Noninvasive Screening for Silent Ischemic Heart Disease in Patients with Cerebral Ischemia: Use of Dipyridamole-Thallium Myocardial Imaging

1990 ◽  
Vol 1 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Giuseppe Di Pasguale ◽  
Alvaro Andreoli ◽  
Giancarlo Carini ◽  
Maurizio Dondi ◽  
Stefano Urbinati ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cerebral Ischemia ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Myocardial Imaging ◽  
Dipyridamole Thallium

scholarly journals Platelet Aggregation in Patients with Ischemic Heart Disease, Transient Cerebral Ischemia and Peripheral Thrombo-Atherosclerosis

1977 ◽  
Author(s):  
J. Gormsen ◽  
J. D. Nielsen ◽  
L. A. Andersen
Keyword(s):  
Heart Disease ◽  
Platelet Aggregation ◽  
Cerebral Ischemia ◽  
Ischemic Heart Disease ◽  
Transient Cerebral Ischemia ◽  
Ischemic Heart ◽  
Control Groups ◽  
Normal Women ◽  
Normal Controls

The threshold concentrations of ADP and adrenaline inducing platelet aggregation in vitro were determined in a Payton aggregometer in 90 normal controls, 30 patients with ischemic heart disease (IHS), in 34 with transient cerebral ischemia (TCI) and 22 with peripheral thrombo-atherosclerosis (PTA). The threshold concentrations were significantly lower in normal women ≥ 50 years old than in normal women < 50 years old.Compared with the corresponding control groups significantly lower threshold concentrations were found in following groups of patients: men and women ≥ 50 years with IHS (p < 0.005 and p < 0.001 respectively), men + women < 50 years with IHS (p < 0.05), men + women with TCI (p < 0.01), men + women ≥ 50 years with PTA (p < O.002 and p < 0.001 respectively), men + women < 50 years with PTA (p < 0.005).

Dipyridamole Thallium-201 Perfusion Imaging for the Study of Ischemic Heart Disease in Hemodialysis Patients

1989 ◽  
Vol 12 (12) ◽  
pp. 773-777 ◽  
Author(s):  
R. Marcen ◽  
S. Lamas ◽  
L. Orofino ◽  
C. Quereda ◽  
F. Barcia ◽  
...  
Keyword(s):  
Heart Disease ◽  
Myocardial Perfusion ◽  
Ischemic Heart Disease ◽  
Perfusion Imaging ◽  
Thallium 201 ◽  
Ischemic Heart ◽  
Asymptomatic Patients ◽  
Perfusion Defects ◽  
Myocardial Perfusion Defects ◽  
Dipyridamole Thallium

To assess the usefulness of dipyridamole thallium perfusion imaging in the evaluation of myocardial perfusion in hemodialysis (HD), we studied 29 HD patients divided into three groups: A) 13 patients with clinical angina, B) 8 patients without angina but similar in age, sex, time on HD and hematocrit and C) 8 young asymptomatic patients (mean age 33 ± 9.7 years). Dipyridamole thallium-201 (TI-201) perfusion imaging revealed myocardial perfusion defects in 8 patients (61%) from group A, 4 (50%) from group B and 1 (12.5%) from group C. These defects were localized in the inferior, posterior and septal segments of the left ventricle. Abnormal myocardial perfusion was associated with age over 50 years and aortic calcifications (p < 0.05). Eight patients died within the following four years. All had aortic calcifications (p < 0.001). Our results show that myocardial perfusion defects are frequent even in non-symptomatic HD patients. This suggests that ischemic heart disease could be more frequent than estimated by clinical symptoms alone. TI-201 scintigraphy may be a useful non-invasive procedure in cardiological evaluation of HD patients

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