Why Isn’t the Causal Relationship between Linoleic Acid and Mortalities from Coronary Heart Disease and Stroke Revealed by Clinical Studies?

Author(s):  
H. Okuyama ◽  
Y. Ichikawa ◽  
Y. Sun ◽  
T. Hamazaki ◽  
W.E.M. Lands
2015 ◽  
Vol 12 (4) ◽  
pp. 69-74
Author(s):  
O D Ostroumova ◽  
V M Fomina ◽  
E A Smolyarchuk

In the article discusses questions of application of b-blockers (b-AB) for the treatment of arterial hypertension, coronary heart disease, chronic heart failure. The data from modern Russian and European recommendations about the place of b-AB in the treatment of cardiovascular diseases. Analyzed in detail the selection of b-AB inside the class from the standpoint of pharmacokinetics, selectivity, study in clinical studies. Data about efficiency and safety of application of metoprolol succinate for the treatment of arterial hypertension, coronary heart disease, chronic heart failure.


2019 ◽  
Vol 1 (9) ◽  
pp. 26-32
Author(s):  
T. V. Pinchuk ◽  
N. V. Orlova

The article provides information on various groups of nitropreparations, their pathogenetic effects, the possibility of their application in various clinical situations. The problems arising from the appointment of nitrates and their solutions are considered. The role of nitro drugs in the treatment of angina pectoris is highlighted. Advantages of modern forms of drugs, including Effox® long, are given. The results of clinical studies of the drug.


2000 ◽  
Vol 86 (5) ◽  
pp. 428-430 ◽  
Author(s):  
Claude Bachmeyer ◽  
Hervé Joly ◽  
Roland Jorest

A 36-year-old man with testicular cancer had an acute myocardial infarction during the first course of chemotherapy with bleomycin, etoposide and cisplatin. Since the patient had no significant risk factors for coronary heart disease, the infarction was likely to be attributable to the chemotherapy regimen. The physiopathological mechanisms of this causal relationship are discussed here.


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