Different Acute Tolerance Development to EEG, Psychomotor Performance and Subjective Assessment Effects after Two Intermittent Oral Doses of Alprazolam in Healthy Volunteers

2007 ◽  
Vol 55 (3-4) ◽  
pp. 203-212 ◽  
Author(s):  
M.J. Barbanoj ◽  
G. Urbano ◽  
R. Antonijoan ◽  
M.R. Ballester ◽  
M. Valle
1996 ◽  
Vol 54 (2) ◽  
pp. 501-508 ◽  
Author(s):  
Santosh Yajnik ◽  
James P. Zacny ◽  
Christopher J. Young ◽  
J.Lance Lichtor ◽  
Gita Rupani ◽  
...  

Author(s):  
M. C. Perault ◽  
L. Bergougnan ◽  
A. Paillat ◽  
I. Zieleniuk ◽  
P. Rosenzweig ◽  
...  

1999 ◽  
Vol 54 (11) ◽  
pp. 821-827 ◽  
Author(s):  
S. D. Ferrara ◽  
R. Giorgetti ◽  
S. Zancaner ◽  
R. Orlando ◽  
A. Tagliabracci ◽  
...  

Author(s):  
Suganthi S. Ramachandran ◽  
Vijay L. Kumar ◽  
S. N. Dwivedi ◽  
Vishwajeet Singh ◽  
Pooja Gupta

Background: This study aimed to compare the effect of regular coffee and decaffeinated coffee on psychomotor performance in healthy volunteers during post-lunch period.Methods: In this randomized double-blind cross-over study, adult healthy volunteers were given hot coffee (3 g each of regular or decaffeinated coffee) during post-lunch period. Psychomotor functions (critical flicker-fusion frequency (CFF), choice reaction time (CRT) and error count in hand-steadiness test (HST)), blood pressure and heart rate were measured pre-lunch, pre-coffee (1-hour post-lunch) and 1-hour post-coffee consumption. Subjective ratings of sleepiness and mood were also assessed during post-lunch sessions.Results: The mean age of the participants (n=16) was 27.4±2.7 years with a male: female ratio of 7:9. There was no significant deterioration in psychomotor performance post-lunch when compared to pre-lunch on both the days. The mean CFF, CRT, errors committed in HST and cardiovascular parameters did not differ significantly between regular coffee and decaffeinated groups during post-lunch sessions. There was no significant difference in values of cardiovascular parameters as well as subjective ratings of sleep and mood between two groups.Conclusions: In healthy adult individuals’ consumption of both regular coffee and decaffeinated coffee during the post-lunch period did not affect psychomotor performance.


1994 ◽  
Vol 113 (3-4) ◽  
pp. 304-310 ◽  
Author(s):  
John Ingum ◽  
Roald Bjørklund ◽  
Rolf Volden ◽  
Jørg Mørland
Keyword(s):  

1995 ◽  
Vol 9 (2) ◽  
pp. 143-149 ◽  
Author(s):  
D.J. King ◽  
P. Best ◽  
G. Lynch ◽  
M.F. Mannion ◽  
R.C. Montgomery ◽  
...  

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