scholarly journals Clinical Significance of Lobar Atrophy in Frontotemporal Dementia: Application of an MRI Visual Rating Scale

2007 ◽  
Vol 23 (5) ◽  
pp. 334-342 ◽  
Author(s):  
Christopher M. Kipps ◽  
R. Rhys Davies ◽  
Joanna Mitchell ◽  
Jillian J. Kril ◽  
Glenda M. Halliday ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Clinical Significance ◽  
Rating Scale ◽  
Visual Rating ◽  
Visual Rating Scale

scholarly journals Fronto-striatal atrophy correlates of neuropsychiatric dysfunction in frontotemporal dementia (FTD) and Alzheimer's disease (AD)

2013 ◽  
Vol 7 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Dong Seok Yi ◽  
Maxime Bertoux ◽  
Eneida Mioshi ◽  
John R. Hodges ◽  
Michael Hornberger
Keyword(s):  
Frontotemporal Dementia ◽  
Rating Scale ◽  
Brain Regions ◽  
Abnormal Behaviour ◽  
Behavioural Symptoms ◽  
Visual Rating ◽  
Prefrontal Cortical ◽  
Mri Scans ◽  
Visual Rating Scale ◽  
Cortical Regions

ABSTRACT Behavioural disturbances in frontotemporal dementia (FTD) are thought to reflect mainly atrophy of cortical regions. Recent studies suggest that subcortical brain regions, in particular the striatum, are also significantly affected and this pathology might play a role in the generation of behavioural symptoms. Objective: To investigate prefrontal cortical and striatal atrophy contributions to behavioural symptoms in FTD. Methods: One hundred and eighty-two participants (87 FTD patients, 39 AD patients and 56 controls) were included. Behavioural profiles were established using the Cambridge Behavioural Inventory Revised (CBI-R) and Frontal System Behaviour Scale (FrSBe). Atrophy in prefrontal (VMPFC, DLPFC) and striatal (caudate, putamen) regions was established via a 5-point visual rating scale of the MRI scans. Behavioural scores were correlated with atrophy rating scores. Results: Behavioural and atrophy ratings demonstrated that patients were significantly impaired compared to controls, with bvFTD being most severely affected. Behavioural-anatomical correlations revealed that VMPFC atrophy was closely related to abnormal behaviour and motivation disturbances. Stereotypical behaviours were associated with both VMPFC and striatal atrophy. By contrast, disturbance of eating was found to be related to striatal atrophy only. Conclusion: Frontal and striatal atrophy contributed to the behavioural disturbances seen in FTD, with some behaviours related to frontal, striatal or combined fronto-striatal pathology. Consideration of striatal contributions to the generation of behavioural disturbances should be taken into account when assessing patients with potential FTD.

scholarly journals Aggressiveness between genetic groups I and II of isolates of Cercospora zeae-maydis

2006 ◽  
Vol 63 (6) ◽  
pp. 547-551 ◽  
Author(s):  
Sandra Marisa Mathioni ◽  
Carvalho ◽  
Kátia Regiane Brunelli ◽  
André Beló ◽  
Luis Eduardo Aranha Camargo
Keyword(s):  
Rating Scale ◽  
Zea Mays L ◽  
Gray Leaf Spot ◽  
Leaf Spot Disease ◽  
5.8S Rdna ◽  
Visual Rating ◽  
Genetic Groups ◽  
Group I ◽  
Cercospora Zeae Maydis ◽  
Visual Rating Scale

For many years, the gray leaf spot disease (GLS) caused by the fungus Cercospora zeae-maydis Tehon & Daniels, was not considered an important pathogen of maize (Zea mays, L.) in Brazil. However, the recent adoption of agronomical practices such as no-tillage and cultivation under central pivot irrigation systems increased the incidence and severity to the extent that GLS is now one of the most important diseases of maize. Isolates of C. zeae-maydis can be distinguished by two genetic groups (I and II) based on AFLP markers and on polymorphisms of the ITS and 5.8S rDNA regions. Until now, however, the biological implications of this distinction remain unclear. This study investigated whether isolates from the two genetic groups differ in aggressiveness towards maize. For this, symptoms of a susceptible hybrid were evaluated under greenhouse conditions with 9 and 11 isolates of C. zeae-maydis from groups I and II, respectively. Plants in the V3 growth stage were inoculated by placing sorghum seeds colonized with the pathogen in the leaf whorl and symptoms were evaluated with a visual rating scale 30 days later. On average, isolates of genetic group II were more aggressive than those of group I, with mean disease scores of 3.1 and 2.3, respectively. Differences were also observed between experiments, which suggested that group I and II might also differ in their fitness under different environments. This is the first report on differences in aggressiveness between the two genetic groups of C. zeae-maydis.

scholarly journals A New Visual Rating Scale to Assess Strategic White Matter Hyperintensities Within Cholinergic Pathways in Dementia

Stroke ◽  
2005 ◽  
Vol 36 (10) ◽  
pp. 2126-2131 ◽  
Author(s):  
Christian Bocti ◽  
Richard H. Swartz ◽  
Fu-Qiang Gao ◽  
Demetrios J. Sahlas ◽  
Pearl Behl ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Hyperintensities ◽  
Rating Scale ◽  
Visual Rating ◽  
Cholinergic Pathways ◽  
Visual Rating Scale

Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition

2015 ◽  
Vol 26 (8) ◽  
pp. 2597-2610 ◽  
Author(s):  
Daniel Ferreira ◽  
◽  
Lena Cavallin ◽  
Tobias Granberg ◽  
Olof Lindberg ◽  
...  
Keyword(s):  
Rating Scale ◽  
Clinical Status ◽  
Csf Biomarkers ◽  
Visual Rating ◽  
Visual Rating Scale ◽  
Quantitative Validation

scholarly journals A ‘Comprehensive Visual Rating Scale’ for predicting progression to dementia in patients with mild cognitive impairment

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0201852 ◽  
Author(s):  
Jae-Won Jang ◽  
Jeong Hoon Park ◽  
Seongheon Kim ◽  
Young Ho Park ◽  
Jung-Min Pyun ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rating Scale ◽  
Visual Rating ◽  
Visual Rating Scale

Combining Visual Rating Scales for Medial Temporal Lobe Atrophy and Posterior Atrophy to Identify Amnestic Mild Cognitive Impairment from Cognitively Normal Older Adults: Evidence Based on Two Cohorts

2020 ◽  
Vol 77 (1) ◽  
pp. 323-337
Author(s):  
Can Sheng ◽  
Yu Sun ◽  
Min Wang ◽  
Xiaoni Wang ◽  
Yi Liu ◽  
...  
Keyword(s):  
Medial Temporal Lobe ◽  
Rating Scales ◽  
Rating Scale ◽  
Discriminative Power ◽  
Medial Temporal Lobe Atrophy ◽  
Cognitively Normal ◽  
Visual Rating ◽  
Visual Rating Scale ◽  
Visual Assessments ◽  
Lobe Atrophy

Background: Visual rating scales for medial temporal lobe atrophy (MTA) and posterior atrophy (PA) have been reported to be useful for Alzheimer’s disease diagnosis in routine clinical practice. Objective: To investigate the efficacy of combined MTA and PA visual rating scales to discriminate amnestic mild cognitive impairment (aMCI) patients from healthy controls. Methods: This study included T1-weighted MRI images from two different cohorts. In the first cohort, we recruited 73 patients with aMCI and 48 group-matched cognitively normal controls for training and validation. Visual assessments of MTA and PA were carried out for each participant. Global gray matter volume and density were estimated using voxel-based morphometry analysis as the objective reference. We investigated the discriminative power of a single visual rating scale and the combination of the MTA and PA rating scales for identifying aMCI. The second cohort, consisting of 33 aMCI patients and 45 controls, was used to verify the reliability of the visual assessments. Results: Compared with the single visual rating scale, the combination of the MTA and PA exhibited the best discriminative power, with an AUC of 0.818±0.041, which was similar to the diagnostic accuracy of the gray matter volumetric measures. The discriminative power of the combined MTA and PA was verified in the second cohort (AUC 0.824±0.058). Conclusion: The combined MTA and PA rating scales demonstrated practical diagnostic value for distinguishing aMCI patients from controls, suggesting its potential to serve as a convenient and reproducible method to assess the degree of atrophy in clinical settings.

A Visual Rating Scale for Prints of Finger-Sweat

1963 ◽  
Vol 76 (1) ◽  
pp. 140 ◽  
Author(s):  
John Kenyon ◽  
Herbert F. Muller
Keyword(s):  
Rating Scale ◽  
Visual Rating ◽  
Visual Rating Scale
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