Quality Assessment of Magnetic Resonance Stereotactic Localization for Gamma Knife Radiosurgery

1995 ◽  
Vol 64 (1) ◽  
pp. 228-232 ◽  
Author(s):  
E. Piovan ◽  
P.G. Zampieri ◽  
F. Alessandrini ◽  
M.A. Gerosa ◽  
A. Nicolato ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Quality Assessment ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Stereotactic Localization

scholarly journals Clinical impact of magnetic resonance imaging distortions on gamma knife radiosurgery

2021 ◽  
Author(s):  
Sinead Jacobson ◽  
Catherine Jones ◽  
Ryan Lusk ◽  
Mike Jenkins ◽  
Crispen Chamunyonga ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Clinical Impact ◽  
Resonance Imaging

scholarly journals USE OF PROTON MAGNETIC RESONANCE SPECTROSCOPIC IMAGING DATA IN PLANNING FOCAL RADIATION THERAPIES FOR BRAIN TUMORS

2011 ◽  
Vol 21 (2) ◽  
pp. 69 ◽  
Author(s):  
Edward E Graves ◽  
Andrea Pirzkall ◽  
Tracy R Mcknight ◽  
Daniel B Vigneron ◽  
David A Larson ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Spectroscopic Imaging ◽  
Target Volume ◽  
Magnetic Resonance Spectroscopic Imaging ◽  
Malignant Neoplasms ◽  
Resonance Spectroscopy ◽  
Normal Brain ◽  
Imaging Data

Advances in radiation therapy for malignant neoplasms have produced techniques such as Gamma Knife radiosurgery, capable of delivering an ablative dose to a specific, irregular volume of tissue. However, efficient use of these techniques requires the identification of a target volume that will produce the best therapeutic response while sparing surrounding normal brain tissue. Accomplishing this task using conventional computed tomography (CT) and contrast-enhanced magnetic resonance imaging (MRI) techniques has proven difficult because of the difficulties in identifying the effective tumor margin. Magnetic resonance spectroscopic imaging (MRSI) has been shown to offer a clinically-feasible metabolic assessment of the presence and extent of neoplasm that can complement conventional anatomic imaging. This paper reviews current Gamma Knife protocols and MRSI acquisition, reconstruction, and interpretation techniques, and discusses the motivation for including magnetic resonance spectroscopy findings while planning focal radiation therapies. A treatment selection and planning strategy incorporating MRSI is then proposed, which can be used in the future to assess the efficacy of spectroscopy-based therapy planning.

Stagnant Venous Outflow Predicts Brain Arteriovenous Malformation Obliteration After Gamma Knife Radiosurgery Without Prior Intervention

Neurosurgery ◽  
2019 ◽  
Vol 87 (2) ◽  
pp. 338-347 ◽  
Author(s):  
Yong-Sin Hu ◽  
Cheng-Chia Lee ◽  
Hsiu-Mei Wu ◽  
Huai-Che Yang ◽  
Te-Ming Lin ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Digital Subtraction Angiography ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Magnetic Resonance Images ◽  
Venous Stasis ◽  
Digital Subtraction ◽  
Venous Outflow ◽  
Therapeutic Decisions ◽  
The Impact

Abstract BACKGROUND Gamma Knife radiosurgery (GKRS) obliterates 65% to 82% of brain arteriovenous malformations (BAVMs). OBJECTIVE To explore the impact of hemodynamics on GKRS outcomes. METHODS We retrospectively (2011-2017) included 98 patients with BAVMs who had received GKRS alone. Two evaluators, blinded to the outcomes, analyzed the pre-GKRS angiography and magnetic resonance images to obtain the morphological characteristics and quantitative digital subtraction angiography (QDSA) parameters. The venous stasis index was defined as the inflow gradient divided by the absolute value of the outflow gradient. Patients’ follow-up magnetic resonance or digital subtraction angiography images were evaluated for the presence of complete obliteration (CO). Cox regression and Kaplan–Meier analyses were conducted to determine the correlations between the parameters and outcomes. RESULTS Among the 98 patients, 63 (63.4%) achieved CO after GKRS at a median latency period of 31 mo. In multivariable analyses with adjustments for age and sex, increased BAVM volume (hazard ratio (HR) 0.949, P = .022) was an independent characteristic predictor, and venous stenosis (HR 2.595, P = .009), venous rerouting (HR 0.375, P = .022), and larger stasis index (HR 1.227, P = .025) were independent angiographic predictors of CO. BAVMs with a stasis index of >1.71 had a higher 36-mo probability of CO than those with a stasis index of ≤1.71 (61.1% vs 26.7%, P < .001). CONCLUSION BAVMs with a larger stasis index, indicating more stagnant venous outflow, may predict obliteration after GKRS. QDSA analysis may help in predicting BAVM treatment outcomes and making therapeutic decisions.

Can magnetic resonance imaging alone accurately define the arteriovenous nidus for gamma knife radiosurgery?

2002 ◽  
Vol 97 ◽  
pp. 464-470 ◽  
Author(s):  
E. J. St. George ◽  
P. Butler ◽  
P. N. Plowman
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Resonance Imaging ◽  
Systemic Complications ◽  
Content Type ◽  
Weighted Sequences ◽  
Fine Print

Object. Current radiosurgical treatment of arteriovenous malformations (AVMs) relies on planning protocols that integrate data from both magnetic resonance (MR) imaging and stereotactic angiography studies. Angiography, however, is invasive and associated with a small but well-defined risk of neurological and systemic complications. Magnetic resonance imaging, on the other hand, is noninvasive with multiplanar capability, demonstrates good anatomical detail, and has been shown to be superior to angiography in the delineation of selected AVMs. Methods. In this study, MR imaging—related accuracy of defining the AVM nidus in gamma knife radiosurgery is investigated using only T1- and T2-weighted sequences. Conclusions. Little interobserver variability was observed and AVM nidi, as demonstrated on T1- and T2-weighted MR images, were well correlated in terms of size. The displacement of the new target, however, from the original nidus, was not predictable and occasionally was significant, thus precluding safe radiosurgical planning.

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