Endogenous Sex Hormones in Women with Ischemic Stroke

1996 ◽  
Vol 6 (5) ◽  
pp. 288-293 ◽  
Author(s):  
Lise Leth Jeppesen ◽  
Henrik Stig Jørgensen ◽  
Hirofumi Nakayama ◽  
Hans Otto Raaschou ◽  
Tom Skyhøj Olsen ◽  
...  
2020 ◽  
Vol 147 (4) ◽  
pp. 920-930 ◽  
Author(s):  
Wanshui Yang ◽  
Edward L. Giovannucci ◽  
Susan E. Hankinson ◽  
Andrew T. Chan ◽  
Yanan Ma ◽  
...  

2013 ◽  
Vol 36 (3) ◽  
pp. 388-426 ◽  
Author(s):  
Lisa Boss ◽  
Duck-Hee Kang ◽  
Marianne Marcus ◽  
Nancy Bergstrom

2004 ◽  
Vol 89 (3) ◽  
pp. 1240-1245 ◽  
Author(s):  
Katharine H. Mikulec ◽  
Leah Holloway ◽  
Ruth E. Krasnow ◽  
Harold Javitz ◽  
Gary E. Swan ◽  
...  

2010 ◽  
pp. OR17-2-OR17-2
Author(s):  
GA Laughlin ◽  
CL Wassel ◽  
K Cummins ◽  
E Barrett-Connor

2008 ◽  
Vol 7 ◽  
pp. 23-28
Author(s):  
B. M. Doronin ◽  
Ye. A. Vas’kina ◽  
O. A. Denisova

The aim of work is to exposure how disbalance of male sex hormones in the period of the age-specific reorganization affects development of atherosclerosis and vascular disorders by the example of ischemic stroke, establishment of correlation between hormonal dysfunction by the example testosterone and lipid metabolism according to the somatic type in the critical period of ischemic stroke. The pilot analysis of level of sex hormones by the example testosterone, lipids and body mass index confirms that there is correlation between these indices. Rising of body mass index is accompanied by reduction of sex hormone concentration, but for all that levels of cholesterol and atherogenic fraction are increased.


2016 ◽  
Vol 10 (1) ◽  
pp. 48-52
Author(s):  
Shakir F.T. Al-Aaraji

The objective of this cross sectional study was to assess the effect of diabetes mellitus (DM) type 2  in men on endogenous sex hormones: estradiol (E2) and  total testosterone (TT); pituitary gland hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH)  as well as high sensitive C-Reactive protein (hs-CRP) in men. This study comprised a total of (80) subjects out of which (40) were normal and (40) were diabetic males. The results obtained indicated a significant increasing (p≤ 0.05) of serum hs-CRP and E2 in men with DM type 2 comparison to non-diabetics, while a significant reduction (p≤ 0.05) of  serum testosterone in men with DM type 2 comparison to non-diabetics, and non-significant reduction of serum LH, FSH in men with DM type 2 comparison to non-diabetics were observed. The data from this study show the role of endogenous sex hormones and hs-CRP in diabetes risk. Testosterone levels are partly influenced by insulin resistance, which may represent an important avenue for intervention


2020 ◽  
Author(s):  
Jung-Won Choi ◽  
In Woo Ryoo ◽  
Jun Yeong Hong ◽  
Kyung-Yul Lee ◽  
Hyo Suk Nam ◽  
...  

Abstract Background: Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are associated with infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual hormones are considered neuroprotective agents. The purpose of this study was to assess the role of sex hormones and the ratio of estradiol/testosterone (E/T) in patients with acute ischemic stroke (AIS).Methods: Between January 2011 and December 2016, 146 male patients with AIS and 152 age- and sex-matched control subjects were included in this study. Sex hormones, including estradiol, progesterone, and testosterone, were evaluated in the AIS patient and control groups. We analyzed the clinical and physiological levels of sex hormones and hormone ratios in these patients.Results: The E/T ratio was significantly elevated among patients in the stroke group compared to those in the control group (P = 0.001). Categorization of data into tertiles revealed that patients with the highest E/T ratio were more likely to have AIS [odds ratio (OR) 3.084; 95% Confidence interval (CI): 1.616-5.886; P < 0.001) compared with those in the first tertile. The E/T ratio was also an independent unfavorable outcome predictor with an adjusted OR of 1.167 (95% CI: 1.053-1.294; P = 0.003).Conclusions: These findings support the hypothesis that increased estradiol and reduced testosterone levels are associated with AIS in men.


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