Benefits and Limitations in Vitreoretinal Surgery for Proliferative Diabetic Retinopathy and Macular Edema

Author(s):  
Antonia M. Joussen ◽  
Sandra Joeres
Author(s):  
K.I. Konovalova ◽  
◽  
M.M. Shishkin ◽  

Purpose. The aim is to conduct a comparative analysis of status of macular area of retina of patients with advanced proliferative diabetic retinopathy and complicated incipient cataract according to phacoemulsification surgery time frames: after vitreoretinal surgery only or after vitreoretinal surgery as an integral component. Material and methods: 26 cases of surgery treatment of patients with PDR and complicated primary cataract were analyzed. This patients were divided into two groups depending on the treatment tactics. Retinal thickness in the fovea was measured by optical coherence tomography before surgery and 1 and 3 months after phacoemulsification cataract. Results. Visual functions improved in 85.8% of cases in group 1, and in 66.7% in group 2. Conclusion. Outcomes of the preliminary studies suggest that the frequency of macular edema development after phacoemulsification surgery and IOL implantation with vitreoretinal surgery is recorded more often than when performing with phacoemulsification surgery and silicone oil removal simultaneously by the second stage. Key words: diabetic retinopathy, cataract, vitreoretinal surgery, macular edema.


2021 ◽  
Vol 7 (2) ◽  
pp. 180-183
Author(s):  
Shiv Sagar N ◽  
BN Kalpana ◽  
Shilpa YD

To study the association of cystoid macular edema (CME) and Travoprost eye drops in a patient with diabetic retinopathy (DR).The study was carried out on a 65yr old patient on a regular follow up from 2009-2018.A 65yr old patient of a DR of both eyes who had received 3 sittings of pan retinal photocoagulation (PRP) laser in both eyes and grid laser to his right eye. He was on regular follow up since 2009 with a stable proliferative diabetic retinopathy (PDR). Patient was also on topical antiglaucoma medication and had prophylactic YAG-PI done both eyes. He was on regular follow up since 2009 with a stable proliferative diabetic retinopathy (PDR). Right eye showed macular edema (ME) in 2014 and underwent OCT and FFA. Patient refused for intravitreal injection and preferred laser treatment, so patient underwent micropulse laser treatment in 2014. His edema persisted even after micropulse treatment. His systemic control was good and patient continued to use Travoprost eye drops. So in 2017 suspected CME secondary to topical prostaglandin (PG) analogue as he had strict glycemic control and was no fluctuation in ME. Hence topical PG analogue was withdrawn and stopped. On subsequent follow up after 2 months CME had completely disappeared and the foveal contour returned to normal on OCT. LE was status quo. Patient was followed up for more than 1 year and continuously followed up, 15 days back in June 2018 had no evidence of CME and vision was 6/9 in both eyes.: Differentiation of DME and CME secondary to PG analogue should be made at the earliest.


Diabetic macular edema (DME) is the leading cause of blindness in patients with diabetic retinopathy worldwide. Therapeutic alternatives now include focal/grid laser photocoagulation, vitreoretinal surgery, and intraocular injection of anti-angiogenic and steroid molecules. In patients with recalcitrant DME, especially in those cases when anti-vascular endothelial growth factor (VEGF) agents are contraindicated or a treatment regimen with fewer intravitreal injections is required, intravitreal administration of steroids represents a fundamental alternative. Three intravitreal corticosteroid options for DME treatment are currently available including the dexamethasone delivery system, the fluocinolone acetonide insert, and off-label intravitreal triamcinolone acetonide. All of these drugs are associated with the risk of cataract progression and intraocular pressure elevation. In patients unresponsive to anti-VEGF therapy, pseudophakic, at low risk for glaucoma, or who have significant cardiovascular risk, treatment with long-lasting intraocular steroids is suggested.


2019 ◽  
Vol 135 (6) ◽  
pp. 67
Author(s):  
E. N. Khomyakova ◽  
A. A. Ryabtseva ◽  
S. G. Sergushev ◽  
E. E. Grishina

Retina ◽  
2009 ◽  
Vol 29 (9) ◽  
pp. 1282-1288 ◽  
Author(s):  
DAVID GAUCHER ◽  
PINA FORTUNATO ◽  
AMÉLIE LECLEIRE-COLLET ◽  
TRISTAN BOURCIER ◽  
CLAUDE SPEEG-SCHATZ ◽  
...  

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