Thyroid-Associated Ophthalmopathy in Juvenile Graves’Disease: Clinical, Endocrine and Therapeutic Aspects

2006 ◽  
pp. 192-209
Author(s):  
Gerasimos E. Krassas ◽  
Apostolos Gogakos
Keyword(s):  
Thyroid Associated Ophthalmopathy

Corticosteroids, somatostatin analogous or orbital radiotherapy for thyroid-associated ophthalmopathy

2010 ◽  
Author(s):  
Wei Tang ◽  
Huazong Zeng ◽  
Yongquan Shi ◽  
Zhimin Liu ◽  
Jinwei Cheng ◽  
...  
Keyword(s):  
Orbital Radiotherapy ◽  
Thyroid Associated Ophthalmopathy

scholarly journals Choroidal vascularity index in thyroid-associated ophthalmopathy: a cross-sectional study

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Pasquale Loiudice ◽  
Marco Pellegrini ◽  
Michele Marinò ◽  
Barbara Mazzi ◽  
Ilaria Ionni ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Activity Score ◽  
Enhanced Depth Imaging ◽  
Clinical Activity ◽  
Healthy Controls ◽  
Cross Sectional ◽  
Clinical Activity Score ◽  
Significant Difference ◽  
Thyroid Associated Ophthalmopathy ◽  
Imagej Software

Abstract Background Hemodynamic changes have been observed in patients with Graves’ disease. The aim of our study was to evaluate choroidal vascular change using the choroidal vascularity index (CVI) in patients with thyroid-associated ophthalmopathy (TAO). Methods In this cross-sectional observational study, 40 patients affected by TAO were recruited. Forty healthy individuals, matched for age and sex, served as controls. Foveal enhanced-depth imaging optical coherence tomography scans were obtained from all participants. Images were binarized using the ImageJ software and luminal area (LA) and total choroidal area (TCA) were measured. CVI was calculated as the proportion of LA to TCA. The relation between CVI or subfoveal choroidal thickness (SFCT) and clinical activity score, exophthalmometric value, diplopia status, gender, and age was evaluated. Results CVI was significantly higher in patients with TAO (P = 0.004). No significant difference was observed in SFCT (P = 0.200) and TCA (P = 0.153) comparing TAO patients and healthy controls. LA was significantly higher in TAO group (P = 0.045). On multiple regression analysis, CVI was associated with TCA (P = 0.043). No association was found between SFCT or CVI and TCA, clinical activity score, exophthalmometric value, Inami value, diplopia status, gender or age (P > 0.05). Conclusions This is the first study that has demonstrated an increase in CVI in eyes with TAO compared with healthy controls and has assessed its association with clinical features.

Elevated IL-38 inhibits IL-23R expression and IL-17A production in thyroid-associated ophthalmopathy

2021 ◽  
Vol 91 ◽  
pp. 107300
Author(s):  
Yuan Pan ◽  
Minzhen Wang ◽  
Xiaoqing Chen ◽  
Yuxi Chen ◽  
Siming Ai ◽  
...  
Keyword(s):  
Thyroid Associated Ophthalmopathy

Aberrant brain voxel‐wise resting state fMRI in patients with thyroid‐associated ophthalmopathy

2021 ◽  
Author(s):  
Wen Chen ◽  
Qian Wu ◽  
Lu Chen ◽  
Jiang Zhou ◽  
Huan‐Huan Chen ◽  
...  
Keyword(s):  
Resting State ◽  
Resting State Fmri ◽  
Thyroid Associated Ophthalmopathy
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