Severe Immediate Allergic Reactions to Grapes: Part of a Lipid Transfer Protein-Associated Clinical Syndrome

2007 ◽  
Vol 143 (2) ◽  
pp. 92-102 ◽  
Author(s):  
Emilia Vassilopoulou ◽  
Laurian Zuidmeer ◽  
Jaap Akkerdaas ◽  
Ioannis Tassios ◽  
Neil R. Rigby ◽  
...  
Keyword(s):  
Lipid Transfer Protein ◽  
Clinical Syndrome ◽  
Allergic Reactions ◽  
Lipid Transfer ◽  
Transfer Protein

Severe Reactions to Grape, As Part of a Lipid Transfer Protein-Associated Clinical Syndrome

2006 ◽  
Vol 117 (2) ◽  
pp. S301 ◽  
Author(s):  
E. Vassilopoulou ◽  
J. Akkerdaas ◽  
I. Tassios ◽  
N. Rigby ◽  
L. Zuidmeer ◽  
...  
Keyword(s):  
Lipid Transfer Protein ◽  
Clinical Syndrome ◽  
Lipid Transfer ◽  
Transfer Protein

scholarly journals Expression Activity of Allergen Coding Genes in Grape Varieties Used for Tokaj Wine Production

2020 ◽  
Vol 23 (1) ◽  
pp. 31-32
Author(s):  
Jana Žiarovská ◽  
Lucia Zamiešková ◽  
Miroslava Kačániová
Keyword(s):  
Vitis Vinifera ◽  
Lipid Transfer Protein ◽  
Slovak Republic ◽  
Allergic Reactions ◽  
Lipid Transfer ◽  
Wine Production ◽  
Transfer Protein ◽  
Expression Activity ◽  
Wine Region ◽  
Grape Varieties

AbstractVitis vinifera L. is adapted to a very variable range of climates but it mostly grows in the temperate regions of continental Europe. In the Slovak Republic, the Tokaj wine region is one of the territories, where wine production is concentrated. Grape is a popular fruit and when processed, it is used as musts, juices or wine. Some people may suffer from allergic reactions to grapes. Up to now, endochitinases, lipid-transfer protein, and thaumatin were identified as grape allergens. In this study, expression of chitinase and thaumatin allergen was analysed in the grapes of Tokaj region varieties – Hachat Lovelin, Tokay and Muskat Blanc. Expression changes were calculated by the delta delta Ct method. Expression differences of chitinase were found to be similar in these varieties. Thaumatin was found to be variable in its transcription.

The maize major allergen, which is responsible for food-induced allergic reactions, is a lipid transfer protein

2000 ◽  
Vol 106 (4) ◽  
pp. 744-751 ◽  
Author(s):  
Elide A. Pastorello ◽  
Laura Farioli ◽  
Valerio Pravettoni ◽  
Marco Ispano ◽  
Elisabetta Scibola ◽  
...  
Keyword(s):  
Lipid Transfer Protein ◽  
Major Allergen ◽  
Allergic Reactions ◽  
Lipid Transfer ◽  
Transfer Protein

scholarly journals LTP Allergy Follow-Up Study: Development of Allergy to New Plant Foods 10 Years Later

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2165
Author(s):  
Diana Betancor ◽  
Alicia Gomez-Lopez ◽  
Carlos Villalobos-Vilda ◽  
Emilio Nuñez-Borque ◽  
Sergio Fernández-Bravo ◽  
...  
Keyword(s):  
Food Allergy ◽  
Lipid Transfer Protein ◽  
Specific Ige ◽  
Cross Reactivity ◽  
Allergic Reactions ◽  
Plant Food ◽  
Lipid Transfer ◽  
Plant Foods ◽  
Transfer Protein

Introduction: Allergy to nonspecific lipid transfer protein (nsLTP) is the main cause of plant-food allergy in Spain. nsLTPs are widely distributed in the plant kingdom and have high cross-reactivity but extremely variable clinical expression. Little is known about the natural evolution of this allergy, which complicates management. The objective of this study was to assess the development of allergy to new plant foods in nsLTP-sensitized patients 10 years after diagnosis. Methods: One hundred fifty-one patients showing specific IgE to nsLTP determined by ISAC (Thermofisher) were included. After clinical workup (i.e., anamnesis, skin test, and challenge when needed), these patients were divided into two groups: 113 patients allergic to one or more plant food (74.5%) and 38 patients not allergic to any plant food (25.1%). Ten years later, a telephone interview was conducted to check whether patients had developed additional allergic reactions to plant foods. Results: Ten years after diagnosis, 35 of the 113 (31%) plant-food-allergic patients sensitized to nsLTP reported reactions to new, previously tolerated plant foods, mainly Rosaceae/Prunoideae fruits and nuts followed by vegetables, Rosacea/Pomoideae fruits, legumes, and cereals. Five out of 38 (13.2%) patients previously sensitized to nsLTP but without allergy to any plant food had experienced allergic reactions to some plant food: two to Rosaceae/Prunoideae fruits, two to Rosaceae/Prunoideae fruit and nuts, and one to legumes. Conclusion: Patients sensitized to nsLTP developed allergic reactions to other plant foods, mainly Rosaceae-Prunoideae fruits and nuts. This was more frequent among plant-food-allergic patients than among those who had never had plant-food allergy.

scholarly journals The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization

2021 ◽  
pp. 158928
Author(s):  
Zulema Gonzalez-Klein ◽  
Bruno Cuevas-Zuviria ◽  
Andrea Wangorsch ◽  
Guadalupe Hernandez-Ramirez ◽  
Diego Pazos-Castro ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Lipid Transfer Protein ◽  
Lipid Transfer ◽  
Transfer Protein
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