scholarly journals Tissue Inhibitor of Matrix Metalloproteinase-1 in Norepinephrine-Induced Remodeling of the Mouse Heart

2007 ◽  
Vol 20 (6) ◽  
pp. 825-836 ◽  
Author(s):  
Henning Meier ◽  
Jörg Bullinger ◽  
Alexander Deten ◽  
Grit Marx ◽  
Steffen Rabald ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Mouse Heart ◽  
Tissue Inhibitor ◽  
Matrix Metalloproteinase 1

scholarly journals Reference ranges of matrix metalloproteinase-1, -2, -9 and tissue inhibitor of matrix metalloproteinases-1 concentrations in amniotic fluid in physiological pregnancy

2016 ◽  
Vol 62 (1) ◽  
pp. 96-98
Author(s):  
Yu.V. Korenovsky ◽  
O.V. Remneva
Keyword(s):  
Matrix Metalloproteinases ◽  
Matrix Metalloproteinase ◽  
Amniotic Fluid ◽  
Reference Values ◽  
Reference Ranges ◽  
Tissue Inhibitor ◽  
Protein Ratio ◽  
Matrix Metalloproteinase 1 ◽  
Term Labor ◽  
First Stage Of Labor

The aim of this study was to determine reference values of matrix metalloproteinase-1 (MMP-1), MMP-2, MMP-9 and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in the amniotic fluid at the first stage of labor in physiological pregnancy. 89 women at the first stage of term labor have been examined. Samples of amniotic fluid were taken at the first period of labor by vaginal amniotomy. Concentrations ofMMP-1, MMP-2, MMP-9, and TIMP-1 were investigated in amniotic fluid by ELISA kits. We have determined normal concentration ranges for MMP-1, MMP-2, MMP-9, TIMP-1, and ratios of concentrations of MMPs and TIMP-1 (MMP-1/TIMP-1, MMP-2/TIMP-1, MMP-9/TIMP-1) in the amniotic fluid at the first period of labor in physiological pregnancy. These included: MMP-1 - 5.1-16.8 pg/mg of protein, MMP-2 - 238.3-374.1 pg/mg of protein, MMP-9 - 66.1-113.3 pg/mg of protein, TIMP-1 - 4.7-13.6 pg/mg of protein, ratio of MMP-1/TIMP-1 - 0.1-2.2, ratio of MMP-2/TIMP-1 - 19.9-55.7, ratio of MMP-9/TIMP-1 - 4.2-17.2.

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