Helical Tomotherapy: Image Guidance and Adaptive Dose Guidance

2007 ◽  
pp. 162-178 ◽  
Author(s):  
Wolfgang A. Tomé ◽  
Hazim A. Jaradat ◽  
Ian A. Nelson ◽  
Mark A. Ritter ◽  
Minesh P. Mehta
Keyword(s):  
Image Guidance ◽  
Helical Tomotherapy

Evidence of Limited Motion of the Prostate by Carefully Emptying the Rectum as Assessed by Daily MVCT Image Guidance with Helical Tomotherapy

2008 ◽  
Vol 71 (2) ◽  
pp. 611-617 ◽  
Author(s):  
Claudio Fiorino ◽  
Nadia Di Muzio ◽  
Sara Broggi ◽  
Cesare Cozzarini ◽  
Eleonora Maggiulli ◽  
...  
Keyword(s):  
Image Guidance ◽  
Helical Tomotherapy ◽  
Limited Motion

Accuracy of manual and automated rectal contours using helical tomotherapy image guidance scans during prostate radiotherapy.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 94-94 ◽  
Author(s):  
Jessica Elizabeth Scaife ◽  
Karl Harrison ◽  
Amelia Drew ◽  
Xiaohao Cai ◽  
Juheon Lee ◽  
...  
Keyword(s):  
Ct Scan ◽  
Image Guidance ◽  
Helical Tomotherapy ◽  
Normal Structure ◽  
Conformity Index ◽  
Observer Variability ◽  
Prostate Radiotherapy ◽  
Manual Contour ◽  
Initial Cohort ◽  
Automated Methods

94 Background: Prostate radiotherapy can be delivered using daily image-guided helical tomotherapy. Previous work has shown that contouring the rectum on the kV planning CT scan has a Jaccard conformity index (JCI) of 0.78 for different oncologists (inter-observer variability) and 0.82 for a single oncologist (intra-observer variability) (Lutgendorf-Caucig C et al. Feasibility of CBCT-based target and normal structure delineation in prostate cancer radiotherapy: multi-observer and image multi-modality study. Radiother Oncol. 2011;98(2):154-61.). Using the daily image guidance MV CT scan we have developed automated methods to contour the rectum in order to investigate the dose delivered over a course of treatment. We sought to quantify the accuracy of MV manual and automated contours. Methods: A single oncologist (JES) contoured the rectum on 370 MV scans for 10 participants treated with helical tomotherapy to prostate and pelvic lymph nodes. Accuracy of MV manual contours was tested using a scalar algorithm to enlarge and reduce the contours and intra-observer re-contouring at a 3-month interval. Automated contouring, incorporating the Chan-Vese algorithm, was developed and outputs were compared with manual contours. Results: JES could identify differences in MV manual contour size at the level of ±2.2 mm, equivalent to 1.7 pixels. The median JCI for MV re-contouring was 0.87 with inter-quartile range (IQR) 0.78 to 0.90. When compared with manual contours, automated outputs had a median JCI of 0.79 (IQR 0.74 to 0.79). These results were obtained after 3 iterations, each taking less than 10 seconds. Conclusions: Manual contouring using MV scans was accurate, at a level of approximately 2 mm, and reproducible, with JCI of 0.87. The time taken to contour was approximately 20 minutes per scan. Automated contouring was also reproducible with JCI of 0.79 and, in contrast, took less than a minute per scan. Both manual and automated methods produced results comparable to those for contouring using kV scans. We plan to use auto-contouring to calculate accumulated dose to the rectum in an initial cohort of 100 participants. These doses will be correlated with toxicity as part of the VoxTox Study.

scholarly journals Efficacy and safety of image-guidance radiotherapy by helical tomotherapy in patients with lung cancer

Medicine ◽  
2018 ◽  
Vol 97 (1) ◽  
pp. e9243 ◽  
Author(s):  
Xiang-ru Chen ◽  
Jia-nan Dong ◽  
Fan Zhang ◽  
Tian-ling Yao
Keyword(s):  
Lung Cancer ◽  
Image Guidance ◽  
Helical Tomotherapy ◽  
Efficacy And Safety

scholarly journals EP-1260: Helical Tomotherapy with Daily Image Guidance for Rectal Cancer patients

2017 ◽  
Vol 123 ◽  
pp. S678
Author(s):  
B. De Bari ◽  
A. Franzetti-Pellanda ◽  
A. Saidi ◽  
M. Biggiogero ◽  
D. Hahnloser ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Cancer Patients ◽  
Image Guidance ◽  
Helical Tomotherapy
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