Risk of Cerebral Infarction, Myocardial Infarction and Vascular Death in Patients with Asymptomatic Carotid Disease, Transient Ischemic Attack and Stroke

1992 ◽  
Vol 2 (1) ◽  
pp. 2-5 ◽  
Author(s):  
J.W. Norris
CJEM ◽  
2016 ◽  
Vol 18 (5) ◽  
pp. 331-339 ◽  
Author(s):  
Gregory W. Hosier ◽  
Stephen J. Phillips ◽  
Steve P. Doucette ◽  
Kirk D. Magee ◽  
Gordon J. Gubitz

AbstractObjectives1) To evaluate whether transient ischemic attack (TIA) management in emergency departments (EDs) of the Nova Scotia Capital District Health Authority followed Canadian Best Practice Recommendations, and 2) to assess the impact of being followed up in a dedicated outpatient neurovascular clinic.MethodsRetrospective chart review of all patients discharged from EDs in our district from January 1, 2011 to December 31, 2012 with a diagnosis of TIA. Cox proportional hazards models, Kaplan-Meier survival curve, and propensity matched analyses were used to evaluate 90-day mortality and readmission.ResultsOf the 686 patients seen in the ED for TIA, 88.3% received computed tomography (CT) scanning, 86.3% received an electrocardiogram (ECG), 35% received vascular imaging within 24 hours of triage, 36% were seen in a neurovascular clinic, and 4.2% experienced stroke, myocardial infarction, or vascular death within 90 days. Rates of antithrombotic use were increased in patients seen in a neurovascular clinic compared to those who were not (94% v. 86.3%, p<0.0001). After adjustment for age, sex, vascular disease risk factors, and stroke symptoms, the risk of readmission for stroke, myocardial infarction, or vascular death was lower for those seen in a neurovascular clinic compared to those who were not (adjusted hazard ratio 0.28; 95% confidence interval 0.08–0.99, p=0.048).ConclusionThe majority of patients in our study were treated with antithrombotic agents in the ED and investigated with CT and ECG within 24 hours; however, vascular imaging and neurovascular clinic follow-up were underutilized. For those with neurovascular clinic follow-up, there was an association with reduced risk of subsequent stroke, myocardial infarction, or vascular death.


Stroke ◽  
2005 ◽  
Vol 36 (12) ◽  
pp. 2748-2755 ◽  
Author(s):  
Emmanuel Touzé ◽  
Olivier Varenne ◽  
Gilles Chatellier ◽  
Séverine Peyrard ◽  
Peter M. Rothwell ◽  
...  

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Mengjiao Wei

 Symptomatic atherosclerotic intracranial artery stenosis often causes ischemic cerebral infarction or transient ischemic attack in the stenosis area. Early detection of cerebral infarction and evaluation of ischemic penumbra and hemodynamics in the infarct area Information plays an extremely important role in clinical treatment and prognosis. This article briefly introduces the application of multimodal MRI in cerebral infarction.


Stroke ◽  
2005 ◽  
Vol 36 (6) ◽  
pp. 1128-1133 ◽  
Author(s):  
Anne L. Abbott ◽  
Brian R. Chambers ◽  
Jacinda L. Stork ◽  
Christopher R. Levi ◽  
Christopher F. Bladin ◽  
...  

Stroke ◽  
2019 ◽  
Vol 50 (12) ◽  
pp. 3393-3399 ◽  
Author(s):  
Marion Boulanger ◽  
Linxin Li ◽  
Shane Lyons ◽  
Nicola G. Lovett ◽  
Magdalena M. Kubiak ◽  
...  

1993 ◽  
Vol 3 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Askiel Bruno ◽  
Lynn Jeffries ◽  
Elizabeth LaKind ◽  
Clifford Qualls

Stroke ◽  
1981 ◽  
Vol 12 (2) ◽  
pp. 167-172 ◽  
Author(s):  
A Murai ◽  
T Tanaka ◽  
T Miyahara ◽  
M Kameyama

2009 ◽  
Vol 12 (3) ◽  
pp. A144-A145
Author(s):  
I Kriszbacher ◽  
I Boncz ◽  
L Gazdag ◽  
A Mátyus ◽  
I Vránics ◽  
...  

Author(s):  
Do Young Kim ◽  
Myung‐Soo Park ◽  
Jong‐Chan Youn ◽  
Sunki Lee ◽  
Jae Hyuk Choi ◽  
...  

Background Cardiovascular disease is an important cause of mortality among survivors of breast cancer (BC). We developed a prediction model for major adverse cardiovascular events after BC therapy, which is based on conventional and BC treatment‐related cardiovascular risk factors. Methods and Results The cohort of the study consisted of 1256 Asian female patients with BC from 4 medical centers in Korea and was randomized in a 1:1 ratio into the derivation and validation cohorts. The outcome measures comprised cardiovascular mortality, myocardial infarction, congestive heart failure, and transient ischemic attack/stroke. To correct overfitting, a penalized Cox proportional hazards regression was performed with a cross‐validation approach. Number of cardiovascular diseases (myocardial infarction, peripheral artery disease, heart failure, and transient ischemic attack/stroke), number of baseline cardiovascular risk factors (hypertension, age ≥60, body mass index ≥30 kg/m 2 , estimated glomerular filtration rate <60 mL/min per 1.73 m 2 , dyslipidemia, and diabetes mellitus), radiation to the left breast, and anthracycline dose per 100 mg/m 2 were included in the risk prediction model. The time‐dependent C‐indices at 3 and 7 years after BC diagnosis were 0.876 and 0.842, respectively, in the validation cohort. Conclusions A prediction score model, including BC treatment‐related risk factors and conventional risk factors, was developed and validated to predict major adverse cardiovascular events in patients with BC. The CHEMO‐RADIAT (congestive heart failure, hypertension, elderly, myocardial infarction/peripheral artery occlusive disease, obesity, renal failure, abnormal lipid profile, diabetes mellitus, irradiation of the left breast, anthracycline dose, and transient ischemic attack/stroke) score may provide overall cardiovascular risk stratification in survivors of BC and can assist physicians in multidisciplinary decision‐making regarding the BC treatment.


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