Ultrasound Assessment prior to Laser Photocoagulation for Twin-Twin Transfusion Syndrome for Predicting Intrauterine Fetal Demise after Surgery in Japanese Patients

2006 ◽  
Vol 22 (2) ◽  
pp. 149-154 ◽  
Author(s):  
Keisuke Ishii ◽  
Satoshi Hayashi ◽  
Masahiko Nakata ◽  
Takeshi Murakoshi ◽  
Haruhiko Sago ◽  
...  
2020 ◽  
Author(s):  
Ya-Lan Lin ◽  
Yi-Li Hung ◽  
Chung-Min Shen ◽  
Wu-Shiun Hsieh

Abstract Twin-twin transfusion syndrome (TTTS) is due to unbalanced inter-twin blood flow. We aimed to evaluate neonatal outcomes among surviving co-twins of TTTS without fetal laser photocoagulation after single-twin intrauterine fetal demise (sIUFD). All patients admitted between January 2014 and December 2017 to the neonatal intensive care unit of a medical center were recruited. Moreover, a comprehensive literature review of PubMed from 1993 to 2020 was performed. Medical records of 124 patients were retrieved, including 119 from published literature and five from our institution. Seventy-three (58.8%) patients were born prematurely. In addition, twenty-four (19.3 %) patients presented with anemia at birth, and seventeen (13.7%), four (3.2%), and four (3.2%) neonates had intracranial lesions, acute kidney injury, and gastrointestinal (GI) tract dysmotility, respectively. The overall survival rate was 69.4 %. Among our cases, we found that the hemoglobin level at birth was positively correlated with the duration between co-twin intrauterine fetal demise and the delivery time of the surviving co-twins (rs=0.9, p=0.037). Conclusions: High morbidity and mortality rates were observed among co-twins of TTTS after sIUFD without laser photocoagulation. The shorter duration between diagnosis of sIUFD and surviving twin delivery resulted in more severe anemia.


2021 ◽  
pp. 109352662199902
Author(s):  
Stephanie Shea ◽  
Alberto Paniz-Mondolfi ◽  
Emilia Sordillo ◽  
Michael Nowak ◽  
Fumiko Dekio

Bacillus cereus is a gram-positive, rod-shaped bacterium that is commonly implicated in foodborne illness but has also become increasingly recognized as a source of serious non-gastrointestinal infections, including sepsis, meningitis, and pneumonia. Non-gastrointestinal B. cereus infections have been identified in children, especially in neonates; however, there are no previously described cases of fetal demise associated with B. cereus placental infection. We present a case of acute chorioamnionitis-related intrauterine fetal demise of twin A at 17 weeks gestation, noted two days after selective termination of twin B. Histological examination revealed numerous gram-positive bacilli in placental tissue, as well as fetal vasculature, in the setting of severe acute necrotizing chorioamnionitis and subchorionitis, intervillous abscesses, acute villitis, and peripheral acute funisitis. Cultures of maternal blood and placental tissue both yielded growth of B. cereus. This case underscores the importance of B. cereus as a human pathogen, and specifically demonstrates its potential as an agent of severe intraamniotic and placental infection with poor outcomes for the fetus.


1993 ◽  
Vol 13 (4) ◽  
pp. 269-275
Author(s):  
Kimiko Tamagawa ◽  
Ryoko Ishibashi ◽  
Yoshihiko Mizuno ◽  
Kazuhiko Komiya ◽  
Masaya Oda ◽  
...  

2006 ◽  
Vol 130 (6) ◽  
pp. e90-e92
Author(s):  
Jane Ellaine Tongson-Ignacio ◽  
Zahida Parveen ◽  
Karen Thompson ◽  
John M. Hardman

2018 ◽  
Vol 8 (4) ◽  
pp. 865-873
Author(s):  
Corrie B. Miller ◽  
Tricia Wright

Introduction: Intrauterine fetal demise affects between 0.4-0.8% of pregnancies worldwide. This significant adverse pregnancy outcome continues to be poorly understood. In utero exposure to substances increases the risk of stillbirth to varying degrees according to the type of substance and degree of exposure. The aim of this qualitative narrative review is to investigate common biologic relationships between stillbirth and maternal substance use. Methods: A PubMed literature search was conducted to query the most commonly used substances and biologic mechanisms of stillbirth. Search terms included “stillbirth,” “intrauterine fetal demise,” “placenta,” “cocaine,” “tobacco,” “alcohol,” “methamphetamines,” “opioids/ opiates,” and “cannabis.” Results: There are very few studies identifying a direct link between substance use and stillbirth. Several studies demonstrate associations with placental lesions of insufficiency including poor invasion, vasoconstriction, and sequestration of toxic substances that inhibit nutrient transport. Restricted fetal growth is the most common finding in pregnancies complicated by all types of substance use. Discussion: More research is needed to understand the biologic mechanisms of stillbirth. Such knowledge will be foundational to understanding how to prevent and treat the adverse effects of substances during pregnancy.


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