scholarly journals Impact of Upward Lymph Node Dissection on Survival Rates in Advanced Lower Rectal Carcinoma

2007 ◽  
Vol 24 (5) ◽  
pp. 375-381 ◽  
Author(s):  
Keisuke Uehara ◽  
Seiichiro Yamamoto ◽  
Shin Fujita ◽  
Takayuki Akasu ◽  
Yoshihiro Moriya
2009 ◽  
Vol 32 (1-2) ◽  
pp. 57-61 ◽  
Author(s):  
Jonas Göhl ◽  
Werner Hohenberger ◽  
Susanne Merkel

1994 ◽  
Vol 81 (2) ◽  
pp. 293-296 ◽  
Author(s):  
L. F. Moreira ◽  
A. Hizuta ◽  
H. Iwagaki ◽  
N. Tanaka ◽  
K. Orita

2015 ◽  
Vol 96 (6) ◽  
pp. 930-935
Author(s):  
A F Gilmetdinov ◽  
V P Potanin

Aim. The analysis of the survival rates depending on the extent of surgery and the influence of ipsilateral bronchopulmonary lymph node dissection on this indicator. Methods. Medical charts of 1324 in- and outpatients who underwent surgeries in the department of thoracic surgery №1 in 2000-2009 were analyzed. Patients were allocated to the groups (944 patients in total) according to clinical form and stage (peripheral cancer - 555 patients, central cancer - 389 patients), histological type (peripheral cancer - 254 patients with adenocarcinoma and 204 patients with squamous cell carcinoma, central cancer - 44 patients with adenocarcinoma and 304 patients with squamous cell carcinoma). 5-year survival rate was calculated in each group depending on the extent of surgery (lobectomy, pneumonectomy), and the impact of ipsilateral bronchopulmonary lymph node dissection that was performed in all cases of pulmonectomy on this indicator was analyzed. Results. After lobectomy, 5-year survival rates were similar in both groups - 57.08 and 55.14% (p=0.8). However, 5-year survival rate in patients after pneumonectomy due to central lung cancer (41.13%) was significantly higher compared to peripheral cancer (26.83%, p=0.02). Survival rates for the certain stages of the disease after pneumonectomy due to central cancer were significantly higher when compared to peripheral cancer. No significant differences in survival rates in different histological types of peripheral cancer and in the central form of lung adenocarcinoma were revealed, in contrast to squamous cell cancer. The survival rates after pulmonectomy in cases of central squamous cancer were only slightly different from those after lobectomy. Gained preliminary data of retrospective analysis reflect the influence of lymph node dissection on survival. Conclusion. The best results after pneumonectomy were obtained in patients with central form of squamous cell carcinoma. However, in the cases of peripheral cancer early stages of the disease prevailed after lobectomy, which obviously increased survival rates. If proven, the proposed method will enhance the survival rates in patients with non-small cell lung cancer.


2018 ◽  
Vol 5 (11) ◽  
pp. 3531
Author(s):  
Süleyman Orman ◽  
Haydar Yalman ◽  
Mehmet Rafet Yiğitbaşı

Background: Cure may only be achieved through surgical resection in gastric cancer. In this paper, we retrospectively analyzed the effects of D1 and D2 dissection and type of the performed operation as well as type of the hospital on survival.Methods: Total of 125 patients, who had been operated for gastric cancer in two separate hospitals between January 2003 and June 2007 were retrospectively studied. The patients who met the criteria of the study were divided into four groups according to the operation type. Difference between the survival rates, median survival of the patients with respect to the type of the operation and hospitals were analyzed.Results: Of the patients, 66 had total gastrectomy + D1 lymph node dissection, 39 had distal subtotal gastrectomy + D1 lymph node dissection, 7 had total gastrectomy + D2 lymph node dissection, and 13 had distal subtotal gastrectomy + D2 lymph node dissection. Analysis of 3-year survival of the patients demonstrated no statistically significant difference between the groups with respect to the survival rates, median survival of the patients and the hospitals (p<0.05).Conclusions: This study indicated that there was no significant difference between survivals with regard to the institution where the operation had been performed, the operation type and the extent of the dissection.


2016 ◽  
Vol 34 (2_suppl) ◽  
pp. 450-450
Author(s):  
Maxine Sun ◽  
Guillermo de Velasco ◽  
Christian P Meyer ◽  
Joaquim Bellmunt ◽  
Paul L. Nguyen ◽  
...  

450 Background: Previous studies are inconclusive on whether urachal vs. non-urachal adenocarcinomas of the urinary bladder have different prognoses. Our objective was to assess survival differences between urachal vs. non-urachal adenocarcinomas in light of evolving treatment strategies over the past years. Methods: The Surveillance, Epidemiology, and End Results (SEER) database was used to identify patients with a diagnosis of adenocarcinoma of the urinary bladder between years 1988 and 2012. The variable of interest was urachal vs. non-urachal adenocarcinomas. Kaplan-Meier curves and log-rank tests were performed to assess the univariable effect of urachal vs. non-urachal adenocarcinomas on survival. Multivariable Cox regression analyses were performed for prediction of cancer-specific mortality (CSM) and overall mortality. Sub-analyses comprised of competing-risks regression models. Results: Overall, 2345 (89%) and 301 (11%) non-urachal and urachal adenocarcinoma patients were identified, respectively. The 5-year CSM-free survival rates for urachal vs. non-urachal adenocarcinomas were 63% vs. 50% (P< 0.001). For the same groups, the 5-year overall survival rates were 50% vs. 32%, respectively (P< 0.001). In multivariable Cox regression analyses, no difference was recorded between urachal vs. non-urachal adenocarcinomas for CSM (hazard ratio [HR]: 0.86, P= 0.2) or any mortality (HR: 0.84, P= 0.07). Important prognosticators of CSM and survival were surgery, lymph node dissection, disease stage and grade. Conclusions: No survival difference was recorded in the current study between urachal vs. non-urachal adenocarcinoma of the bladder. However, surgery and lymph node dissection constitute important factors for both tumor types.


2021 ◽  
Vol 20 (4) ◽  
pp. 84-90
Author(s):  
F. Sh. Akhmetzyanov ◽  
A. H. Kaulgud ◽  
F. F. Akhmetzyanova

The aim of the study was to improve surgical outcomes in patients with proximal gastric cancer without invading the esophagus.Material and methods. Data regarding lymph node metastasis, short-term postoperative complications/lethality, and long-term outcomes were analyzed in 162 patients with proximal gastric cancer without invasion of the esophagus. All patients underwent gastrosplenectomy with expanded d2 lymph node dissection. The age of the patients ranged from 25 to 91 years, and the median age was 60 years. There were 105 (64.8 %) patients aged over 60 years and 45 (27.8 %) over 70 years.Results. Postoperative complications occurred in 14 patients (8.6 %), 8 of them (4.9 %) died. The 1-, 3- and 5 year survival rates were 85.4 %, 61.8 %, and 38.9 %, respectively.Discussion. In patients with gastric cancer without esophageal invasion, perigastric lymph nodes (№ 3b, 4d) located in segments iv and v are often affected by metastases; therefore, we consider it inexpedient to perform proximal resections in these cases.Conclusion. In patients with proximal gastric cancer without esophageal invasion, it is not advisable to perform proximal subtotal gastric resections due to the high frequency of 3b and 4d lymph node metastases. Postoperative complication and mortality rates were 8.6 % and 4.9 %, respectively in patients who underwent gastrosplenectomy with d2 lymph node dissection.


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