feeding. In the fat body, and to some degree the midgut, our data specifically support the hypothesis that low aggression resembles a diseased or parasitized state. However, we find little evidence of active infection in individuals from the low aggression group. We also find little evidence that the brain molecular signature of aggression is enriched for genes modulated by social cues that induce aggression in adults. However, we do find evidence that genes associated with adult behavioral maturation are enriched in our brain samples. Conclusions: Results support the hypothesis that low aggression resembles a molecular state of infection. This pattern is most robust in the peripheral fat body, an immune responsive tissue in the honey bee. We find no evidence of acute infection in bees from the low aggression group, suggesting the physiological state characterizing low aggression may instead predispose bees to negative health outcomes when they are exposed to additional stressors. The similarity of molecular signatures associated with the seemingly disparate traits of aggression and disease suggests that these characteristics may, in fact, be intimately tied.

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